HESI PHARMACOLOGY PRACTICAL TEST EXAM 2026 WITH
ACTUAL CORRECT QUESTIONS AND ANSWERS|CURRENTLY
TESTING VERSION|ALREADY GRADED A+|GUARANTEED PASS
The nurse reviews the new prescription, phenelzine (Nardil), a monoamine oxidase inhibitor
(MAOI), for a client with depression on the psychiatric unit. Which information is most
important for the nurse to assess?
A. Consumption of any alcohol or tyramine rich foods
B. Reports of nausea or vomiting
C. Therapeutic serum drug levels
D. Blood pressure and pulse prior to taking each dose
The nurse is administering haloperidol 0.5 mg IM PRN to a client for the first time. What side
effects should the nurse assess the client during the initial dose?
A. Bradykinesia
B. Dystonia
C. Somatization
D. Akathisia
While reviewing the client's electronic medical record (EMR), the nurse assesses a client who is
at risk for a possible interaction with an over-the-counter (OTC) decongestant. Which client
health history should the nurse report to the health care provider concerning the OTC
medication? (Select all that apply)
A. Type 1 diabetes mellitus (DM)
B. Closed angle glaucoma
C. Chronic hypertension
D. Rheumatoid arthritis
E. Crohn's disease
A client prescribed ipratropium reports nausea, blurred vision, headaches, and insomnia after
using the inhaler. Which action should the nurse implement first?
A. Withhold the medication and report symptoms and vital signs to the healthcare provider
B. Give PRN medication for nausea and vomiting and evaluate client in 30 minutes
C. reassure client that the ipratropium given will alleviate the symptoms
D. Delay administration of ipratropium until the next maintenance medication is scheduled
1
,A client diagnosed with multiple sclerosis is experiencing profound weakness, blurry vision, and
shooting pains in both legs. Which medication is considered the best course of treatment for the
nurse to administer?
A. High dose methylprednisolone intravenously
B. Baclofen three times a day
C. Broad spectrum antibiotic coverage orally
D. Immunomodulatory drug therapy periodically
The nurse administers 30 mL of lactulose for a client with stage 2 hepatic encephalopathy. Which
assessment finding would indicate the medication is being therapeutic?
A. A decrease in blood ammonia levels
B. A softening in the stools
C. An increase in glucose absorption
D. A suppression of gut acidification
The nurse is teaching a client who is newly diagnosed with type 1 diabetes about neutral
protamine Hagedor (NPH) insulin. Which statement by the client indicates an understanding of
how the medication works?
A. It facilitates the transport of glucose into the cells
B. It stimulates the function of beta cells in the pancreas
C. It increases the intracellular receptor site sensitivity
D. It delays the carbohydrate digestion and absorption
The nurse should withhold which medication if a client reports nausea, vomiting, and diarrhea?
A. Colchicine (Mitigare, Colcrys)
B. Erythromycin (E-mycin)
C. Naproxen (Aleve, Naprosyn)
D. Labetalol (Normodyne)
A client newly prescribed esomeprazole for gastroesophageal reflux disease (GERD) asks the
nurse how the medication will help. Which is the best explanation to provide the client?
A. It will promote rapid tissue healing
B. It will increase gastric emptying
C. It will improve esophageal peristalsis
D. It will neutralize gastric secretions
A nurse is providing medication education for a client prescribed a beta-blocking agent for
treatment of glaucoma. Which statement by the client demonstrates an understanding of the
2
, mechanism of the medication?
A. It inhibits the aqueous humor production
B. It enhances the aqueous humor outflow
C. It increases the intraocular pressure
D. It prevents extraocular infection
A nurse is planning a teaching session for a client newly prescribed a miotic drug for the
treatment of glaucoma. Which information should the nurse include in the teaching session?
A. The medication enhances the aqueous humor outflow
B. The medication inhibits the aqueous humor production
C. The medication dilates the pupils
D. The medication prevents extraocular infection
The healthcare provider (HCP) prescribes a medication for an older adult client who is reporting
insomnia, and the HCP instructs the client to return in two weeks. The nurse should question
which prescription?
A Zolpidem (Ambien) 10 milligrams orally at bedtime
B. Eszopiclone (Lunesta) 10 milligrams orally at bedtime
C. Temazepam (Restoril) 7.5 milligrams orally at bedtime
D. Ramelteon (Rozerem) 8 milligrams orally at bedtime
A client is diagnosed with peptic ulcer disease and receives a prescription for esomeprazole
(Nexium) 20 mg capsule daily. When providing this client with discharge teaching, the nurse
should include which instruction?
A. Drink fluids between meals to relieve gastric distress
B. Monitor for an increase in blood pressure during therapy
C. Dissolve capsule contents in fruit juice for easier ingestion
D. Take at same time each day one hour before eating a meal
A client receives a new prescription for ciprofloxacin (Cipro), a synthetic quinolone. When
teaching about this drug, which information in the client history requires special emphasis by the
nurse?
A. Snacks on dairy products such as yogurt or ice cream
B. Previously had a mild allergic reaction to a cephalosporin
C. Consumes alcoholic drinks occasionally on the weekends
D. works twenty hours a week as a lifeguard at the local pool
3
ACTUAL CORRECT QUESTIONS AND ANSWERS|CURRENTLY
TESTING VERSION|ALREADY GRADED A+|GUARANTEED PASS
The nurse reviews the new prescription, phenelzine (Nardil), a monoamine oxidase inhibitor
(MAOI), for a client with depression on the psychiatric unit. Which information is most
important for the nurse to assess?
A. Consumption of any alcohol or tyramine rich foods
B. Reports of nausea or vomiting
C. Therapeutic serum drug levels
D. Blood pressure and pulse prior to taking each dose
The nurse is administering haloperidol 0.5 mg IM PRN to a client for the first time. What side
effects should the nurse assess the client during the initial dose?
A. Bradykinesia
B. Dystonia
C. Somatization
D. Akathisia
While reviewing the client's electronic medical record (EMR), the nurse assesses a client who is
at risk for a possible interaction with an over-the-counter (OTC) decongestant. Which client
health history should the nurse report to the health care provider concerning the OTC
medication? (Select all that apply)
A. Type 1 diabetes mellitus (DM)
B. Closed angle glaucoma
C. Chronic hypertension
D. Rheumatoid arthritis
E. Crohn's disease
A client prescribed ipratropium reports nausea, blurred vision, headaches, and insomnia after
using the inhaler. Which action should the nurse implement first?
A. Withhold the medication and report symptoms and vital signs to the healthcare provider
B. Give PRN medication for nausea and vomiting and evaluate client in 30 minutes
C. reassure client that the ipratropium given will alleviate the symptoms
D. Delay administration of ipratropium until the next maintenance medication is scheduled
1
,A client diagnosed with multiple sclerosis is experiencing profound weakness, blurry vision, and
shooting pains in both legs. Which medication is considered the best course of treatment for the
nurse to administer?
A. High dose methylprednisolone intravenously
B. Baclofen three times a day
C. Broad spectrum antibiotic coverage orally
D. Immunomodulatory drug therapy periodically
The nurse administers 30 mL of lactulose for a client with stage 2 hepatic encephalopathy. Which
assessment finding would indicate the medication is being therapeutic?
A. A decrease in blood ammonia levels
B. A softening in the stools
C. An increase in glucose absorption
D. A suppression of gut acidification
The nurse is teaching a client who is newly diagnosed with type 1 diabetes about neutral
protamine Hagedor (NPH) insulin. Which statement by the client indicates an understanding of
how the medication works?
A. It facilitates the transport of glucose into the cells
B. It stimulates the function of beta cells in the pancreas
C. It increases the intracellular receptor site sensitivity
D. It delays the carbohydrate digestion and absorption
The nurse should withhold which medication if a client reports nausea, vomiting, and diarrhea?
A. Colchicine (Mitigare, Colcrys)
B. Erythromycin (E-mycin)
C. Naproxen (Aleve, Naprosyn)
D. Labetalol (Normodyne)
A client newly prescribed esomeprazole for gastroesophageal reflux disease (GERD) asks the
nurse how the medication will help. Which is the best explanation to provide the client?
A. It will promote rapid tissue healing
B. It will increase gastric emptying
C. It will improve esophageal peristalsis
D. It will neutralize gastric secretions
A nurse is providing medication education for a client prescribed a beta-blocking agent for
treatment of glaucoma. Which statement by the client demonstrates an understanding of the
2
, mechanism of the medication?
A. It inhibits the aqueous humor production
B. It enhances the aqueous humor outflow
C. It increases the intraocular pressure
D. It prevents extraocular infection
A nurse is planning a teaching session for a client newly prescribed a miotic drug for the
treatment of glaucoma. Which information should the nurse include in the teaching session?
A. The medication enhances the aqueous humor outflow
B. The medication inhibits the aqueous humor production
C. The medication dilates the pupils
D. The medication prevents extraocular infection
The healthcare provider (HCP) prescribes a medication for an older adult client who is reporting
insomnia, and the HCP instructs the client to return in two weeks. The nurse should question
which prescription?
A Zolpidem (Ambien) 10 milligrams orally at bedtime
B. Eszopiclone (Lunesta) 10 milligrams orally at bedtime
C. Temazepam (Restoril) 7.5 milligrams orally at bedtime
D. Ramelteon (Rozerem) 8 milligrams orally at bedtime
A client is diagnosed with peptic ulcer disease and receives a prescription for esomeprazole
(Nexium) 20 mg capsule daily. When providing this client with discharge teaching, the nurse
should include which instruction?
A. Drink fluids between meals to relieve gastric distress
B. Monitor for an increase in blood pressure during therapy
C. Dissolve capsule contents in fruit juice for easier ingestion
D. Take at same time each day one hour before eating a meal
A client receives a new prescription for ciprofloxacin (Cipro), a synthetic quinolone. When
teaching about this drug, which information in the client history requires special emphasis by the
nurse?
A. Snacks on dairy products such as yogurt or ice cream
B. Previously had a mild allergic reaction to a cephalosporin
C. Consumes alcoholic drinks occasionally on the weekends
D. works twenty hours a week as a lifeguard at the local pool
3
