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Chromosomes and Meiosis Grade 12 Life Sciences

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Chromosomes and Meiosis:
Chromosomes:
 Long, thread-like structures that form part of the chromatin network in nuclei cells.
 Made up of stand of DNA wound around histones (proteins)
 Can only be seen as individual threads when cell is dividing.

In somatic (body) cells of diploid organisms:
 No. of chromosomes in each cell is the same
 Chromosomes are made up of two sets:
1. One chromosomes of each pair come from the mother (maternal
chromosome)
2. One comes from the father (paternal chromosome)
∴ called diploid cells (di-two) or 2n for short 2n = 46
 For each paternal chromosome there is a matching maternal chromosome
forming a homologous pair.
>> forming a pair (chromosomes) = same size, shape, and genes in same
place, but alleles for each trait may not be the same.
 DNA of each, replicates to form 2 identical threads or chromatids joined by a
centromere (takes place in interphase of cell cycle)
>> threads shorten and thicken as cell divides = visibility.
 Replication of DNA is very important to ensure cell divides, each daughter cell
receives full complement of all genetic material.

What is meant by a chromosome number?
 Each species has a specific number of chromosomes in its somatic cell.
(some organisms have identical chromosome nos. which are not related)
 Similarities in DNA of chromosomes shows relationships, not their number.

Meiosis:
Meiosis is cell division that takes place in reproductive organs of both plants and
animal sot produce gametes (sex cells) in animals and spores in plants.
 No. of chromosomes is reduced from two sets (2n) in parent cell to one set (n)
in each of daughter cells formed (halved)
 Gametes or spores are formed (haploid) – only have one set of
chromosomes. i.e. one chromosome from each homologous pair.
>> In sexual reproduction, a male haploid gamete fuses with a female haploid
gamete during fertilisation to form a diploid zygote.



Where does meiosis take place?

, Animals: (testis and ovaries)
 Formation of sperm cells in testis  spermatogenesis
 Formation of egg cells/ova in ovaries  oogenesis
Plants: (formation of spores in sporangia)
 Microsporangia are pollen sacs in male anthers
 Megasporangia are ovules in female ovaries.

The process of meiosis:
In meiosis, replication is followed by two divisions:
>> Meiosis 1: reduction division which results in two cells being formed each with
half the no. of chromosomes of parent cell. i.e. haploid (n) number.
>> Meiosis 2: copying division which involves two haploid cells formed, each
dividing again by mitosis to form 4 haploid cells.

Meiosis 1 – a reduction division:
Early prophase 1
 As in mitosis, the chromosomes become short and fat and are visible as two
chromatids joined by a centromere.




Late prophase 1
 The chromosomes of the homologous pairs lie along side one another, forming a
bivalent.
 The centrioles move to opposite poles.
 A spindle, made up of protein threads, develops across the cell from the two
centrioles.
 It is at this stage that crossing over, takes place.


Metaphase 1
 The bivalents (not the chromosomes) move to the middle of the cell and line up
on the equator.
 The centromeres become attached to the spindle threads.
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