Pn 4006 complete set of newly updated exam questions and verified answers;
300 QUESTIONS AND ANSWERS
1. What do we check for when doing blood transfusion? - ANSWER Cross check blood
product. Monitor the transfusion for reaction.
2. What can LPN's do during a blood transfusion? - ANSWER LPN's can double sign when
giving blood. 2 signatures required.
3. Antibiotic first or blood first during transfusion? - ANSWER Both at same time if they
have separate lines.
4. What is the maximum time limit for completing a blood transfusion? - ANSWER 4 hours
maximum to prevent bacterial contamination.
5. What temperature should blood products be stored at? - ANSWER 1-6°C (34-43°F) in
blood bank refrigerator.
6. How long can blood be out of refrigeration before it must be returned? - ANSWER 30
minutes maximum before transfusion must begin.
7. What vital signs must be taken before blood transfusion? - ANSWER Temperature,
pulse, respirations, blood pressure, and oxygen saturation.
8. How often should vital signs be monitored during transfusion? - ANSWER Every 15
minutes for first hour, then every 30 minutes.
9. What is the first sign of a transfusion reaction? - ANSWER Change in vital signs,
especially temperature elevation.
10. What should you do if a transfusion reaction is suspected? - ANSWER Stop transfusion
immediately, maintain IV access with normal saline, notify physician.
11. What blood type is the universal donor? - ANSWER Type O negative (O-).
12. What blood type is the universal recipient? - ANSWER Type AB positive (AB+).
1|Page
,Pn 4006 complete set of newly updated exam questions and verified answers;
300 QUESTIONS AND ANSWERS
13. Can type A blood receive type B blood? - ANSWER No, incompatible and will cause
hemolytic reaction.
14. What happens if incompatible blood is transfused? - ANSWER Hemolytic reaction,
hemolysis, kidney failure, shock, death.
15. What is the Rh factor? - ANSWER Protein on red blood cells; positive if present,
negative if absent.
16. Can Rh negative patient receive Rh positive blood? - ANSWER No, will develop
antibodies and future reactions.
17. What is crossmatching? - ANSWER Testing patient's blood with donor blood to ensure
compatibility.
18. How long is a crossmatch valid? - ANSWER 72 hours from time of collection.
19. What is type and screen? - ANSWER Determines patient's blood type and screens for
antibodies.
20. What does ABO incompatibility cause? - ANSWER Immediate hemolytic transfusion
reaction.
21. What are signs of acute hemolytic reaction? - ANSWER Fever, chills, back pain, chest
pain, dyspnea, hypotension.
22. What is febrile non-hemolytic reaction? - ANSWER Fever and chills without hemolysis,
most common reaction.
23. How do you treat febrile reaction? - ANSWER Stop transfusion, give antipyretics,
monitor vital signs.
24. What is allergic transfusion reaction? - ANSWER Urticaria, itching, rash from plasma
proteins.
2|Page
, Pn 4006 complete set of newly updated exam questions and verified answers;
300 QUESTIONS AND ANSWERS
25. How do you treat mild allergic reaction? - ANSWER Give antihistamines, may continue
transfusion if mild.
26. What is anaphylactic reaction? - ANSWER Severe allergic reaction with bronchospasm,
shock, respiratory distress.
27. What is TRALI? - ANSWER Transfusion-Related Acute Lung Injury causing pulmonary
edema.
28. What causes circulatory overload? - ANSWER Transfusing too rapidly or too much
volume.
29. Signs of circulatory overload? - ANSWER Dyspnea, crackles, jugular vein distention,
hypertension.
30. What is delayed hemolytic reaction? - ANSWER Occurs 3-10 days post-transfusion,
gradual hemolysis.
31. What must be verified before starting transfusion? - ANSWER Patient identity, blood
type, crossmatch, expiration date.
32. Who must verify blood product information? - ANSWER Two licensed nurses must
double-check all information.
33. What patient identifiers are required? - ANSWER Full name, date of birth, medical
record number, blood bank number.
34. What IV gauge is needed for blood transfusion? - ANSWER 18-20 gauge catheter
minimum for adequate flow.
35. What solution is compatible with blood products? - ANSWER Only normal saline (0.9%
NaCl).
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300 QUESTIONS AND ANSWERS
1. What do we check for when doing blood transfusion? - ANSWER Cross check blood
product. Monitor the transfusion for reaction.
2. What can LPN's do during a blood transfusion? - ANSWER LPN's can double sign when
giving blood. 2 signatures required.
3. Antibiotic first or blood first during transfusion? - ANSWER Both at same time if they
have separate lines.
4. What is the maximum time limit for completing a blood transfusion? - ANSWER 4 hours
maximum to prevent bacterial contamination.
5. What temperature should blood products be stored at? - ANSWER 1-6°C (34-43°F) in
blood bank refrigerator.
6. How long can blood be out of refrigeration before it must be returned? - ANSWER 30
minutes maximum before transfusion must begin.
7. What vital signs must be taken before blood transfusion? - ANSWER Temperature,
pulse, respirations, blood pressure, and oxygen saturation.
8. How often should vital signs be monitored during transfusion? - ANSWER Every 15
minutes for first hour, then every 30 minutes.
9. What is the first sign of a transfusion reaction? - ANSWER Change in vital signs,
especially temperature elevation.
10. What should you do if a transfusion reaction is suspected? - ANSWER Stop transfusion
immediately, maintain IV access with normal saline, notify physician.
11. What blood type is the universal donor? - ANSWER Type O negative (O-).
12. What blood type is the universal recipient? - ANSWER Type AB positive (AB+).
1|Page
,Pn 4006 complete set of newly updated exam questions and verified answers;
300 QUESTIONS AND ANSWERS
13. Can type A blood receive type B blood? - ANSWER No, incompatible and will cause
hemolytic reaction.
14. What happens if incompatible blood is transfused? - ANSWER Hemolytic reaction,
hemolysis, kidney failure, shock, death.
15. What is the Rh factor? - ANSWER Protein on red blood cells; positive if present,
negative if absent.
16. Can Rh negative patient receive Rh positive blood? - ANSWER No, will develop
antibodies and future reactions.
17. What is crossmatching? - ANSWER Testing patient's blood with donor blood to ensure
compatibility.
18. How long is a crossmatch valid? - ANSWER 72 hours from time of collection.
19. What is type and screen? - ANSWER Determines patient's blood type and screens for
antibodies.
20. What does ABO incompatibility cause? - ANSWER Immediate hemolytic transfusion
reaction.
21. What are signs of acute hemolytic reaction? - ANSWER Fever, chills, back pain, chest
pain, dyspnea, hypotension.
22. What is febrile non-hemolytic reaction? - ANSWER Fever and chills without hemolysis,
most common reaction.
23. How do you treat febrile reaction? - ANSWER Stop transfusion, give antipyretics,
monitor vital signs.
24. What is allergic transfusion reaction? - ANSWER Urticaria, itching, rash from plasma
proteins.
2|Page
, Pn 4006 complete set of newly updated exam questions and verified answers;
300 QUESTIONS AND ANSWERS
25. How do you treat mild allergic reaction? - ANSWER Give antihistamines, may continue
transfusion if mild.
26. What is anaphylactic reaction? - ANSWER Severe allergic reaction with bronchospasm,
shock, respiratory distress.
27. What is TRALI? - ANSWER Transfusion-Related Acute Lung Injury causing pulmonary
edema.
28. What causes circulatory overload? - ANSWER Transfusing too rapidly or too much
volume.
29. Signs of circulatory overload? - ANSWER Dyspnea, crackles, jugular vein distention,
hypertension.
30. What is delayed hemolytic reaction? - ANSWER Occurs 3-10 days post-transfusion,
gradual hemolysis.
31. What must be verified before starting transfusion? - ANSWER Patient identity, blood
type, crossmatch, expiration date.
32. Who must verify blood product information? - ANSWER Two licensed nurses must
double-check all information.
33. What patient identifiers are required? - ANSWER Full name, date of birth, medical
record number, blood bank number.
34. What IV gauge is needed for blood transfusion? - ANSWER 18-20 gauge catheter
minimum for adequate flow.
35. What solution is compatible with blood products? - ANSWER Only normal saline (0.9%
NaCl).
3|Page
