Nurs 660 Exam 1
- Antipsychotic Medications with
Complete solutions
1. 3 classes of classical/ FGA:
1) phenothiazines
2) thioxanthenes
3) butyrophenones
2. prototypical SGA:
A n s w e r clozapine
3. chlorpromazine (THORAZINE): -lowest potentcy antipsychotic
-significant alpha-1 adrenergic blockade --> sedation, hypotention
-DA blockage in basal ganglia --> EPS
4. classic example of butyrophenone (FGA):
A n s w e r haloperidol (HALDOL)
5. haloperiol (HALDOL): -potent D2 blockade --> acute treatment of psychosis
, -high EPS, sedation
-less weight gain, anticholinergic ettects, hypotension
6. drug usually used to treat acute psychotic episodes:
A n s w e r haloperidol (HALDOL)
7. first generation antipsychotics block what receptors?:
A n s w e r block D2 receptors- therapeutic eflcacy correlates with D2 blockade
8. which antipsychotics alleviate mainly positive symptoms, and carry higher risk
of EPS and tardive dyskinesia with high doses and long-term use:
A n s w e r first gen- eration/ typical antipsychotics
-haloperidol
-chlorpromazine
9. SGA have greater affinity for which receptors: -aflnity for serotonin >> dopamine
10. SGA characteristics: -block more than 1 type of receptor
-help positive and negative sxs
-improve cognitive fx
-less EPS/TD
11. SGA/ atypical (5+):
1) clozapine (CLOZARIL)
2) risperidone (RIPERDAL)
- Antipsychotic Medications with
Complete solutions
1. 3 classes of classical/ FGA:
1) phenothiazines
2) thioxanthenes
3) butyrophenones
2. prototypical SGA:
A n s w e r clozapine
3. chlorpromazine (THORAZINE): -lowest potentcy antipsychotic
-significant alpha-1 adrenergic blockade --> sedation, hypotention
-DA blockage in basal ganglia --> EPS
4. classic example of butyrophenone (FGA):
A n s w e r haloperidol (HALDOL)
5. haloperiol (HALDOL): -potent D2 blockade --> acute treatment of psychosis
, -high EPS, sedation
-less weight gain, anticholinergic ettects, hypotension
6. drug usually used to treat acute psychotic episodes:
A n s w e r haloperidol (HALDOL)
7. first generation antipsychotics block what receptors?:
A n s w e r block D2 receptors- therapeutic eflcacy correlates with D2 blockade
8. which antipsychotics alleviate mainly positive symptoms, and carry higher risk
of EPS and tardive dyskinesia with high doses and long-term use:
A n s w e r first gen- eration/ typical antipsychotics
-haloperidol
-chlorpromazine
9. SGA have greater affinity for which receptors: -aflnity for serotonin >> dopamine
10. SGA characteristics: -block more than 1 type of receptor
-help positive and negative sxs
-improve cognitive fx
-less EPS/TD
11. SGA/ atypical (5+):
1) clozapine (CLOZARIL)
2) risperidone (RIPERDAL)
