CSO Exam - CH 18 Breast Cancer Questions with Correct Answers

CSO Exam - CH 18 Breast Cancer Questions v v v v v v v




with Correct Answers 2025/2026 v v v v




Breast cancer is the v v v v leading cause of cancer death - CORRECT ANSWER -2nd
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Majority of breast cancer is from cell lining
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ANSWER -milk ducts
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breast lobules v




There is a lower risk of death when breast cancer pt do this. - CORRECT ANSWER -PA -- nurses health
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study + collaborate women's longevity study
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MET -- metabolic equivalent task -- 3 per week
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High intake of what 2 things is beneficial? - CORRECT ANSWER -fruits + vegs
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What percent of women will develop breast cancer if they have the BRAC1 or BRAC2 gene? - CORRECT
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ANSWER -80%
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What is the treatment if caught early stage? - CORRECT ANSWER -Lumpectomy -- breast
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conserving- -- followed by XRT
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ER + disease use hormone therapy = SERMS + AI's - CORRECT ANSWER -SERMs (selective
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estrogen receptor modulators) - tamoxifen, raloxifene, fluvestrant) -- decrease growth of
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estrogen-sensitive cells by binding to the estrogen receptor
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AI's(aromatase inhibitors)- anastrozole,exemestane, letrozole --blockestrogen receptors
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, high-risk post-meno women had 50% reduced risk of developing cancer when using this (breast
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cancer prevention trial) - CORRECT ANSWER -tamoxifen
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NCI study of Tamoxifen vs raloxifene found what - CORRECT ANSWER -
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both effective in reducing the risk among high risk disease
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what monoclonal antibody is used for breast cancers that overproduce HER2 -
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CORRECT ANSWER -trastuzumab
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AI's but not SERMS are associated with what SE? - CORRECT ANSWER -bone loss ---
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> Ca + Vit D
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how to ERD's work? (Estrogen-receptor down-regulators) - CORRECT ANSWER -
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block effects of estrogen In breast tissue
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how to LHRHs work? (Luteinizing hormone-relasing agents) - CORRECT ANSWER -
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Lupron, Depot, Zoladex v v




shut down ovaries so they do not produce estrogen
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incidence of mixed ER/PR cancers - CORRECT ANSWER -ER - PR - ===== 20% v v v v v v v v v v v v v




v ER + PR - ==== 10%
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ER - PR + ===== 5%
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HER 2 + breast cancer - CORRECT ANSWER -20% of cancers
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v fast growing + aggressive
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Monoclonal antibody -- herceptin v v v




Triple negative breast cancer - CORRECT ANSWER -15-20%
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