Advanced Pharmacology Exam 1 Final Exam Newest Actual
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Prescription writing: required pt and prescriber info - ANSWERS--
Patient's name and full address
Date of prescription
Prescriber's full name, address, and phone number
Prescriber's DEA # if controlled substance
Prescription writing: required drug info - ANSWERS--Name (don't
abbreviate)
Strength and vehicle
Dosage
Route of administration
Directions (Sig) for taking the med: frequency, timing, details specific
to drug
Amount to be dispensed
Refills
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Critical Rx Information? - ANSWERS--DAW vs generic, refill #, dose
form, length of therapy/quantity, pt Ax, date of Rx, route, signature,
DEA #
"Rational" Prescribing Process, WHO - ANSWERS--Choose a rational
treatment
Selection of P-drugs (Personal drugs)
Treating the pt (select, Rx, monitor)
Keeping up-to-date
What are P-drugs? - ANSWERS--P(ersonal) drugs - those that you are
going to prescribe regularly and with which you become familiar
Steps of Rational Prescribing - ANSWERS--Define the pt's problem
Specify the therapeutic objective
Choose Tx
Verify: efficacy, safety, suitability, cost
Start Tx (write a clear Rx)
Educate! Give inform instructions, warnings
Monitor treatment
What is DAW in prescribing? - ANSWERS--Dispense as written
"Rights" of a prescription - ANSWERS--Patient
Medication
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Dose
Route
Dose schedule
Does this make sense for this drug, patient, situation?
Pharmacokinetics - ANSWERS--How the body affects a drug
Pharmacodynamics - ANSWERS--How a drug affects the body -
effects that occur at the cellular and systemic levels
Pharmacogenomics - ANSWERS--General study of how one's
individual genetic variation affects drug behavior
Four components of pharmacokinetics - ANSWERS--ADME -
absorption, distribution, metabolism, excretion
Absorption - ANSWERS--How (well) does the body uptake the drug?
Distribution - ANSWERS--Transportation of the drug to the site of
action
How (well) is the drug carried to the site of action?
Elimination - ANSWERS--How (well) is the drug cleared from the
body?
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All types of absorption are affected by... - ANSWERS--Drug properties
(molecular weight, lipid solubility) pKa, drug formulation,
disintegration time, dissolution rate)
Enteral Absorption - GI tract - affected by? (4 things) - ANSWERS--
Blood flow to area of absorption
First pass effect
Cellular membrane permeability (passive vs. active)
GI motility (absence/presence of food in stomach, other drugs)
Parenteral Absorption - affected by? (2 things) - ANSWERS--Blood
flow to area of absorption
Cell membrane permeability (passive vs. active transport)
Bioavailability - ANSWERS--Percentage of a drug that reaches the
systemic circulation
Ex: IV route = 100% bioavailability
First pass effect - ANSWERS--PO drug that is absorbed in the GI tract
and metabolized via liver before reaching systemic circulation
Distribution is dependent upon... (3 things) - ANSWERS--Route of
administration
Blood flow
Solubility of drug (lipid/water)