BIOL331 / BIOL 331 Module 3
(Latest Update )
Pathophysiology | Questions &
Answers | Grade A | 100% Correct -
Portage Learning
Mechanisms of Self-defense: Immunity & Dysfunctions
Question:
platelets role in inflammation
Answer:
They release inflammatory mediators to increase vascular permeability and
alter various endothelial cell properties(adhesive, chemotactic and
proteolytic).
Question:
Neutrophils role in inflammation:
Answer:
Primary phagocytes that arrive early to injury site.
,Question:
Lifespan of neutrophils:
What does the short lifespan require?
Answer:
10 hours.
Need to be replaced constantly.
Question:
Elevated white blood cell count is referred to as:
Answer:
leukocytosis
Question:
If the demand is increased for neutrophils, what may be produced?
Answer:
Bands, which are an immature neutrophil.
,Question:
Monocytes as part of inflammation
Answer:
Produce various strong vasoactive mediators, inflammatory cytokines,
platelet activating factor and growth factors for tissue regeneration.
Key role in chronic inflammation:
-Surround and wall off foreign materials that cannot be digested.
Question:
Signs and symptoms of inflammation are caused by:
Answer:
chemical mediators
Question:
Chemical mediators can originate from:
Answer:
Plasma or cells
, Question:
Plasma mediators and how they are activated:
Cell-derived mediators activation:
Answer:
Plasma mediators: Coagulation factors and complement proteins-activated by
proteolytic processes.
Cell-derived: In response to microbes or damaged tissues.
Question:
Inflammatory mediators are classified by:
What are the classifications?
Answer:
Function
1. Vasoactive and smooth muscle contracting properties
-histamine, arachidonic acid metabolites (leukotrienes and prostaglandins)
2. Plasma proteases that activate members of the complement system,
coagulation factors of the clotting cascade and vasoactive peptides of the
kinin system.
3. Chemotactic factors (chemokines)
4. Reactive molecules and cytokines from leukocytes.
(Latest Update )
Pathophysiology | Questions &
Answers | Grade A | 100% Correct -
Portage Learning
Mechanisms of Self-defense: Immunity & Dysfunctions
Question:
platelets role in inflammation
Answer:
They release inflammatory mediators to increase vascular permeability and
alter various endothelial cell properties(adhesive, chemotactic and
proteolytic).
Question:
Neutrophils role in inflammation:
Answer:
Primary phagocytes that arrive early to injury site.
,Question:
Lifespan of neutrophils:
What does the short lifespan require?
Answer:
10 hours.
Need to be replaced constantly.
Question:
Elevated white blood cell count is referred to as:
Answer:
leukocytosis
Question:
If the demand is increased for neutrophils, what may be produced?
Answer:
Bands, which are an immature neutrophil.
,Question:
Monocytes as part of inflammation
Answer:
Produce various strong vasoactive mediators, inflammatory cytokines,
platelet activating factor and growth factors for tissue regeneration.
Key role in chronic inflammation:
-Surround and wall off foreign materials that cannot be digested.
Question:
Signs and symptoms of inflammation are caused by:
Answer:
chemical mediators
Question:
Chemical mediators can originate from:
Answer:
Plasma or cells
, Question:
Plasma mediators and how they are activated:
Cell-derived mediators activation:
Answer:
Plasma mediators: Coagulation factors and complement proteins-activated by
proteolytic processes.
Cell-derived: In response to microbes or damaged tissues.
Question:
Inflammatory mediators are classified by:
What are the classifications?
Answer:
Function
1. Vasoactive and smooth muscle contracting properties
-histamine, arachidonic acid metabolites (leukotrienes and prostaglandins)
2. Plasma proteases that activate members of the complement system,
coagulation factors of the clotting cascade and vasoactive peptides of the
kinin system.
3. Chemotactic factors (chemokines)
4. Reactive molecules and cytokines from leukocytes.
