Matching questions
1-184 of 184
Click a definition to match it with a term
Anaphylaxis
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Most life-threatening reaction; occurs in very small number of highly
allergic individuals
Type IV Hypersensitivity
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Delayed hypersensitivity
- Tissue damage resulting from a delayed cellular reaction to an antigen
-No primary antibody involvement
Principal mediators (Lymphocytes & Macrophages)
Hemolytic Disease of the Newborn
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Fetal RBCs cross placenta, stimulate
production of maternal antibodies against
Rh+ antigen on fetal RBC not inherited
from mother ** (mother: Rh- blood type)
Maternal antibodies cross into the fetal
circulation causing destruction of fetal cells
-ABO incompatibility most common
-Rh incompatibility more clinically relevant **
Hairy Cell Leukemia Pathogenesis and Clinical Manifestations
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Hairy cells in peripheral blood
Reduced numbers in granulocytes, platelets, red blood cells
Splenomegaly (90%)
Final stage Hemostasis
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clot retraction
Hairy Cell Leukemia
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-Rare, chronic type of leukemia
-2% of adult leukemia but highly treatable
-Median age of presentation: 55 years; 5:1 predominance of males
-B-cell phenotype
-Peculiar cells with hairlike projections on their surface
Tissue Deposition: Intermediate sized complexes
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-Do not fit complement /bind w/ RBCs well
-Not removed by mononuclear phagocyte system well
Transient hypogammaglobulinemia
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, B-cell disorder.
Self-limiting condition.
Infant slow to acquire normal immunoglobulin levels.
Hematopoiesis
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stem cells---reticulocytes(erythroblasts)---mature
red blood cells(erythrocytes)
-Erythropoietin/EPO: Made in kidney (adult)** Fetus and newborn: Liver
and kidney
Renal disease causes anemia
-Functions in bone marrow: Results in erythrocyte production
Myeloid neoplasms
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-Myeloproliferative diseases
-Myelodysplastic/proliferative diseases
-Myelodysplastic syndromes
-Acute myeloid leukemia (AML)
Type I Hypersensitivity Pathogenesis
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1-184 of 184
Click a definition to match it with a term
Anaphylaxis
Give this one a try later!
Most life-threatening reaction; occurs in very small number of highly
allergic individuals
Type IV Hypersensitivity
,Give this one a try later!
Delayed hypersensitivity
- Tissue damage resulting from a delayed cellular reaction to an antigen
-No primary antibody involvement
Principal mediators (Lymphocytes & Macrophages)
Hemolytic Disease of the Newborn
Give this one a try later!
Fetal RBCs cross placenta, stimulate
production of maternal antibodies against
Rh+ antigen on fetal RBC not inherited
from mother ** (mother: Rh- blood type)
Maternal antibodies cross into the fetal
circulation causing destruction of fetal cells
-ABO incompatibility most common
-Rh incompatibility more clinically relevant **
Hairy Cell Leukemia Pathogenesis and Clinical Manifestations
Give this one a try later!
Hairy cells in peripheral blood
Reduced numbers in granulocytes, platelets, red blood cells
Splenomegaly (90%)
Final stage Hemostasis
,Give this one a try later!
clot retraction
Hairy Cell Leukemia
Give this one a try later!
-Rare, chronic type of leukemia
-2% of adult leukemia but highly treatable
-Median age of presentation: 55 years; 5:1 predominance of males
-B-cell phenotype
-Peculiar cells with hairlike projections on their surface
Tissue Deposition: Intermediate sized complexes
Give this one a try later!
-Do not fit complement /bind w/ RBCs well
-Not removed by mononuclear phagocyte system well
Transient hypogammaglobulinemia
Give this one a try later!
, B-cell disorder.
Self-limiting condition.
Infant slow to acquire normal immunoglobulin levels.
Hematopoiesis
Give this one a try later!
stem cells---reticulocytes(erythroblasts)---mature
red blood cells(erythrocytes)
-Erythropoietin/EPO: Made in kidney (adult)** Fetus and newborn: Liver
and kidney
Renal disease causes anemia
-Functions in bone marrow: Results in erythrocyte production
Myeloid neoplasms
Give this one a try later!
-Myeloproliferative diseases
-Myelodysplastic/proliferative diseases
-Myelodysplastic syndromes
-Acute myeloid leukemia (AML)
Type I Hypersensitivity Pathogenesis
Give this one a try later!
