2026 QUESTIONS WITH ANSWERS GRADED
A+
◉ Antimicrobials. Answer: Used in 350 AD (even though they didn't
know how the chemical worked)
◉ Antimicrobials were mostly obtained through. Answer: consumption
of plants and fermented products (i.e. beer)
◉ First drugs were developed by science in. Answer: early 1900s
◉ Paul Ehrlich. Answer: scanned through 600 arsenic compounds to
find cure for syphilis without killing host
◉ Syphilis compound was derived from. Answer: Treponema pallidum
and established modern drug discovery methods
◉ Joseph Klarer, Fritz Mietzch, and Gerhard Domagk. Answer: used
synthetic dye, prontosil, to treat strep infections
, ◉ The first synthetic antimicrobial was. Answer: Prontosil; opened door
for all "sulfa" drugs
◉ Alex Fleming. Answer: accidentally discovered antibiotic from
Penicillum notatum growing on bacterial agar plate
◉ Penicillum. Answer: 1st natural antibiotic
◉ Bactericidal. Answer: kills microbes
◉ Bacteriostatic. Answer: halts growth of microbes
◉ Narrow Spectrum of Chemotherapy Drugs. Answer: BEST CHOICE;
targets specific group of microbes
◉ Broad Spectrum of Chemotherapy Drugs. Answer: targets wide
variety
◉ Downside to Broad Spectrum. Answer: superinfection
◉ Superinfection. Answer: 1) Normal microbiota keeps opportunistic
pathogens in check
2) Broad-spectrum antibiotics kill nonresistant cells