WALDEN UNIVERSITY NURS 6630 MIDTERM
EXAMPREP 2026 COMPLETE EXAM SET WITH
REAL QUESTIONS AND CORRECT ANSWERS
GRADED A+
◉ Mirtazapine's inhibition of Histamine H1 receptors causes:.
Answer: sedation (could be desirable side effect for depressed
individuals with insomnia)
◉ For depressed individuals with anorexia, increased appetite and
weight gain, are possibly beneficial side effects of this Atypical
Antidepressant:. Answer: mirtazapine
◉ As Serotonin Antagonists, these two Atypical Antidepressants
block 5-HT2A receptors so that more Serotonin is available to bind
to 5-HT1A receptors which are more strongly linked to depression:.
Answer: trazodone and nefazodone
◉ In addition to inhibition of 5-HT2A receptors, these two Atypical
Antidepressants increase levels of Serotonin in the synaptic cleft
through weak inhibition of Serotonin reuptake transporters:.
Answer: trazodone and nefazodone
,◉ First line therapy for MDD due to milder side effect profiles.
Answer: SSRIs
◉ Six Common SSRIs. Answer: citalopram, escitalopram, fluoxetine,
fluvoxamine, sertraline, paroxetine
◉ Onset of therapeutic benefit from SSRIs. Answer: 4-6 weeks
◉ In addition to MDD, SSRIs also treat. Answer: Chronic Anxiety,
PTSD, OCD, and eating disorders (bulimia)
◉ Five Common side effects of SSRIs include. Answer: Anxiety,
insomnia, GI distress, sexual dysfunction (ED), SIADH
◉ Severe side effect of SSRIs in children/adolescents under age 25
years old. Answer: suicidal ideation
◉ Life threatening adverse effect of SSRIs, especially when used in
combination with other serotonergic drugs (SNRIs, TCAs, MAOIs,
etc.). Answer: Serotonin Syndrome
◉ Excess accumulation of serotonin resulting in overstimulation of
the nervous system. Answer: Serotonin Syndrome
, ◉ Seven symptoms of Serotonin Syndrome. Answer: Flushing,
hyperthermia, agitation, muscle rigidity, seizure, coma,
HYPERreflexia
◉ The treatment for serotonin syndrome. Answer: Cyproheptadine
(5-HT2 receptor antagonist)
◉ Cyproheptadine treats serotonin syndrome by. Answer: blocking
5-HT2 receptors (serotonin antagonist)
◉ When SSRIs or SNRIs are stopped abruptly, common symptoms of
withdrawal include. Answer: Irritability, headaches, and insomnia
◉ Medicine specific side effect of citalopram. Answer: Prolonged QT
interval (normal=0.4.-0.44 seconds)
◉ This SSRI is pregnancy category D due to associations with
congenital heart defects. Answer: Paroxetine
◉ All SSRIs but paroxetine (D) are pregnancy category. Answer: C
◉ Three SSRIs that are inhibitors of Cytochrome P450 enzymes.
Answer: fluoxetine, fluvoxamine, and paroxetine
EXAMPREP 2026 COMPLETE EXAM SET WITH
REAL QUESTIONS AND CORRECT ANSWERS
GRADED A+
◉ Mirtazapine's inhibition of Histamine H1 receptors causes:.
Answer: sedation (could be desirable side effect for depressed
individuals with insomnia)
◉ For depressed individuals with anorexia, increased appetite and
weight gain, are possibly beneficial side effects of this Atypical
Antidepressant:. Answer: mirtazapine
◉ As Serotonin Antagonists, these two Atypical Antidepressants
block 5-HT2A receptors so that more Serotonin is available to bind
to 5-HT1A receptors which are more strongly linked to depression:.
Answer: trazodone and nefazodone
◉ In addition to inhibition of 5-HT2A receptors, these two Atypical
Antidepressants increase levels of Serotonin in the synaptic cleft
through weak inhibition of Serotonin reuptake transporters:.
Answer: trazodone and nefazodone
,◉ First line therapy for MDD due to milder side effect profiles.
Answer: SSRIs
◉ Six Common SSRIs. Answer: citalopram, escitalopram, fluoxetine,
fluvoxamine, sertraline, paroxetine
◉ Onset of therapeutic benefit from SSRIs. Answer: 4-6 weeks
◉ In addition to MDD, SSRIs also treat. Answer: Chronic Anxiety,
PTSD, OCD, and eating disorders (bulimia)
◉ Five Common side effects of SSRIs include. Answer: Anxiety,
insomnia, GI distress, sexual dysfunction (ED), SIADH
◉ Severe side effect of SSRIs in children/adolescents under age 25
years old. Answer: suicidal ideation
◉ Life threatening adverse effect of SSRIs, especially when used in
combination with other serotonergic drugs (SNRIs, TCAs, MAOIs,
etc.). Answer: Serotonin Syndrome
◉ Excess accumulation of serotonin resulting in overstimulation of
the nervous system. Answer: Serotonin Syndrome
, ◉ Seven symptoms of Serotonin Syndrome. Answer: Flushing,
hyperthermia, agitation, muscle rigidity, seizure, coma,
HYPERreflexia
◉ The treatment for serotonin syndrome. Answer: Cyproheptadine
(5-HT2 receptor antagonist)
◉ Cyproheptadine treats serotonin syndrome by. Answer: blocking
5-HT2 receptors (serotonin antagonist)
◉ When SSRIs or SNRIs are stopped abruptly, common symptoms of
withdrawal include. Answer: Irritability, headaches, and insomnia
◉ Medicine specific side effect of citalopram. Answer: Prolonged QT
interval (normal=0.4.-0.44 seconds)
◉ This SSRI is pregnancy category D due to associations with
congenital heart defects. Answer: Paroxetine
◉ All SSRIs but paroxetine (D) are pregnancy category. Answer: C
◉ Three SSRIs that are inhibitors of Cytochrome P450 enzymes.
Answer: fluoxetine, fluvoxamine, and paroxetine
