BCOP - Breast Exam Questions with Correct Answers| Latest Update Guaranteed Success
Risk factors for breast cancer Family history, over age 50, menses before 12, no children, 1st
pregnancy after 30, menopause after 55
A HER2 score of 2+ by IHC is only considered HER2+ if _______ FISH testing is +
This tool is used to determine relative risk of developing breast cancer Gail Model
Benefits (3) of raloxifene over tamoxifen less endometrial hyperplasia, incidence of VTE, and
cataracts
Benefit of tamoxifen over raloxifene Superior in reducing invasive breast cancer
Adverse drug reactions for exemestane (4) Arthritis, hot flashes, insomnia, joint/muscle pain
Adverse drug reactions for anastrazole (5) arthralgias, carpal tunnel syndrome, dry eyes,
vaginal dysfunction (dryness, pruritus, prolapse), hypertension
Aromatase inhibitors Anastrozole, exemestane, letrozole
Selective Estrogen Receptor Modulators (SERMs) Tamoxifen, Raloxifene
Surgical breast cancer risk reduction options bilateral total mastectomy +/- reconstruction,
BSO
Consider endocrine therapy when Gail risk is >/= _______ 1.7%
, Hormone therapy options for breast cancer risk reduction in premenopausal women
tamoxifen x 5 years, consider another 5 if still premenopausal
Hormone therapy options for breast cancer risk reduction in postmenopausal women
tamoxifen, anastrozole, raloxifene, exemestastane x 5 year s
Relative contraindication for aromatase inhibitors osteoporosis, bone loss or low bone
density
Precaution to consider before starting tamoxifen history of VTE, PE, or TIA
Oncotype DX is used to ________ predict the likelihood of distant disease recurrence and
benefit from adjuvant chemotherapy in patients with ER (+), HER2 (-), and node-
negative/positive (up to 3 nodes)
Local management options for DCIS 1) Breast-conserving surgery (BCS) aka lumpectomy +/-
radiation
2) Total mastectomy +/- reconstruction
After BCS, radiation reduces recurrence rates of DCIS by about _____% 50%
Endocrine therapy for DCIS Premenopausal: Tamoxifen
Postmenopausal: Anastrozole or tamoxifen
Following BCS +/- radiation in patients with ER(+) DCIS, what can we give to decrease risk of
ipsilateral recurrence? Endocrine therapy for 5 years
In patients over 50yo, what does an oncotype dx score of <25 indicate? no benefit from
adjuvant chemo, endocrine therapy alone is recommended
Risk factors for breast cancer Family history, over age 50, menses before 12, no children, 1st
pregnancy after 30, menopause after 55
A HER2 score of 2+ by IHC is only considered HER2+ if _______ FISH testing is +
This tool is used to determine relative risk of developing breast cancer Gail Model
Benefits (3) of raloxifene over tamoxifen less endometrial hyperplasia, incidence of VTE, and
cataracts
Benefit of tamoxifen over raloxifene Superior in reducing invasive breast cancer
Adverse drug reactions for exemestane (4) Arthritis, hot flashes, insomnia, joint/muscle pain
Adverse drug reactions for anastrazole (5) arthralgias, carpal tunnel syndrome, dry eyes,
vaginal dysfunction (dryness, pruritus, prolapse), hypertension
Aromatase inhibitors Anastrozole, exemestane, letrozole
Selective Estrogen Receptor Modulators (SERMs) Tamoxifen, Raloxifene
Surgical breast cancer risk reduction options bilateral total mastectomy +/- reconstruction,
BSO
Consider endocrine therapy when Gail risk is >/= _______ 1.7%
, Hormone therapy options for breast cancer risk reduction in premenopausal women
tamoxifen x 5 years, consider another 5 if still premenopausal
Hormone therapy options for breast cancer risk reduction in postmenopausal women
tamoxifen, anastrozole, raloxifene, exemestastane x 5 year s
Relative contraindication for aromatase inhibitors osteoporosis, bone loss or low bone
density
Precaution to consider before starting tamoxifen history of VTE, PE, or TIA
Oncotype DX is used to ________ predict the likelihood of distant disease recurrence and
benefit from adjuvant chemotherapy in patients with ER (+), HER2 (-), and node-
negative/positive (up to 3 nodes)
Local management options for DCIS 1) Breast-conserving surgery (BCS) aka lumpectomy +/-
radiation
2) Total mastectomy +/- reconstruction
After BCS, radiation reduces recurrence rates of DCIS by about _____% 50%
Endocrine therapy for DCIS Premenopausal: Tamoxifen
Postmenopausal: Anastrozole or tamoxifen
Following BCS +/- radiation in patients with ER(+) DCIS, what can we give to decrease risk of
ipsilateral recurrence? Endocrine therapy for 5 years
In patients over 50yo, what does an oncotype dx score of <25 indicate? no benefit from
adjuvant chemo, endocrine therapy alone is recommended
