The University of York (UOY) • Biology
Examens, Klausuren oder Prüfungen zu Biology @ The University of York (UOY). Suchst du nach den besten Studienführern, Studiennotizen und Zusammenfassungen für Biology an der The University of York (UOY)? Wir haben viele Zusammenfassungen und Notizen deiner Schule oder Universität.
-
16
- 0
- 0
Kurse Biology @ The University of York (UOY)
Notizen für die Kurse von Biology der The University of York (UOY)
-
Biology BIOL1000 1
-
Molecular Genetics and Development BIO00052I 15
Aktuellste Notizen und Zusammenfassungen The University of York (UOY) • Biology
- To give an overview of genomic imprinting, when it is initiated and how imprinting disorders can arise
- Describe key events in X-inactivation including the role of the Xist non-coding RNA
- Book
- Notizen
- • 8 Seiten 's •
-
The University of York•Molecular Genetics and Development
-
Principles of Development • Lewis Wolpert, Jim Smith• ISBN 9780198800569
Vorschau 2 aus 8 Seiten
- To give an overview of genomic imprinting, when it is initiated and how imprinting disorders can arise
- Describe key events in X-inactivation including the role of the Xist non-coding RNA
- Discuss the evidence for the nodal morphogen acting during mesoderm induction.
- Discuss the concept of the vertebrate dorsal organiser.
- Discuss the evidence that the brachyury transcription factor is a conserved regulator of germ layer specification.
- Draw conclusions regarding the molecular pathways regulating development of Urbilateria.
- Book
- Notizen
- • 8 Seiten 's •
-
The University of York•Molecular Genetics and Development
-
Principles of Development • Lewis Wolpert, Jim Smith• ISBN 9780198800569
Vorschau 2 aus 8 Seiten
- Discuss the evidence for the nodal morphogen acting during mesoderm induction.
- Discuss the concept of the vertebrate dorsal organiser.
- Discuss the evidence that the brachyury transcription factor is a conserved regulator of germ layer specification.
- Draw conclusions regarding the molecular pathways regulating development of Urbilateria.
- Provide an overview of the polycomb and trithorax group complexes and their activities
- Describe evidence that indicates stem cell chromatin is in an open ‘permissive’ state
- Understand what is bivalent chromatin and why it may be important for stem cell biology and development
- Understand the steps of chromatin immunoprecipitation and why it is a useful technique in epigenetic studies
- Describe the Nodal signalling example and experimental approach, and understand how it illustrates ...
- Book
- Notizen
- • 9 Seiten 's •
-
The University of York•Molecular Genetics and Development
-
Principles of Development • Lewis Wolpert, Jim Smith• ISBN 9780198800569
Vorschau 2 aus 9 Seiten
- Provide an overview of the polycomb and trithorax group complexes and their activities
- Describe evidence that indicates stem cell chromatin is in an open ‘permissive’ state
- Understand what is bivalent chromatin and why it may be important for stem cell biology and development
- Understand the steps of chromatin immunoprecipitation and why it is a useful technique in epigenetic studies
- Describe the Nodal signalling example and experimental approach, and understand how it illustrates ...
- Describe experiments that defined compartments of cell lineage restriction.
- Define a compartment and describe the evidence showing that the parasegment is a compartment and the developmentally important unit of the fly.
- Describe genetic experiments demonstrating that HOM-C genes regulate parasegment identity in Drosophila.
- Evaluate whether the vertebrate Hox genes share a conserved function with Drosophila HomC genes
- Book
- Notizen
- • 8 Seiten 's •
-
The University of York•Molecular Genetics and Development
-
Principles of Development • Lewis Wolpert, Cheryll Tickle• ISBN 9780199678143
Vorschau 2 aus 8 Seiten
- Describe experiments that defined compartments of cell lineage restriction.
- Define a compartment and describe the evidence showing that the parasegment is a compartment and the developmentally important unit of the fly.
- Describe genetic experiments demonstrating that HOM-C genes regulate parasegment identity in Drosophila.
- Evaluate whether the vertebrate Hox genes share a conserved function with Drosophila HomC genes
- Identify the important signalling centres in the developing limb bud and describe the experiments that identified these centres and demonstrated their importance.
- Describe the experimental evidence for the role of FGF signalling in limb bud outgrowth
- Describe the experimental evidence that shows that Shh acts as a morphogen to pattern the anterior-posterior axis of the limb bud.
- Describe how the important signalling centres in the limb bud co-ordinately regulate pattern formation in the ...
- Book
- Notizen
- • 7 Seiten 's •
-
The University of York•Molecular Genetics and Development
-
Principles of Development • Lewis Wolpert, Jim Smith• ISBN 9780198800569
Vorschau 2 aus 7 Seiten
- Identify the important signalling centres in the developing limb bud and describe the experiments that identified these centres and demonstrated their importance.
- Describe the experimental evidence for the role of FGF signalling in limb bud outgrowth
- Describe the experimental evidence that shows that Shh acts as a morphogen to pattern the anterior-posterior axis of the limb bud.
- Describe how the important signalling centres in the limb bud co-ordinately regulate pattern formation in the ...
- Appreciate and describe the molecular mechanisms underlying neural induction
- Describe TGF-beta (TGF-β) signal transduction and the differences between the BMP versus nodal pathways
- Discuss the experiments that demonstrate a role for BMP antagonists in vertebrate neural induction
- Describe how antisense morpholino oligos can be used to inhibit gene function
- Appreciate and describe the differences between the processes of neural induction versus neurogenesis
- Book
- Notizen
- • 6 Seiten 's •
-
The University of York•Molecular Genetics and Development
-
Principles of Development • Lewis Wolpert, Jim Smith• ISBN 9780198800569
Vorschau 2 aus 6 Seiten
- Appreciate and describe the molecular mechanisms underlying neural induction
- Describe TGF-beta (TGF-β) signal transduction and the differences between the BMP versus nodal pathways
- Discuss the experiments that demonstrate a role for BMP antagonists in vertebrate neural induction
- Describe how antisense morpholino oligos can be used to inhibit gene function
- Appreciate and describe the differences between the processes of neural induction versus neurogenesis
-Describe the hierarchy of gene activity that regulates Drosophila segmentation
-Distinguish and explain methods used to investigate protein vs mRNA expression
-Describe the syncytial nature of the early stages of fly development and understand its significance.
-Understand and describe at the molecular level how the Gap genes regulate the expression of Eve stripe 2
-Make predictions about segment polarity gene expression in a pair-rule mutant embryo or about pair-rule gene expression in a Gap m...
- Book
- Notizen
- • 7 Seiten 's •
-
The University of York•Molecular Genetics and Development
-
Principles of Development • Lewis Wolpert, Jim Smith• ISBN 9780198800569
Vorschau 2 aus 7 Seiten
-Describe the hierarchy of gene activity that regulates Drosophila segmentation
-Distinguish and explain methods used to investigate protein vs mRNA expression
-Describe the syncytial nature of the early stages of fly development and understand its significance.
-Understand and describe at the molecular level how the Gap genes regulate the expression of Eve stripe 2
-Make predictions about segment polarity gene expression in a pair-rule mutant embryo or about pair-rule gene expression in a Gap m...
- Understand how the neural crest contributes to cardiac development and the pathology underlying congenital cardiac abnormalities.
- Explain how certain SNPs might contribute to congenital abnormalities.
- Discuss the evidence that Notch signalling is important during cardiac morphogenesis
- Book
- Notizen
- • 10 Seiten 's •
-
The University of York•Molecular Genetics and Development
-
Principles of Development • Lewis Wolpert, Jim Smith• ISBN 9780198800569
Vorschau 2 aus 10 Seiten
- Understand how the neural crest contributes to cardiac development and the pathology underlying congenital cardiac abnormalities.
- Explain how certain SNPs might contribute to congenital abnormalities.
- Discuss the evidence that Notch signalling is important during cardiac morphogenesis
- Discuss the evidence supporting a role for tinman homologues in heart development
- Discuss the anatomical and molecular evidence supporting the theory of dorsoventral axis inversion during the evolution of protostome and deuterostome lineages.
- Describe the conserved features of Hox gene cluster organisation.
- Appreciate and discuss how changes in the expression and activity of Hox genes have contributed to changes in anatomy during animal evolution.
- Draw conclusions regarding the molecul...
- Book
- Notizen
- • 7 Seiten 's •
-
The University of York•Molecular Genetics and Development
-
Principles of Development • Lewis Wolpert, Jim Smith• ISBN 9780198800569
Vorschau 2 aus 7 Seiten
- Discuss the evidence supporting a role for tinman homologues in heart development
- Discuss the anatomical and molecular evidence supporting the theory of dorsoventral axis inversion during the evolution of protostome and deuterostome lineages.
- Describe the conserved features of Hox gene cluster organisation.
- Appreciate and discuss how changes in the expression and activity of Hox genes have contributed to changes in anatomy during animal evolution.
- Draw conclusions regarding the molecul...
- Describe the different types of animal body symmetry and the main body axes of bilaterally symmetrical animals.
- Describe the features that define diploblasts versus triploblasts.
- Describe the features that define protostomes versus deuterostomes.
- Understand the importance of the Ediacaran and Cambrian fauna in animal evolution.	
- Describe the common features of phylotypic stage chordate embryos.
- Discuss the evidence indicating that Pax6 is a conserved regulator of eye development. 
- ...
- Book
- Notizen
- • 7 Seiten 's •
-
The University of York•Molecular Genetics and Development
-
Principles of Development • Lewis Wolpert, Jim Smith• ISBN 9780198800569
Vorschau 2 aus 7 Seiten
- Describe the different types of animal body symmetry and the main body axes of bilaterally symmetrical animals.
- Describe the features that define diploblasts versus triploblasts.
- Describe the features that define protostomes versus deuterostomes.
- Understand the importance of the Ediacaran and Cambrian fauna in animal evolution.	
- Describe the common features of phylotypic stage chordate embryos.
- Discuss the evidence indicating that Pax6 is a conserved regulator of eye development. 
- ...