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Biology
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Biology) H0220
2025 OCR AS Level Biology B (Advancing Biology)
H022/02 Biology in depth
Verified Question paper with Marking Scheme Attached
Oxford Cambridge and RSA
Thursday 22 May 2025 – Morning
AS Level Biology B (Advancing Biology)
H022/02 Biology in depth
Time allowed: 1 hour 30 minutes
You can use:
• a scientific or graphical calculator
• a ruler (cm/mm)
Please write clearly in black ink. Do not write in the barcodes.
Centre number Candidate number
First name(s)
Last name
INSTRUCTIONS
• Use black ink. You can use an HB pencil, but only for graphs and diagrams.
• Write your answer to each question in the space provided. If you need extra space use the lined
pages at the end of this booklet. The question numbers must be clearly shown.
• Answer all the questions.
• Where appropriate, your answer should be supported with working. Marks might be given
for a correct method, even if your answer is wrong.
INFORMATION
• The total mark for this paper is 70.
• The marks for each question are shown in brackets [ ].
• Quality of extended response will be assessed in questions marked with an asterisk (*).
• This document has 24 pages.
ADVICE
• Read each question carefully before you start your answer.
© OCR 2025 [601/4721/0] OCR is an exempt Charity
DC (LK/CB) 329634/3 Turn over
1 OCR A/AS Page 1
,S
uestion
Level Paper
question
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A/AS=2025
paper,
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Biology
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Question
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Attached.pdf
Answers
Biology) H0220
2
1
(a) The mammalian circulatory system is described as a closed double circulatory system.
(i) Explain what is meant by a closed circulatory system.
..........................................................................................................................................................
. .................................................................................................................................................................... [1]
(ii) The diagram below shows the circulatory system of a frog.
Capillaries in the lungs and skin
right left
side side
Capillaries in the muscles
Blood leaving the heart of a frog is less oxygenated than blood leaving the heart of a mammal.
Explain why blood leaving the heart of a frog is less oxygenated than blood leaving the heart of a mammal.
..........................................................................................................................................................
..........................................................................................................................................................
..........................................................................................................................................................
..........................................................................................................................................................
. .................................................................................................................................................................... [2]
© OCR 2025
2 OCR A/AS Page 2
,S
uestion
Level Paper
question
OCR with
A/AS=2025
paper,
Exam-Ready
including
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Biology
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Biology) H0220
3
(b) The image below shows a section through the wall of an artery.
X Y
×500
Calculate the actual width of the artery wall between points X and Y. Give your
answer to the nearest whole number.
Actual width =..............................................................μm [2]
© OCR 2025 Turn over
3 OCR A/AS Page 3
,S
uestion
Level Paper
question
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A/AS=2025
paper,
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Biology
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Biology) H0220
4
(c) * Describe how the tissues in the artery wall are adapted to their function.
..........................................................................................................................................................
..........................................................................................................................................................
..........................................................................................................................................................
..........................................................................................................................................................
..........................................................................................................................................................
..........................................................................................................................................................
..........................................................................................................................................................
..........................................................................................................................................................
..........................................................................................................................................................
..........................................................................................................................................................
..........................................................................................................................................................
..........................................................................................................................................................
..........................................................................................................................................................
..........................................................................................................................................................
. .................................................................................................................................................................... [6]
Extra answer space if required.
..........................................................................................................................................................
..........................................................................................................................................................
..........................................................................................................................................................
..........................................................................................................................................................
..........................................................................................................................................................
© OCR 2025
4 OCR A/AS Page 4
uestion
Level Paper
question
OCR with
A/AS=2025
paper,
Exam-Ready
including
OCR ASExaminer
theLevel
complete
Biology
MarkQuestion
Scheme.
B (Advancing
Paper
Covers
with
Biology)
allExam-Ready
examinable
H02202content
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Examiner
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Verified
Answers2025
Question
Covers allOCR
paper
examinable
AS
with
Level
Marking
content
Biology
Scheme
with
B (Advancing
Verified
Attached.pdf
Answers
Biology) H0220
2025 OCR AS Level Biology B (Advancing Biology)
H022/02 Biology in depth
Verified Question paper with Marking Scheme Attached
Oxford Cambridge and RSA
Thursday 22 May 2025 – Morning
AS Level Biology B (Advancing Biology)
H022/02 Biology in depth
Time allowed: 1 hour 30 minutes
You can use:
• a scientific or graphical calculator
• a ruler (cm/mm)
Please write clearly in black ink. Do not write in the barcodes.
Centre number Candidate number
First name(s)
Last name
INSTRUCTIONS
• Use black ink. You can use an HB pencil, but only for graphs and diagrams.
• Write your answer to each question in the space provided. If you need extra space use the lined
pages at the end of this booklet. The question numbers must be clearly shown.
• Answer all the questions.
• Where appropriate, your answer should be supported with working. Marks might be given
for a correct method, even if your answer is wrong.
INFORMATION
• The total mark for this paper is 70.
• The marks for each question are shown in brackets [ ].
• Quality of extended response will be assessed in questions marked with an asterisk (*).
• This document has 24 pages.
ADVICE
• Read each question carefully before you start your answer.
© OCR 2025 [601/4721/0] OCR is an exempt Charity
DC (LK/CB) 329634/3 Turn over
1 OCR A/AS Page 1
,S
uestion
Level Paper
question
OCR with
A/AS=2025
paper,
Exam-Ready
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OCR ASExaminer
theLevel
complete
Biology
MarkQuestion
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B (Advancing
Paper
Covers
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Question
Covers allOCR
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Scheme
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Verified
Attached.pdf
Answers
Biology) H0220
2
1
(a) The mammalian circulatory system is described as a closed double circulatory system.
(i) Explain what is meant by a closed circulatory system.
..........................................................................................................................................................
. .................................................................................................................................................................... [1]
(ii) The diagram below shows the circulatory system of a frog.
Capillaries in the lungs and skin
right left
side side
Capillaries in the muscles
Blood leaving the heart of a frog is less oxygenated than blood leaving the heart of a mammal.
Explain why blood leaving the heart of a frog is less oxygenated than blood leaving the heart of a mammal.
..........................................................................................................................................................
..........................................................................................................................................................
..........................................................................................................................................................
..........................................................................................................................................................
. .................................................................................................................................................................... [2]
© OCR 2025
2 OCR A/AS Page 2
,S
uestion
Level Paper
question
OCR with
A/AS=2025
paper,
Exam-Ready
including
OCR ASExaminer
theLevel
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Biology
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Paper
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Question
Covers allOCR
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AS
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Attached.pdf
Answers
Biology) H0220
3
(b) The image below shows a section through the wall of an artery.
X Y
×500
Calculate the actual width of the artery wall between points X and Y. Give your
answer to the nearest whole number.
Actual width =..............................................................μm [2]
© OCR 2025 Turn over
3 OCR A/AS Page 3
,S
uestion
Level Paper
question
OCR with
A/AS=2025
paper,
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Biology
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Attached.pdf
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Biology) H0220
4
(c) * Describe how the tissues in the artery wall are adapted to their function.
..........................................................................................................................................................
..........................................................................................................................................................
..........................................................................................................................................................
..........................................................................................................................................................
..........................................................................................................................................................
..........................................................................................................................................................
..........................................................................................................................................................
..........................................................................................................................................................
..........................................................................................................................................................
..........................................................................................................................................................
..........................................................................................................................................................
..........................................................................................................................................................
..........................................................................................................................................................
..........................................................................................................................................................
. .................................................................................................................................................................... [6]
Extra answer space if required.
..........................................................................................................................................................
..........................................................................................................................................................
..........................................................................................................................................................
..........................................................................................................................................................
..........................................................................................................................................................
© OCR 2025
4 OCR A/AS Page 4
