Chemokine Guides d'étude, Notes de cours & Résumés

Molecular Drug Targets - ANSWER-Receptors-45% Enzymes-28% Hormones-11% Unknown-7% Ion Channels-5% DNA-4% Channel-Linked (Ionotropic) Receptors - ANSWER-Produce cellular effects in milliseconds Nicotinic ACh receptor GPCRs - ANSWER-Effects happen in seconds Muscarinic ACh receptor Kinase-linked receptors - ANSWER-Effects happen in minutes Insulin receptor Receptors linked to gene transcription - ANSWER-Effects happen in hours Estrogen receptor Heterotrimeric G proteins - A...

This document consists of a summary of the course Drug Target Biochemistry and Signaling, corresponding to the Master Drug Discovery Sciences.

-Chemotaxis -Margination or pavementing ---> selectins and chemokine receptors "grab" neutrophils on vessel walls -Diapedesis or emigration of neutrophils into tissue Correct Answer-What happens w/ the Emigration of Leukocytes? -infection -mechanical damage -ischemia -nutrient deprivation -temperature extremes -radiation -etc... Correct Answer-General causes of inflammation -prevent infection and damage by microorganisms -dilute toxins -activate plasma protein systems -lim...

Which of the following medications should a patient taking cyclosporine avoid following an allogenic HSCT? A. Torsemide B. Bumetanide C. Spironolactone D. Furosemide - Answer- C. Patients taking cyclosporine should avoid potassium sparing diuretics such as spironolactone. How is bronchiolitis obliterans diagnosed? A. Pulmonary function test B. Bronchoalveolar lavage C. Computed tomography scan D. Chest x-ray - Answer- A. Pulmonary function test. Used to diagnose bronchiolitis oblitera...

BMTCN TEST A LATEST 2024 ACTUAL QUESTIONS AND ANSWERS ALREADY GRADED A+ Immunoglobulins are secreted by which type of cell? A. B-lymphocyte B. Megakaryocyte C. T-lymphocyte D. Natural killer Ans- A. B-lymphocyte B lymphocytes synthesize and secrete immunoglobulins. Which portion of the immunoglobulin activates the complement pathway? A. MHC Class I B. Fab C. Fc D. MHC Class II Ans- C. Fc The Fc region activates the complement pathway. Which of the following is a ...

[WARNING: INVALID] 1. What does this experiment tell us? Choose ALL that apply. A. Both B cells and T cells can produce antibodies. B. Both B cells and T cells have memory functions. C. Both B cells and T cells are required for an antibody response. D. B cells are required for an antibody response in the absence of T cells. E. B cells and T cells are co-localized and produce synergetic effects in bone marrow and thymus. correct answersanswer: c type: x 2. In 2090, a human popula...

BMTCN TEST B ACTUAL QUESTIONS AND ANSWERS 2024 GRADED A+ Transplant-related toxicity is a barrier that contributes to the under utilization for which of the following diseases? A. Non-Hodgkin lymphoma B. Acute myeloid leukemia C. Sickle cell disease D. Neuroblastoma Ans- C. Sickle cell disease Despite success of HSCT in sickle cell disease, barriers to successful HSCT include lack of a suitable donor, transplant related toxicity and immunologic graft rejection. Which of the foll...

erythrocyte, platelets, neutrophil, basophil, eosinophil, monoblast, macrophage, monocyte Myeloid pre- B cell, pre-t cell, plasma cell, natural killer cell, t lymphocyte lymphoid occurs naturally- phagocytes release inflammatory mediators innate immunity response of either b or t cells to antigens acquired immunity loss of cells power to divide and grow senescence reduction in size of thymus and function of immune cells immunosenescence myeloid fi...

Which of the following medications should a patient taking cyclosporine avoid following an allogenic HSCT? A. Torsemide B. Bumetanide C. Spironolactone D. Furosemide - C. Patients taking cyclosporine should avoid potassium sparing diuretics such as spironolactone. How is bronchiolitis obliterans diagnosed? A. Pulmonary function test B. Bronchoalveolar lavage C. Computed tomography scan D. Chest x-ray - A. Pulmonary function test. Used to diagnose bronchiolitis obliterans. Which of th...

BMTCN Test B Question and answers correctly solved 2023/2024Transplant-related toxicity is a barrier that contributes to the underutilization for which of the following diseases? A. Non-Hodgkin lymphoma B. Acute myeloid leukemia C. Sickle cell disease D. Neuroblastoma - correct answer C. Sickle cell disease Despite success of HSCT in sickle cell disease, barriers to successful HSCT include lack of a suitable donor, transplant related toxicity and immunologic graft rejection. Which ...