BPS 2110 - Final Exam

What is the goal of Phase 1 of Clinical Trials? - Answer- Dose Finding How many patients are involved in Phase 1 of Clinical Trials? - Answer- Small number (100) What type of patients are involved in Phase 1 of Clinical Trials? - Answer- Healthy volunteers What is the average time taken for Phase 1 of Clinical Trials? - Answer- 1 year What is the drug failure rate of Phase 1 of Clinical Trials? - Answer- 30% What is the goal of Phase 2 of Clinical Trials? - Answer- Safety and efficacy How many patients are involved in Phase 2 of Clinical Trials? - Answer- Medium number (~200-300) What type of patients are involved in Phase 2 of Clinical Trials? - Answer- Patients What is the average time taken for Phase 2 of Clinical Trials? - Answer- ~1 year What is the drug failure rate of Phase 2 of Clinical Trials? - Answer- ~70% What is the goal of Phase 3 of Clinical Trials? - Answer- Find rare side effects How many patients are involved in Phase 3 of Clinical Trials? - Answer- Large number (~1000) What is the average time taken for Phase 3 of Clinical Trials? - Answer- ~1 year What type of patients are involved in Phase 3 of Clinical Trials? - Answer- Patients What is the drug failure rate of Phase 3 of Clinical Trials? - Answer- ~70% What are the two general types of large pharmaceutical companies? - Answer- Ethical pharmaceutical companies and generic pharmaceutical companies What are ethical pharmaceutical companies? - Answer- Companies that invest heavily in research. They discover and develop new molecular entities. What are generic pharmaceutical companies? - Answer- They focus on breaking/ adapting p