WGU D027 PRACTICE TEST 1 QUESTIONS
WITH CORRECT ANSWERS 2025/2026
1. A Tpatient Thas Tendured Tseveral Tdosage Tadjustments Tof This Ttricyclic
Tantidepressant, Tso Tthe Tprovider Trecommends Tgenetic Ttesting. TWhich Tstatement
Tcorrectly Tdescribes Tthe Trationale Tfor Tgenetic Ttesting?
a. The TCYP2D6 Tgene Tinfluences Tmetabolism Tof Ttricyclic Tantidepressants Tand
Tcertain Tother Tdrugs.
b. The THER2 Tgene Tis Ta Ttumor Tmarker Tthat Timpacts Tmetabolism Tof
Ttricyclic Tantidepressants.
c. The TBRCA2 Tgene Tinfluences Tmetabolism Tof Tcertain Tdrugs Tand Tincreases Tthe
Trisk Tfor Tbreast Tcancer.
d. The Tx Tlinked TOPN1MW Tgene Tfor Tmale Tcolor Tblindness Talso Tslows
Tmetabolism Tof Tcertain T- TCORRECT TANSWER T-a. TThe TCYP2D6 Tgene
Tinfluences Tmetabolism Tof
tricyclic Tantidepressants Tand Tcertain Tother Tdrugs.
2. HER2 Tis Ta Tgene Toften Timplicated Twith Tcancer, Tas Tis TBRCA2. TOPN1MW Tis Tthe
Tgene Tthat Tcodes Tfor Tcolor Tblindness Tin Tmen. TMetabolism Tof T25% Tof Tall
Tprescribed Tdrugs, Tincluding Ttricyclic Tantidepressants, Tbeta Tadrenergic Treceptor
Tblockers, Tand Tneuroleptics, Tis Tinfluenced Tby Tvariants Tin Ta Tcertain Tgene,
Trequiring Tgenetic Ttesting Tto Treduce Ttrial-and- Terror Tin Testimating Tappropriate
Tdrug-dosage Tlevels.
3. According Tto Tthe TCenters Tfor TDisease TControl Tand TPrevention, Tthe T10 Tmost Tcostly
Tchronic Tconditions Tinclude Tcardiovascular Tdiseases, Tobesity, Tasthma, Tdiabetes,
Tsmoking Tand
alcohol Trelated Tconditions, Tcancer, TAlzheimer's Tdisease, Tarthritis Tand Tstroke. TWhich
,Tare Tthe Ttop T4 Tin Tranking Tfrom Tmost Tcostly Tto Tleast Tcostly?
a. Cardiovascular Tdiseases, Tobesity, Tdiabetes, Tcancer
b. Cardiovascular Tdiseases, Tdiabetes, Tobesity, Tcancer
c. Cardiovascular Tdiseases, TSmoking-related Tconditions, TAlcohol-related
Tconditions, Tdiabetes
, d. Cardiovascular Tdiseases, TStroke, TObesity, TDiabetes T- TCORRECT TANSWER T-c.
Cardiovascular Tdiseases, TSmoking-related Tconditions, TAlcohol-related Tconditions,
Tdiabetes
4. A Tmother Tbrought Ther Tchild Tto Tthe Tdoctor Tfor Tgenetic Ttesting. TThe Thealth Tcare
Tprovider Twas Ttrying Tto Texplain Tthe Tgenetic Tresults Tof Tthe Tchild. TDuring This
Texplanation The Ttells Tthe Tmother Tthat Tthe Tchild Thas T2 TX Tchromosomes Tand Ta TY
Tchromosome Tin Teach Tcell. THe Tbegins Tto Texplain Tsome Tphysical Tappearances Tthe
Tmother Tmight Tnotice Ton Ther Tson. THe Texplains Tthat Tshe Tmight Tnotice Tthat The
Thas Tsparse Tbody Thair, Tlong Tlimbs Tand Tsmall Ttestes. TThe
health Tcare Tpractitioner Tis Texplaining Twhich Tsyndrome Tto Tthe Tmother.
a. Klinefelter Tsyndrome
b. Turners' Tsyndrome
c. Down Tsyndrome
d. Kawasaki's Tdisease T- TCORRECT TANSWER T-a. TKlinefelter Tsyndrome
5. Klinefelter Tsyndrome Tis Tan Tindividual Twith Tat Tleast T2 TX Tchromosomes Tand Ta TY
chromosome Tin Teach Tcell. TBecause Tof Tthe TY Tchromosome Tthese Tindividuals Thave Ta
Tmale Tappearance, Tbut Tthey Tare Tusually Tsterile Tand Tabout Thalf Tdevelop Tfemale-like
Tbreasts.
6. A Tpatient Treports Ta Tmaternal Tfamily Thistory Tof TLynch Tsyndrome. TWhich Tlaboratory
Tfinding Tmight Tindicate Ta Tneed Tfor Tfurther Ttesting Tfor Tthe Tpresence Tof TLynch
Tsyndrome Tin Tthis Tpatient?
a. Elevated T thyroid-stimulating Thormone
b. Low Tcortisol Tlevel
c. Positive Theme-occult Ttest
d. Sputum Tpositive Tfor TPseudomonas TAeruginosa T- TCORRECT TANSWER T-a.
TPositive Theme-occult Ttest
7. Positive Theme-occult Tbecause TLynch Tsyndrome Tis Ta Thereditary Tform Tof Tcolorectal
Tcancer Tand Tcolorectal Tbleeding Tcan Tbe Ta Tsign Tof Tcancer
WITH CORRECT ANSWERS 2025/2026
1. A Tpatient Thas Tendured Tseveral Tdosage Tadjustments Tof This Ttricyclic
Tantidepressant, Tso Tthe Tprovider Trecommends Tgenetic Ttesting. TWhich Tstatement
Tcorrectly Tdescribes Tthe Trationale Tfor Tgenetic Ttesting?
a. The TCYP2D6 Tgene Tinfluences Tmetabolism Tof Ttricyclic Tantidepressants Tand
Tcertain Tother Tdrugs.
b. The THER2 Tgene Tis Ta Ttumor Tmarker Tthat Timpacts Tmetabolism Tof
Ttricyclic Tantidepressants.
c. The TBRCA2 Tgene Tinfluences Tmetabolism Tof Tcertain Tdrugs Tand Tincreases Tthe
Trisk Tfor Tbreast Tcancer.
d. The Tx Tlinked TOPN1MW Tgene Tfor Tmale Tcolor Tblindness Talso Tslows
Tmetabolism Tof Tcertain T- TCORRECT TANSWER T-a. TThe TCYP2D6 Tgene
Tinfluences Tmetabolism Tof
tricyclic Tantidepressants Tand Tcertain Tother Tdrugs.
2. HER2 Tis Ta Tgene Toften Timplicated Twith Tcancer, Tas Tis TBRCA2. TOPN1MW Tis Tthe
Tgene Tthat Tcodes Tfor Tcolor Tblindness Tin Tmen. TMetabolism Tof T25% Tof Tall
Tprescribed Tdrugs, Tincluding Ttricyclic Tantidepressants, Tbeta Tadrenergic Treceptor
Tblockers, Tand Tneuroleptics, Tis Tinfluenced Tby Tvariants Tin Ta Tcertain Tgene,
Trequiring Tgenetic Ttesting Tto Treduce Ttrial-and- Terror Tin Testimating Tappropriate
Tdrug-dosage Tlevels.
3. According Tto Tthe TCenters Tfor TDisease TControl Tand TPrevention, Tthe T10 Tmost Tcostly
Tchronic Tconditions Tinclude Tcardiovascular Tdiseases, Tobesity, Tasthma, Tdiabetes,
Tsmoking Tand
alcohol Trelated Tconditions, Tcancer, TAlzheimer's Tdisease, Tarthritis Tand Tstroke. TWhich
,Tare Tthe Ttop T4 Tin Tranking Tfrom Tmost Tcostly Tto Tleast Tcostly?
a. Cardiovascular Tdiseases, Tobesity, Tdiabetes, Tcancer
b. Cardiovascular Tdiseases, Tdiabetes, Tobesity, Tcancer
c. Cardiovascular Tdiseases, TSmoking-related Tconditions, TAlcohol-related
Tconditions, Tdiabetes
, d. Cardiovascular Tdiseases, TStroke, TObesity, TDiabetes T- TCORRECT TANSWER T-c.
Cardiovascular Tdiseases, TSmoking-related Tconditions, TAlcohol-related Tconditions,
Tdiabetes
4. A Tmother Tbrought Ther Tchild Tto Tthe Tdoctor Tfor Tgenetic Ttesting. TThe Thealth Tcare
Tprovider Twas Ttrying Tto Texplain Tthe Tgenetic Tresults Tof Tthe Tchild. TDuring This
Texplanation The Ttells Tthe Tmother Tthat Tthe Tchild Thas T2 TX Tchromosomes Tand Ta TY
Tchromosome Tin Teach Tcell. THe Tbegins Tto Texplain Tsome Tphysical Tappearances Tthe
Tmother Tmight Tnotice Ton Ther Tson. THe Texplains Tthat Tshe Tmight Tnotice Tthat The
Thas Tsparse Tbody Thair, Tlong Tlimbs Tand Tsmall Ttestes. TThe
health Tcare Tpractitioner Tis Texplaining Twhich Tsyndrome Tto Tthe Tmother.
a. Klinefelter Tsyndrome
b. Turners' Tsyndrome
c. Down Tsyndrome
d. Kawasaki's Tdisease T- TCORRECT TANSWER T-a. TKlinefelter Tsyndrome
5. Klinefelter Tsyndrome Tis Tan Tindividual Twith Tat Tleast T2 TX Tchromosomes Tand Ta TY
chromosome Tin Teach Tcell. TBecause Tof Tthe TY Tchromosome Tthese Tindividuals Thave Ta
Tmale Tappearance, Tbut Tthey Tare Tusually Tsterile Tand Tabout Thalf Tdevelop Tfemale-like
Tbreasts.
6. A Tpatient Treports Ta Tmaternal Tfamily Thistory Tof TLynch Tsyndrome. TWhich Tlaboratory
Tfinding Tmight Tindicate Ta Tneed Tfor Tfurther Ttesting Tfor Tthe Tpresence Tof TLynch
Tsyndrome Tin Tthis Tpatient?
a. Elevated T thyroid-stimulating Thormone
b. Low Tcortisol Tlevel
c. Positive Theme-occult Ttest
d. Sputum Tpositive Tfor TPseudomonas TAeruginosa T- TCORRECT TANSWER T-a.
TPositive Theme-occult Ttest
7. Positive Theme-occult Tbecause TLynch Tsyndrome Tis Ta Thereditary Tform Tof Tcolorectal
Tcancer Tand Tcolorectal Tbleeding Tcan Tbe Ta Tsign Tof Tcancer