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Pathophysiology HESI Exam 2025–2026 | Verified Questions, Answers, and Study Guide

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This resource provides a comprehensive Pathophysiology HESI study guide, featuring verified questions and correct answers. It covers disease mechanisms, clinical manifestations, pharmacologic interventions, and patient care considerations, designed for nursing students preparing for HESI exams. This guide supports exam preparation, self-assessment, and mastery of pathophysiology concepts, enabling students to achieve top scores and enhanced clinical reasoning.

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HESI RN ADVANCED PATHOPHYSIOLOGY EXAM
HESI
BANK.pdf
RN ADVANCED PATHOPHYSIOLOGY EXAM
HESI
BANK.pdf
RN ADVANCED PATHOPHYSIOLOGY EXAM BANK.pdf




HESI RN ADVANCED PATHOPHYSIOLOGY
2024/2025 ACTUAL EXAM 160 QUESTIONS
AND CORRECT ANSWERS WITH
RATIONALES



a. positive feedback

An initial disturbance in a system sets off a chain of events that does not favor stability and often
abruptly displaces a system from its steady state: what is that?

a. Positive Feedback

b. Negative Feedback

c. Disease

d. Homeostasis




b. gums

What organ shrinks with age?

a. Prostate

b. Gums

c. Heart

d. All of the above




d. there is less thirst perception in the elderly

Which of the following is true?




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,HESI RN ADVANCED PATHOPHYSIOLOGY EXAM
HESI
BANK.pdf
RN ADVANCED PATHOPHYSIOLOGY EXAM
HESI
BANK.pdf
RN ADVANCED PATHOPHYSIOLOGY EXAM BANK.pdf




a. An infant will have a slower heart rate than an adult

b. The elderly have better temperature sensations

c. There are more sweat glands in an elderly person

d. There is less thirst perception in the elderly




c. Women have a lower hemoglobin than men

Which of the following is true?

a. Women snore more than men

b. Men have higher calcium levels

c. Women have a lower hemoglobin than men

d. Men have a lower creatinine level than women




b. Acclimatization

An increase in normal adaptive response to the decreased availability of oxygen at high altitude is
termed which?

a. Circadian

b. Acclimatization

c. Population

d. Diurnal




d. Iatrogenic

What does it mean when the cause of the disease is unwanted medical treatment?

a. Idiopathic




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,HESI RN ADVANCED PATHOPHYSIOLOGY EXAM
HESI
BANK.pdf
RN ADVANCED PATHOPHYSIOLOGY EXAM
HESI
BANK.pdf
RN ADVANCED PATHOPHYSIOLOGY EXAM BANK.pdf




b. Ecogenetic

c. Genotypical

d. Iatrogenic




d. Neonatal

Which term is used for the first two months of life?

a. Infancy

b. Childhood

c. Prenatal

d. Neonatal




d. Sign

Which is an objectively identifiable aberration of the disease?

a. Symptom

b. Syndrome

c. Stage

d. Sign




c. They include epinephrine and norepinephrine

Which of the following is true regarding catecholamines?

a. They are from the parasympathetic nervous system

b. They cross the blood brain barrier

c. They include epinephrine and norepinephrine




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, HESI RN ADVANCED PATHOPHYSIOLOGY EXAM
HESI
BANK.pdf
RN ADVANCED PATHOPHYSIOLOGY EXAM
HESI
BANK.pdf
RN ADVANCED PATHOPHYSIOLOGY EXAM BANK.pdf




d. They cause of decrease in heart rate




b. Endorphins increase with stress, resulting in a decrease in pain perception

Which of the following is a true statement?

a. Antidiuretic hormone is not important for blood volume regulation

b. Endorphins increase with stress, resulting in a decrease in pain perception

c. Epinephrine and cortisol act very differently

d. Cortisol negates epinephrine's activity




d. They cross by diffusion

By what mechanism do lipid molecules cross cell membranes?

a. They use channel proteins as a membrane transport system

b. They are transported across the plasma membrane by endocytosis and exocytosis

c. They use voltage-gated ion channels

d. They cross by diffusion




a. Protein synthesis

Which of the following metabolic processes is a component of anabolic metabolism?

a. Protein synthesis

b. Glycolysis

c. Citric acid cycle

d. Oxidative phosphorylation




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