NR546 Week 2: test your knowledge quiz
Pharmacokinetics...Answer is... the study of what happens to a drug from the time of
administration until the parent drug and all metabolites leave the body
Pharmacokinetics concepts...Answer is... absorption
distribution
metabolism
excretion
Flockhart Table...Answer is... drug interactions that are mediated by cytochrome P450 enzymes
comprehensive list of drugs and the interactions related to the cytochrome P450 system
client factors that impact the effect of psychotropic medications...Answer is... -age
-diet
-smoking status
-other prescribed medications
-over-the-counter medications
*all impact drug metabolism
Neurotransmitters...Answer is... chemicals released by neurons to send communication across
synaptic clefts to other neurons
-impact human emotion and behavior
Many psychiatric disorders and client symptoms occur from an excess, deficiency, or imbalance
of _________...Answer is... neurotransmitters
Neurotransmission:...Answer is... the chemical transmission of information between neurons
and their target cells
, -the chemicals, or neurotransmitters, are released from their transport vesicles to bind with
receptor sites to perform their duties, which are excitatory or inhibitory
-neurotransmitter then either returned and stored for future use (reuptake) or inactivated and
dissolved by enzymes
Excitatory neurotransmitters:...Answer is... increase the likelihood that the neuron will fire an
action potential
inhibitory neurotransmitters:...Answer is... decrease the likelihood that a neuron will fire an
action
neurotransmitters that most impact mental health can be classified into four major
categories:...Answer is... cholinergics
-acetylcholine
monoamines
-norepinephrine, dopamine, serotonin, histamine
amino acids
-gamma- amino-butyric acid and glutamate
neuropeptides
Inhibitors: VISA CKGQ...Answer is... Valproate
Isoniazid
Sulfonamides
Amiodarone
Chloramphenicol
Ketoconazole
Grapefruit Juice
Quinidine
-decrease medication metabolism
Pharmacokinetics...Answer is... the study of what happens to a drug from the time of
administration until the parent drug and all metabolites leave the body
Pharmacokinetics concepts...Answer is... absorption
distribution
metabolism
excretion
Flockhart Table...Answer is... drug interactions that are mediated by cytochrome P450 enzymes
comprehensive list of drugs and the interactions related to the cytochrome P450 system
client factors that impact the effect of psychotropic medications...Answer is... -age
-diet
-smoking status
-other prescribed medications
-over-the-counter medications
*all impact drug metabolism
Neurotransmitters...Answer is... chemicals released by neurons to send communication across
synaptic clefts to other neurons
-impact human emotion and behavior
Many psychiatric disorders and client symptoms occur from an excess, deficiency, or imbalance
of _________...Answer is... neurotransmitters
Neurotransmission:...Answer is... the chemical transmission of information between neurons
and their target cells
, -the chemicals, or neurotransmitters, are released from their transport vesicles to bind with
receptor sites to perform their duties, which are excitatory or inhibitory
-neurotransmitter then either returned and stored for future use (reuptake) or inactivated and
dissolved by enzymes
Excitatory neurotransmitters:...Answer is... increase the likelihood that the neuron will fire an
action potential
inhibitory neurotransmitters:...Answer is... decrease the likelihood that a neuron will fire an
action
neurotransmitters that most impact mental health can be classified into four major
categories:...Answer is... cholinergics
-acetylcholine
monoamines
-norepinephrine, dopamine, serotonin, histamine
amino acids
-gamma- amino-butyric acid and glutamate
neuropeptides
Inhibitors: VISA CKGQ...Answer is... Valproate
Isoniazid
Sulfonamides
Amiodarone
Chloramphenicol
Ketoconazole
Grapefruit Juice
Quinidine
-decrease medication metabolism
