Lewis wolpert Samenvattingen, Notities en Examens

- Identify the important signalling centres in the developing limb bud and describe the experiments that identified these centres and demonstrated their importance. - Describe the experimental evidence for the role of FGF signalling in limb bud outgrowth - Describe the experimental evidence that shows that Shh acts as a morphogen to pattern the anterior-posterior axis of the limb bud. - Describe how the important signalling centres in the limb bud co-ordinately regulate pattern formation in the ...

- Describe the different types of animal body symmetry and the main body axes of bilaterally symmetrical animals. - Describe the features that define diploblasts versus triploblasts. - Describe the features that define protostomes versus deuterostomes. - Understand the importance of the Ediacaran and Cambrian fauna in animal evolution. - Describe the common features of phylotypic stage chordate embryos. - Discuss the evidence indicating that Pax6 is a conserved regulator of eye development. - ...

- Discuss the evidence supporting a role for tinman homologues in heart development - Discuss the anatomical and molecular evidence supporting the theory of dorsoventral axis inversion during the evolution of protostome and deuterostome lineages. - Describe the conserved features of Hox gene cluster organisation. - Appreciate and discuss how changes in the expression and activity of Hox genes have contributed to changes in anatomy during animal evolution. - Draw conclusions regarding the molecul...

- Appreciate and describe the molecular mechanisms underlying neural induction - Describe TGF-beta (TGF-β) signal transduction and the differences between the BMP versus nodal pathways - Discuss the experiments that demonstrate a role for BMP antagonists in vertebrate neural induction - Describe how antisense morpholino oligos can be used to inhibit gene function - Appreciate and describe the differences between the processes of neural induction versus neurogenesis

- Describe the experimental evidence supporting a conserved pathway for regulating neurogenesis in animals - Discuss the conserved function of proneural genes in neurogenesis - Discuss the conserved function of neurogenic genes in neurogenesis - Describe the role of lateral inhibition in selecting neural precursors - Describe the conserved role of notch-delta signalling in mediating lateral inhibition - Appreciate and discuss the distinct processes of neural induction, neurogenesis and neurulati...

Summary molecular principles of development lecture 1-6. You can purchase the bundle 'molecular principles of development' to get the summary of all lectures and an overview of key concepts for the exam.

Summary molecular principles of development lecture 7-11. You can purchase the bundle 'molecular principles of development' to get the summary of all lectures and an overview of key concepts for the exam.

This document can be used as extra study material and consists of all the main topic you should know for the exam. These concepts refer to the summary of molecular principles of development which is also available.

Summary Molecular Principles of Development Includes lectures and a summary of the book Principles of Developmet (Wolpert et al.).

this is a chapter one note of the book the unnatural nature of science and it includes each section of the first chapter into notes please enjoy gives a handful of information that explains the first chapter