Chapter 5. Adverse Drug Reactions
Multiple Choice
Identify the choice that best completes the statement or answers the question.
1. Which of the following patients would be at higher risk of experiencing adverse drug reactions
(ADRs):
1. A 32-year-old male
2. A 22-year-old female
3. A 3-month-old female
4. A 48-year-old male
2. Infants and young children are at higher risk of ADRs due to:
1. Immature renal function in school-age children
2. Lack of safety and efficacy studies in the pediatric population
3. Children’s skin being thicker than adults, requiring higher dosages of topical
medication
4. Infant boys having a higher proportion of muscle mass, leading to a higher volume
of distribution
3. The elderly are at high risk of ADRs due to:
1. Having greater muscle mass than younger adults, leading to higher volume of
distribution
2. The extensive studies that have been conducted on drug safety in this age group
3. The blood-brain barrier being less permeable, requiring higher doses to achieve
therapeutic effect
4. Age-related decrease in renal function
4. The type of adverse drug reaction that is idiosyncratic when a drug given in the usual therapeutic
doses is type:
, 1. A
2. B
3. C
4. D
5. Digoxin may cause a type A adverse drug reaction due to:
1. Idiosyncratic effects
2. Its narrow therapeutic index
3. Being a teratogen
4. Being a carcinogen
6. Sarah developed a rash after using a topical medication. This is a type allergic drug reaction.
1. I
2. II
3. III
4. IV
7. A patient may develop neutropenia from using topical Silvadene for burns. Neutropenia is a(n):
Multiple Choice
Identify the choice that best completes the statement or answers the question.
1. Which of the following patients would be at higher risk of experiencing adverse drug reactions
(ADRs):
1. A 32-year-old male
2. A 22-year-old female
3. A 3-month-old female
4. A 48-year-old male
2. Infants and young children are at higher risk of ADRs due to:
1. Immature renal function in school-age children
2. Lack of safety and efficacy studies in the pediatric population
3. Children’s skin being thicker than adults, requiring higher dosages of topical
medication
4. Infant boys having a higher proportion of muscle mass, leading to a higher volume
of distribution
3. The elderly are at high risk of ADRs due to:
1. Having greater muscle mass than younger adults, leading to higher volume of
distribution
2. The extensive studies that have been conducted on drug safety in this age group
3. The blood-brain barrier being less permeable, requiring higher doses to achieve
therapeutic effect
4. Age-related decrease in renal function
4. The type of adverse drug reaction that is idiosyncratic when a drug given in the usual therapeutic
doses is type:
, 1. A
2. B
3. C
4. D
5. Digoxin may cause a type A adverse drug reaction due to:
1. Idiosyncratic effects
2. Its narrow therapeutic index
3. Being a teratogen
4. Being a carcinogen
6. Sarah developed a rash after using a topical medication. This is a type allergic drug reaction.
1. I
2. II
3. III
4. IV
7. A patient may develop neutropenia from using topical Silvadene for burns. Neutropenia is a(n):
