Phr 911 block 2 Study guides, Class notes & Summaries

The purpose of phase 1 was to produce metabolites with functional groups or ________ _____________ correct answer: chemical handles The purpose of phase 2 is to introduce glucuronic acid, sulfate ions, acetyl groups, amino acids, or methyl groups with the goal of generating a hydrophilic conjugate for ________________. correct answer: excretion What are the most important conjugation enzymes? correct answer: UDP glucuronoyltransferases (UGTs), sulfotransferases (STs), glutathione S-tran...

fate of drugs correct answer: Absorption Distribution Metabolism Elimination pharmacokinetics correct answer: what the body does to the drug pharmacodynamics correct answer: what the drug does to the body what happens during pharmacokinetics (metabolism) correct answer: -enzymes convert active drug to inactive metabolites for excretion -enzymes convert inactive drugs (prodrugs) to active drugs -enzymes convert active drugs to active metabolites (metabolites may have a different...

Pharmacokinetics correct answer: What the body does to the drug Pharmacodynamics correct answer: What the drug does to the body ADME correct answer: Absoprtion-Distribution-Metabolism-Elimination Xenobiotics correct answer: Comprise the set of all chemicals not normally found in humans (exogenous) It is not typically found in humans correct answer: What statement best describes why codeine is a xenobiotic? Genetics, physiology, pharmacodynamics, environment correct answer: F...

ADME correct answer: Absorption Distribution Metabolism Elimination When a drug is absorbed, it can be one of 2 things correct answer: 1. Free drug (unbound, active and can readily cross cell membranes) 2. Protein-bound (usually inactive) Binding of drugs to receptors correct answer: Non-specific binding <——> specific binding —> desired biological effect **Distribution** Pharmacokinetics correct answer: Metabolism and elimination -what the body does to the dru...

PHR/SPHR Terms Exam 282 Questions with Verified Answers B. aPHR C. SHRM-CP D. IPMA-SCP F. SPHR-SCP - CORRECT ANSWER 1. Which of the following are valid HR certifications? A. SPHRca B. aPHR C. SHRM-CP D. IPMA-SCP E. Intern-CP F. SPHR-SCP Human Resource Certification Institute (HRCI) - CORRECT ANSWER 1. ______________ was accredited by the National Commission for Certifying Agencies (NCCA) in 2008. A. SHPRi - (1) HRCI B. aPHR - (1) HRCI C. SHRM-SCP - (2) D. IPMA-CP - (3) - CO...

PHR/SPHR Terms Exam 282 Questions with Verified Answers B. aPHR C. SHRM-CP D. IPMA-SCP F. SPHR-SCP - CORRECT ANSWER 1. Which of the following are valid HR certifications? A. SPHRca B. aPHR C. SHRM-CP D. IPMA-SCP E. Intern-CP F. SPHR-SCP Human Resource Certification Institute (HRCI) - CORRECT ANSWER 1. ______________ was accredited by the National Commission for Certifying Agencies (NCCA) in 2008. A. SHPRi - (1) HRCI B. aPHR - (1) HRCI C. SHRM-SCP - (2) D. IPMA-CP - (3) - CO...