NURS 6032 Exam 1 2025/2026 Questions with
Correct Key Answers Well Detailed Exam Fall
Semester (Sore A Original)-Marquette
University
What is the main difference of how antiviral drugs work vs antibiotics?
antivirals kill the host cell
Which type of medication prescribed to a pregnant patient is more likely to have effects
on the fetus?
a. drugs that are highly polar
b. ionized drugs
c. lipid soluble drugs
d. protein-bound drugs
c
lipid soluble drugs pass the placenta more easily
,A 5 y.o child present to your primary care clinic and has gray teeth. When taking a
medication hx, you will ask about previous use of which group of antibiotics?
a. PCN
b. cephalosporins
c. sulfonamides
d. tetracyclines
d
You are reviewing an older patient's chart during a routine clinic visit. Which patient
information is of most concern to you if they are on multiple protein bound
medications?
a. chronic constipation
b. low serum albumin
c. increased body fat
,d. low serum creatinine
b
A patient has a localized skin infection, which is most likely caused by a gram positive
cocci. Until the culture and sensitivity results are available, you plan to order a ____
spectrum ____ drug.
a. broad; systemic
b. broad; topical
c. narrow; systemic
d. narrow; topical
d
because this is a localized infection a topical agent is recommended
and unless the infection is very serious, a narrow spectrum antibiotic would be best
(choose one with good gram positive coverage bc that is what tends to grow on skin)
Your patient is taking drug A, a pro drug that is a substrate for the CYPA12 enzyme. You
start them on drug B, which is a strong inhibitor of CYPA12. What do you anticipate will
happen?
, a. there will be no impact on levels of either drug
b. the therapeutic efficacy of drug A will be significant reduced
c. the pt will be at risk for drug B toxicity
d. the pt will be at risk for drug A toxicity
b
since pro drugs need metabolism to become active if you inhibit the enzyme needed to
metabolize drug A you will have subtherapeutic levels of drug A
it would be the opposite if it were a normal drug (not a prodrug) strong inhibition of
CYPA12 would place pt at risk for drug A toxicity (bc less of it would be broken down
and excreted, so serum levels would be high)
pro-drugs
inactive drugs that rely on metabolism to become active
You determine that a patient requires a prescription for a narrow-spectrum antibiotic
to treat a gram positive cocci-related infection. What tx options would you consider?
select all.
Correct Key Answers Well Detailed Exam Fall
Semester (Sore A Original)-Marquette
University
What is the main difference of how antiviral drugs work vs antibiotics?
antivirals kill the host cell
Which type of medication prescribed to a pregnant patient is more likely to have effects
on the fetus?
a. drugs that are highly polar
b. ionized drugs
c. lipid soluble drugs
d. protein-bound drugs
c
lipid soluble drugs pass the placenta more easily
,A 5 y.o child present to your primary care clinic and has gray teeth. When taking a
medication hx, you will ask about previous use of which group of antibiotics?
a. PCN
b. cephalosporins
c. sulfonamides
d. tetracyclines
d
You are reviewing an older patient's chart during a routine clinic visit. Which patient
information is of most concern to you if they are on multiple protein bound
medications?
a. chronic constipation
b. low serum albumin
c. increased body fat
,d. low serum creatinine
b
A patient has a localized skin infection, which is most likely caused by a gram positive
cocci. Until the culture and sensitivity results are available, you plan to order a ____
spectrum ____ drug.
a. broad; systemic
b. broad; topical
c. narrow; systemic
d. narrow; topical
d
because this is a localized infection a topical agent is recommended
and unless the infection is very serious, a narrow spectrum antibiotic would be best
(choose one with good gram positive coverage bc that is what tends to grow on skin)
Your patient is taking drug A, a pro drug that is a substrate for the CYPA12 enzyme. You
start them on drug B, which is a strong inhibitor of CYPA12. What do you anticipate will
happen?
, a. there will be no impact on levels of either drug
b. the therapeutic efficacy of drug A will be significant reduced
c. the pt will be at risk for drug B toxicity
d. the pt will be at risk for drug A toxicity
b
since pro drugs need metabolism to become active if you inhibit the enzyme needed to
metabolize drug A you will have subtherapeutic levels of drug A
it would be the opposite if it were a normal drug (not a prodrug) strong inhibition of
CYPA12 would place pt at risk for drug A toxicity (bc less of it would be broken down
and excreted, so serum levels would be high)
pro-drugs
inactive drugs that rely on metabolism to become active
You determine that a patient requires a prescription for a narrow-spectrum antibiotic
to treat a gram positive cocci-related infection. What tx options would you consider?
select all.
