The claisen condensation Study guides, Class notes & Summaries

CHEM 239 Organic Chemistry - University of Washington. Quiz Section _ Chapter 22 WorksheetChem 239 Chapter 22 Worksheet Work in groups of 3-4 to solve the following problems. Some of these questions are meant to be challenging and to encourage a productive discussion with your groupmates. This worksheet is substantially longer than 50 minutes and is designed to provide extra practice for you after the quiz section. Complete at least 2 questions to earn participation credit. Make sure all group m...

Orgo 2223B final-lipids Summary Questions and Answers Are lipids soluble or insoluble in water? - CORRECT ANSWER-insoluble What type of double bonds do naturally occurring fatty acids have? - CORRECT ANSWER-cis When fatty acids are added to water, do the majority of them remain ionized or nonionized? - CORRECT ANSWER-nonionized What is the name of the reaction for the synthesis of fatty acids? - CORRECT ANSWER-Claisen condensation What type of reaction is a Claisen condensation? - C...

The Claisen condensation produces which of these? a) An ∝-keto ester b) A β-keto ester c) A β-hydroxy ester d) A β-hydroxyaldehyde e) A β-diketone Answer: B Topic: General Information Section: 19.2 Difficulty Level: Easy 2) Cyclization reactions, such as the Dieckmann condensation, are best carried out using fairly dilute solutions of the compound to be cyclized. Why is this so? a) It then is possible to use less base. b) The reagents generally are expensive. c) A smaller amo...

This chapter contains all necessary information needed to know about the alpha carbon chemistry of carbonyl compounds. These notes are color coded. It contains information about acidity, enolization, alpha halogenation, aldol and claisen condensation reactions, malonic and acetoacetic ester synthesis, conjugate addition and michael addition reactions. Reactions and mechanisms are shown clearly with arrows, and explanations as necessary.

1. If the delta G'° of the reaction A --> B is -40 kJ/mol, under standard conditions the reaction: A) is at equilibrium. B) will never reach equilibrium. C) will not occur spontaneously. D) will proceed at a rapid rate. E) will proceed spontaneously from A to B. E For the reaction A --->B, delta G'° = -60 kJ/mol. The reaction is started with 10 mmol of A; no B is initially present. After 24 hours, analysis reveals the presence of 2 mmol of B, 8 mmol of A. Which is the mo...

Enol Enolates and Enamines: Enol Enolates: These are formed by deprotonating an alpha carbon adjacent to a carbonyl group in a molecule containing both a carbonyl and an enolizable proton. They are important intermediates in many organic reactions, particularly in aldol condensation and Claisen condensation reactions. Enamines: These are formed by the reaction of a secondary amine with a carbonyl compound, resulting in the formation of a carbon-nitrogen double bond. Enamines are versatile ...

--NO2 + Sn/HCl - Correct Answers>Clemmenson Reduction --NH2 1,2-addition conj double bonds + RMgX or LiAlH4 - Correct Answers>Nucleophiles attack the carbonyl directly. Strong nucleophiles: Gringards, NaBH4, LiAlH4 1. (2) esters CH3--C=O--OEt + NaOR, EtOH 2. H3O+ ketone + (ester) CH3--C=O--OEt + -OR + H3O+ --> - Correct Answers>Claisen Condensation enolate ion of one ester acts as nucleophile attacking another ester 1. NaOR, EtOH 2. H3O+ Anhydride for mixed 1. BH3/TH...

CHEM 309 Organic Chemistry II homework 10 With Completed Solutions- Boise State University Acid chlorides are the most reactive carboxylic acid derivatives. Provide curved arrows to complete t he following reaction mechanism for attack of a typical neutral nucleophile to an acid chloride. Remember the rules for drawing curved arrows: begin each arrow at a bond or lone pair (draw them in) and end each arrow at an atom or bond. lb) When neutral nucleophiles react with acid chlorides or anhydrides-...

This document is a summary of the alpha carbon chemistry chapter of the organic chemistry 2 course. It is digitally taken handwritten notes. This chapter contains all necessary information needed to know about the alpha carbon chemistry of carbonyl compounds. These notes are color coded. It contains information about acidity, enolizations, alpha halogenations, aldol and claisen condensation reactions, malonic and acetoacetic ester synthesis, conjugate addition and michael addition reactions. Rea...

Notes about Claisen Condensation (analogous to Aldol condensations) and Dieckmann reactions.