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NURSING 6550 Week 8 iHUMAN Case Study: Comprehensive for Major Depressive Disorder | PMHNP Clinical Assessment and Management

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NURSING 6550 Week 8 iHUMAN Case Study: Comprehensive for Major Depressive Disorder | PMHNP Clinical Assessment and Management

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January 6, 2026
Number of pages
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Written in
2025/2026
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NURSING 6550 Week 8 iHUMAN Case Study:
Comprehensive for Major Depressive Disorder | PMHNP
Clinical Assessment and Management




In-depth NURSING 6550 Week 8 iHUMAN case study featuring a complete for a patient
with major depressive disorder. Includes DSM-5 diagnosis, mental status exam, screening
tools, evidence-based pharmacologic and non-pharmacologic treatment, safety planning, and
expert clinical reasoning for PMHNP students.




• NURSING 6550 Week 8 iHUMAN
• PMHNP iHUMAN case study
• Major depressive disorder
• Psychiatric example
• DSM-5 PMHNP case study




Patient Information
Name: [iHUMAN Virtual Patient]
Age: 38 years
Sex: Female
Ethnicity: Caucasian
Source of History: Patient (reliable)
Setting: Outpatient Mental Health Clinic




Chief Complaint (CC):
“I feel sad all the time and can’t enjoy anything anymore.”

, S – Subjective
History of Present Illness (HPI):

The patient is a 38-year-old female presenting with persistent depressed mood for the past 3
months. She reports feeling sad, hopeless, and emotionally numb most days, with loss of
interest in activities she previously enjoyed. Symptoms began gradually following increased work
stress and have progressively worsened.

She endorses fatigue, difficulty concentrating, insomnia, and feelings of worthlessness.
Appetite has decreased, resulting in an unintentional 5-lb weight loss over two months. She denies
manic symptoms, hallucinations, delusions, or paranoia.

She admits to passive thoughts of death but denies active suicidal ideation, intent, or plan. No
prior psychiatric hospitalizations.



Associated Symptoms:

• Low energy
• Anhedonia
• Poor concentration
• Sleep disturbance

Denies:

• Hallucinations
• Mania or hypomania
• Substance abuse
• Active suicidal ideation



Past Psychiatric History:

• No prior formal psychiatric diagnosis
• No prior therapy or psychiatric medications



Past Medical History (PMH):

• Hypothyroidism (controlled)



Current Medications:

• Levothyroxine 75 mcg PO daily
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