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NURS 5315 Test 2 Mod 3

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NURS 5315 Test 2 Mod 3

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NURS 5315
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NURS 5315

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NURS 5315 Test 2 Mod 3



Organs of the immune system - Answer ✔✔ - - bone marrow
- thymus
- spleen
- lymph nodes, tonsils, peyer patches

Bone marrow function in immune system - Answer ✔✔ - Responsible for production
of immune cells and the maturation of B cells

Thymus function in immune system - Answer ✔✔ - Provides site for t-cell
differentiation, maturation and selection (shrinks as we grow)

Spleen function in immune system - Answer ✔✔ - contains blood filled sinuses that
filter antigens and cells from the blood
- red pulp (red blood cell storage and turnover)
- white pulp (where immune cell interaction occurs)
- those w/o spleen at increased risk for infection

Lymph nodes function in immune system - Answer ✔✔ - antigens interaction with
immune cells

5 types of immunity - Answer ✔✔ - 1. Natural (Innate resistance)
2. Active Acquired
3. Passive Acquired
4. Humoral
5. Cell-mediated

Normal function of T-lymphocyte - Answer ✔✔ - - develop into several subsets that
identify and kill target cell (t-cytoxic)
- regulate immune response by helping clonal selection process (t-helper)
- Suppress/limit immune response (t-regulatory)

Normal function of B-lymphocyte - Answer ✔✔ - develop into plasma cells that
produce antibody

Natural Immunity AKA innate resistance immunity - Answer ✔✔ -

Active Acquired Immunity - Answer ✔✔ - Produced by host after exposure to an
antigen (basis of vaccinations)

, NURS 5315 Test 2 Mod 3



Passive Acquired Immunity - Answer ✔✔ - acquired via the transfer of antibodies or
T-cells to recipient (mother to fetus, rabies)

Humoral Immunity - Answer ✔✔ - conferred by B-cells; provides immunity against
some viral infections, toxin induced diseases and diseases caused by
pneumococci/meningicocci/hemophilus

Cell-mediated Immunity - Answer ✔✔ - conferred by T-cells; active against cells
infected with IC bacteria or virues; responsible for organ transplantation rejection

Antigen (def) - Answer ✔✔ - describes a molecule that can reach with binding sites on
antibodies or antigen receptors on B&T cells

Self-antigen (def) - Answer ✔✔ - part of individual's makeup that fulfills all criteria
EXCEPT foreignness and does not normally elicit immune response

Allergen (def) - Answer ✔✔ - Antigen that induces allergic response

IgA function - Answer ✔✔ - Main immune globulin in secretions and mucous
membranes; prevents attachment of microorganisms to mucous membranes

IgM function - Answer ✔✔ - Main immune globulin produced EARLY in primary
immune response (high level indicates recent infection)

IgG function - Answer ✔✔ - Most prominent; binds with viruses, bacteria and toxins;
activates complement and binds to macrophages; primary antibody in secondary
immune response; levels increase in response to repeated exposure to antigen; only
one that crosses placenta

IgE function - Answer ✔✔ - Binds to mast cells, eosinophils, basophils; involved in
parasitic infection and hypersensitivity reactions

T-cytoxic cells (CD8) AKA Killer T's - Answer ✔✔ - Kill virus infected cells, tumor cells
and transplant tissue directly through the release of cytotoxic chemicals which destroy
the cell membrane or induce apoptosis

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