NR565 WEEK 1 CHAPTERS 2, 7, 8 STUDY QUESTIONS
WITH CORRECT ANSWERS 2026
A patient's nutritional intake and laboratory results reflect hypoalbuminemia. This is critical to
prescribing because: - CORRECT ANSWER -Distribution of drugs to target tissue may be affected.
Drugs that have a significant first-pass effect: - CORRECT ANSWER -Are rapidly metabolized by
the liver and may have little if any desired action
The route of excretion of a volatile drug will likely be the: - CORRECT ANSWER -Lungs
Medroxyprogesterone (Depo Provera) is prescribed intramuscularly (IM) to create a storage
reservoir of the drug. Storage reservoirs: - CORRECT ANSWER -Increase the length of time a
drug is available and active
The NP chooses to give cephalexin every 8 hours based on knowledge of the drug's: - CORRECT
ANSWER -Biological half-life
Azithromycin dosing requires that the first day's dosage be twice those of the other 4 days of
the prescription. This is considered a loading dose. A loading dose: - CORRECT ANSWER -Rapidly
achieves drug levels in the therapeutic range
The point in time on the drug concentration curve that indicates the first sign of a therapeutic
effect is the: - CORRECT ANSWER -Onset of action
Phenytoin requires that a trough level be drawn. Peak and trough levels are done: - CORRECT
ANSWER -To determine if a drug is in the therapeutic range
, A laboratory result indicates that the peak level for a drug is above the minimum toxic
concentration. This means that the: - CORRECT ANSWER -Concentration will produce an adverse
response
Drugs that are receptor agonists may demonstrate what property? - CORRECT ANSWER -
Desensitization or downregulation with continuous use
Drugs that are receptor antagonists, such as beta blockers, may cause: - CORRECT ANSWER -An
exaggerated response if abruptly discontinued
Factors that affect gastric drug absorption include: - CORRECT ANSWER -Lipid solubility of the
drug
Drugs administered via IV: - CORRECT ANSWER -Begin distribution into the body immediately
When a medication is added to a regimen for a synergistic effect, the combined effect of the
drugs is: - CORRECT ANSWER -Greater than the sum of the effects of each drug individually
Which of the following statements about bioavailability is true?
1. Bioavailability issues are especially important for drugs with narrow therapeutic ranges or
sustained-release mechanisms.
2. All brands of a drug have the same bioavailability.
3. Drugs that are administered more than once a day have greater bioavailability than drugs
given once daily.
4. Combining an active drug with an inert substance does not affect bioavailability - CORRECT
ANSWER -1. Bioavailability issues are especially important for drugs with narrow therapeutic
ranges or sustained-release mechanisms.
WITH CORRECT ANSWERS 2026
A patient's nutritional intake and laboratory results reflect hypoalbuminemia. This is critical to
prescribing because: - CORRECT ANSWER -Distribution of drugs to target tissue may be affected.
Drugs that have a significant first-pass effect: - CORRECT ANSWER -Are rapidly metabolized by
the liver and may have little if any desired action
The route of excretion of a volatile drug will likely be the: - CORRECT ANSWER -Lungs
Medroxyprogesterone (Depo Provera) is prescribed intramuscularly (IM) to create a storage
reservoir of the drug. Storage reservoirs: - CORRECT ANSWER -Increase the length of time a
drug is available and active
The NP chooses to give cephalexin every 8 hours based on knowledge of the drug's: - CORRECT
ANSWER -Biological half-life
Azithromycin dosing requires that the first day's dosage be twice those of the other 4 days of
the prescription. This is considered a loading dose. A loading dose: - CORRECT ANSWER -Rapidly
achieves drug levels in the therapeutic range
The point in time on the drug concentration curve that indicates the first sign of a therapeutic
effect is the: - CORRECT ANSWER -Onset of action
Phenytoin requires that a trough level be drawn. Peak and trough levels are done: - CORRECT
ANSWER -To determine if a drug is in the therapeutic range
, A laboratory result indicates that the peak level for a drug is above the minimum toxic
concentration. This means that the: - CORRECT ANSWER -Concentration will produce an adverse
response
Drugs that are receptor agonists may demonstrate what property? - CORRECT ANSWER -
Desensitization or downregulation with continuous use
Drugs that are receptor antagonists, such as beta blockers, may cause: - CORRECT ANSWER -An
exaggerated response if abruptly discontinued
Factors that affect gastric drug absorption include: - CORRECT ANSWER -Lipid solubility of the
drug
Drugs administered via IV: - CORRECT ANSWER -Begin distribution into the body immediately
When a medication is added to a regimen for a synergistic effect, the combined effect of the
drugs is: - CORRECT ANSWER -Greater than the sum of the effects of each drug individually
Which of the following statements about bioavailability is true?
1. Bioavailability issues are especially important for drugs with narrow therapeutic ranges or
sustained-release mechanisms.
2. All brands of a drug have the same bioavailability.
3. Drugs that are administered more than once a day have greater bioavailability than drugs
given once daily.
4. Combining an active drug with an inert substance does not affect bioavailability - CORRECT
ANSWER -1. Bioavailability issues are especially important for drugs with narrow therapeutic
ranges or sustained-release mechanisms.
