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HESI PN Comprehensive Exam Study Guide | Complete Practice Questions & Answers | Nursing Exam Prep

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Prepare for the HESI PN Comprehensive Exam with this detailed study guide. This resource includes practice questions and verified answers designed to cover all critical topics for the Practical Nurse exam, including medical-surgical nursing, pharmacology, pediatric nursing, and maternal health. Ideal for nursing students and aspiring Practical Nurses, this guide ensures you’re fully equipped to succeed on your HESI PN exam and secure your certification.

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January 4, 2026
Number of pages
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Written in
2025/2026
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HESI PN Comprehensive
Exam (NEW 2026/ 2027 Update) Questions
& Answers 100% Correct (Verified
Solutions) [Grade A] - Hondros




Which information should the practical nurse (PN) provide to an unlicensed assistive

personnel (UAP) who is newly assigned to the unit?


A. Keep head-of-bed elevated 45 degrees for clients with an infusing enteral pump.
B. Determine if pain subsides 20 minutes after a client receives an injection.

C. Report signs of infection in urine that collects in a bedside drainage unit.
D. Observe how clients are using an incentive spirometer after surgery. - correct

answer A. Keep head-of-bed elevated 45 degrees for clients with an infusing enteral

pump.


Rationale: Information about the basic care clients such as positioning (A) should be
specific to a common intervention or treatment and should focus on task within the

scope of the UAP's assignment


A woman who is 32-weeks gestation arrives at the prenatal clinic and reports painless
contractions and mucoid vaginal discharge. The fetal heart rate is 150 beats/minutes.

What action should the practical nurse (PN) implement first?

, HESI PN Comprehensive
Exam (NEW 2026/ 2027 Update) Questions
& Answers 100% Correct (Verified
Solutions) [Grade A] - Hondros


A. Place in the left lateral recumbent position.

B. Ask about recent sexual intercourse.
C. Encourage an increase in oral fluid intake.

D. Determine when the contractions began. - correct answer A. Place in the left lateral
recumbent position.


Rationale: Preterm labors symptoms include contractions and mucoid vaginal

discharge so the PN should place the client in the left lateral position
A newborn with apnea is being discharged from the hospital with home monitoring.

What information concerning the infant's care should the practical nurse review with

the parents?


A. Cardiopulmonary resuscitation (CPR).
B. Administration of intravenous antibiotics.

C. Reassurance that the infant cannot be electrocuted during monitoring.
D. Advise that the infant not be left with caretakers, such as babysitters. - correct

answer A. Cardiopulmonary resuscitation (CPR).


Rationale: Apnea of infancy (AOI) engenders great anxiety in parents, and the
initiation of home monitoring presents additional emotional stress. When home

, HESI PN Comprehensive
Exam (NEW 2026/ 2027 Update) Questions
& Answers 100% Correct (Verified
Solutions) [Grade A] - Hondros


monitoring is required the parents should receive instructions that include

cardiopulmonary resuscitation(A). (B) does not indicate Apnea


Which protocol regarding standard policies about prescriptions should the practical
nurse (PN) question?


A. All drug prescriptions should have the date, time, and prescriber's signature.

B.Verbal orders are accepted from prescribers and should include signatures.
C. Prescribers may write specific times at which the medications are to be given.

D. Preoperative prescriptions should be resumed after a client returns from surgery -

correct answer D. Preoperative prescriptions should be resumed after a client returns
from surgery.


Rationale: A standard policy about preoperative medications that preoperative

prescriptions are automatically canceled for surgery and should be rewritten, if
indicated , in the postoperatively so the (PN) should question (D). (A,B,C) are correct

statements.


When reviewing the safety precautions regarding newborns, what information should
the practical nurse communicate to the parents?

, HESI PN Comprehensive
Exam (NEW 2026/ 2027 Update) Questions
& Answers 100% Correct (Verified
Solutions) [Grade A] - Hondros



A. Position the infant to sleep on the baby's back.
B. Use a crib with slats no more than 4 inches apart.

C. Propping a bottle can be done when the infant gets older.
D. Place the infant a front-facing car seat in the automobile. - correct answer A.

Position the infant to sleep on the baby's back.


Rationale: The incident of sudden infant death syndrome (SIDS) decline when infants
are positioned on their backs (A), instead of prone for sleeping. Crib slats (B) 2.375

inches apart to prevent the baby from slipping. (C) Never prop a babies bottle.

(D)Infant who weighs less than 30lbs should be placed in a rear facing car seat.
Which action should the practical nurse perform first for a child who is injured on the

school grounds and has an obvious mis-alignment of the lower forearm?


A. Remove the child's finger rings.
B. Assess and document the child's level of pain.

C. Evaluate the child's range of motion.
D. Place arm in a sling at level of the child's heart. - correct answer A. Remove the

child's finger rings.
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