ANSWERS GRADED A+
✔✔Aminoglycoside drugs - ✔✔Gentamycin, tobramycin
✔✔Aminoglycoside uses - ✔✔Atypical coverage, resistant infections, tobramycin for CF
only
✔✔Aminoglycoside AEs - ✔✔Ototoxicity (irreversible), nephrotoxicity (reversible)
✔✔Aminoglycoside monitoring - ✔✔Renal dose adjust, hearing test, drug level
monitoring
✔✔Antifungals (azoles) - ✔✔Fluconazole, itraconazole
✔✔Itraconazole interactions - ✔✔Acid suppressive therapies
✔✔Fluconazole dose adjust - ✔✔Renal
✔✔Antifungal AEs - ✔✔GI, QTc prolongation (fluconazole)
✔✔Antifungal drug interactions - ✔✔QT prolongation meds, warfarin
✔✔Anti-infectives not for pregnant - ✔✔Tetracyclines, TMP-SMZ
✔✔TMP-SMZ coverage - ✔✔G+, G-, MRSA, Protozoa (toxoplasma gondii), fungus
(pneumocystis jirovecii), poor anaerobic activity
✔✔TMP-SMZ AEs - ✔✔Sulfa allergy, photosensitivity, hematologic (anemia,
leukopenia, thrombocytopenia)
✔✔TMP-SMZ on renal function - ✔✔Dose adjust in renal impairment, false elevation in
serum Cr
✔✔TMP-SMZ drug interactions - ✔✔Warfarin
✔✔Gram + only coverage - ✔✔Clindamycin, linezolid, vancomycin, daptomycin
✔✔Gram - only - ✔✔Monobactams (aztreonam), penicillin VK
✔✔Gram +/- - ✔✔PCN (aminopcn, ext. spectrum), carbapenams, aminoglycosides,
TMP-SMZ, fluoroquinolones, fosfomycin
✔✔Head growth in first year of life - ✔✔Total 12cm
, ✔✔Head growth 0-3mo - ✔✔6cm
✔✔Head growth 4-6mo - ✔✔3cm
✔✔Head growth 6-12mo - ✔✔3cm
✔✔Head growth 2-7yo - ✔✔0.5cm/yr
✔✔Head growth 8-12yo - ✔✔0.3cm/yr
✔✔Tumor grading: T0 - ✔✔No evidence of primary tumor
✔✔Tumor grading: T1 - ✔✔2 cm or less in greatest dimension
✔✔Tumor grading: T2 - ✔✔>2-5cm
✔✔Tumor grading: T3 - ✔✔>5cm
✔✔Chvostek sign - ✔✔Hypocalcemia, spasm when tap facial nerve
✔✔Trousseau sign - ✔✔Hypocalcemia, spasm when compress brachial artery w/ BP
cuff
✔✔Myocardial ischemia EKG changes - ✔✔Inverted T wave, T wave depression
✔✔Myocardial injury EKG changes, - ✔✔ST segment elevation, tall peaked t wave
✔✔Myocardial infarction EKG changes - ✔✔Q wave
✔✔1st gen antihistamines - ✔✔Diphenhydramine, chlorpheniramine
✔✔2nd gen antihistamines - ✔✔Loratadine, desloratadine, cetirizine, fexofenadine,
levocetirazine
✔✔Ishihara chart - ✔✔Test for color blindness
✔✔Scarlet fever presentation - ✔✔Sandpaper-like rash, exudative pharyngitis, localized
anterior cervical lymphadenopathy, rash 2 days after pharyngitis then peels later
✔✔Roseola (HHV-6) presentation - ✔✔Rash lasts hours to 3 days, follows 3-7 day high
fever, sometimes febrile seizures, tx supportive