EVOLVE HESI 1 PRACTICE
EXAM WITH RATIONALES
COMPLETE EXAM
PREPARATION UPDATED FOR
2026
Which condition is contraindicated for St. John's Wort herbal therapy? -
Answer--Dementia (St. John's Wort is used to treat anxiety)
other contraindicated for st. johns: schizophrenia, bipolar depression, Alzheimer's
Which condition is contraindicated for Bupropion? - Answer--Seizures
Which condition is contraindicated for Valerian? - Answer--Cardiac Disease
Which condition is contraindicated for ginseng herbal therapy? - Answer--Pregnancy
Which antidepressant medication is a selective monoamine oxidase-B inhibitor?
a. Selegiline
b. Phenelzine
,c. Isocarboxazid
d. Tranylcypromine - Answer--Selegiline is a a selective monoamine oxidase-B inhibitor.
The other medications are nonselective monoamine oxidase-A and B inhibitors.
Which response identified by the nurse is unrelated to an extrapyramidal tract effect? -
Answer--opisthotonos, oculogyric crisis, akathisia are all examples. Hypertension is
unrelated.
Extrapyramidal tracts: Originate in the brainstem, carrying motor fibres to the spinal
cord. They are responsible for the unconscious, reflexive or responsive control of
musculature, eg muscle tone, balance, posture and locomotion.
Zolipidem (Ambien) - Answer--Sedative/hypnotic; short use for INSOMNIA
o Can cause daytime sleepiness
o schedule 4 drug; risk for dependence
o avoid ETOH, barbiturates, opioids and other CNS depressants when taking
Semi-Fowler's Position - Answer--the head of the bed is raised 30 degrees; or the head
of the bed is raised 30 degrees and the knee portion is raised 15 degrees
Which body region is most at risk for pressure injury when the client is in semi-fowlers
position? - Answer--Sacrum
Which body region is most at risk for pressure injury when the client is in upright sitting
position? - Answer--Ischial spine
Which body region is most at risk for pressure injury when the client is in side lying
position? - Answer--Greater trochanter
What do neuroleptics do? - Answer--o it blocks dopamine
o treats schizophrenia, does not treat Parkinson's
o increases serotonin at post synaptic sites
Clozapine is used for what and poses a risk for what? - Answer--o antipsychotic
medication
o risk for development of agranulocytosis, especially when combined with SSRI (such
as prozac)
o monitor WBC
, In adolescents, the volume of solution required for an enema is: - Answer--500-750 mL
In infants, the volume of solution required for an enema is: - Answer--150-250 mL
warmed solution
Second generation antipsychotics may cause: - Answer--metabolic side effects such as
diabetes and dyslipiemia
clozapine is more effective than others
first generation antipsychotics may cause - Answer--extrapyramidal side effects
Which medication may lead to bruxism? - Answer--levomilnacipran
Which age related effects occur in the older client? - Answer--increased autoantibodies
Which age related effects DECREASE in the older client? - Answer--expression of IL-2
receptors, delayed hypersensitivity reaction, and primary/secondary antibody responses
Autoantibodies - Answer--Antibodies produced by B cells that mistakenly attack and
destroy "self" cells belonging to the patient; autoantibodies are the pathophysiologic
agent of most autoimmune disorders
mediastinoscopy - Answer--endoscopic visual examination of the mediastinum - a
suprasternal incision is made for inspection/ biopsy of lymph nodes
visual examination of the mediastinal structures, including the heart, trachea,
esophagus, bronchus, thymus, and lymph nodes
Trans bronchial biopsy - Answer--A pulmonologist performs a diagnostic bronchoscopy
with biopsy. The endoscope was introduced into the bronchus, and attachments were
used to perforate the bronchial wall. Tissue was obtained and submitted to the
pathologist, who identified it as "lung parenchyma." What type of biopsy was
performed?
tomography - Answer--radiographic image of a selected slice of tissue
isocarboxazid overdose (MAO overdose) - Answer--circulatory collapse
EXAM WITH RATIONALES
COMPLETE EXAM
PREPARATION UPDATED FOR
2026
Which condition is contraindicated for St. John's Wort herbal therapy? -
Answer--Dementia (St. John's Wort is used to treat anxiety)
other contraindicated for st. johns: schizophrenia, bipolar depression, Alzheimer's
Which condition is contraindicated for Bupropion? - Answer--Seizures
Which condition is contraindicated for Valerian? - Answer--Cardiac Disease
Which condition is contraindicated for ginseng herbal therapy? - Answer--Pregnancy
Which antidepressant medication is a selective monoamine oxidase-B inhibitor?
a. Selegiline
b. Phenelzine
,c. Isocarboxazid
d. Tranylcypromine - Answer--Selegiline is a a selective monoamine oxidase-B inhibitor.
The other medications are nonselective monoamine oxidase-A and B inhibitors.
Which response identified by the nurse is unrelated to an extrapyramidal tract effect? -
Answer--opisthotonos, oculogyric crisis, akathisia are all examples. Hypertension is
unrelated.
Extrapyramidal tracts: Originate in the brainstem, carrying motor fibres to the spinal
cord. They are responsible for the unconscious, reflexive or responsive control of
musculature, eg muscle tone, balance, posture and locomotion.
Zolipidem (Ambien) - Answer--Sedative/hypnotic; short use for INSOMNIA
o Can cause daytime sleepiness
o schedule 4 drug; risk for dependence
o avoid ETOH, barbiturates, opioids and other CNS depressants when taking
Semi-Fowler's Position - Answer--the head of the bed is raised 30 degrees; or the head
of the bed is raised 30 degrees and the knee portion is raised 15 degrees
Which body region is most at risk for pressure injury when the client is in semi-fowlers
position? - Answer--Sacrum
Which body region is most at risk for pressure injury when the client is in upright sitting
position? - Answer--Ischial spine
Which body region is most at risk for pressure injury when the client is in side lying
position? - Answer--Greater trochanter
What do neuroleptics do? - Answer--o it blocks dopamine
o treats schizophrenia, does not treat Parkinson's
o increases serotonin at post synaptic sites
Clozapine is used for what and poses a risk for what? - Answer--o antipsychotic
medication
o risk for development of agranulocytosis, especially when combined with SSRI (such
as prozac)
o monitor WBC
, In adolescents, the volume of solution required for an enema is: - Answer--500-750 mL
In infants, the volume of solution required for an enema is: - Answer--150-250 mL
warmed solution
Second generation antipsychotics may cause: - Answer--metabolic side effects such as
diabetes and dyslipiemia
clozapine is more effective than others
first generation antipsychotics may cause - Answer--extrapyramidal side effects
Which medication may lead to bruxism? - Answer--levomilnacipran
Which age related effects occur in the older client? - Answer--increased autoantibodies
Which age related effects DECREASE in the older client? - Answer--expression of IL-2
receptors, delayed hypersensitivity reaction, and primary/secondary antibody responses
Autoantibodies - Answer--Antibodies produced by B cells that mistakenly attack and
destroy "self" cells belonging to the patient; autoantibodies are the pathophysiologic
agent of most autoimmune disorders
mediastinoscopy - Answer--endoscopic visual examination of the mediastinum - a
suprasternal incision is made for inspection/ biopsy of lymph nodes
visual examination of the mediastinal structures, including the heart, trachea,
esophagus, bronchus, thymus, and lymph nodes
Trans bronchial biopsy - Answer--A pulmonologist performs a diagnostic bronchoscopy
with biopsy. The endoscope was introduced into the bronchus, and attachments were
used to perforate the bronchial wall. Tissue was obtained and submitted to the
pathologist, who identified it as "lung parenchyma." What type of biopsy was
performed?
tomography - Answer--radiographic image of a selected slice of tissue
isocarboxazid overdose (MAO overdose) - Answer--circulatory collapse
