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CMN 554 Unit 1 Part 2 Questions and Answers What are the clinical features of patients with Down Syndrome? ANSWER -hypotonia -upward-slanted palpebral fissures -midface depression -flat wide nasal bridge -simian crease -short stature -increased incidence of thyroid abnormalities -congenital heart disease -BEHAVIORAL PHENOTYPE includes passive, affable, hyperactivity in childhood, stubborn, verbal > auditory processing, increased risk of depression, and dementia of the Alzheimer ty...