GUIDE
ADVANCED
PATHOPHYSIOLOGY
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NR507 – Advanced Pathophysiology
Exam Study Guide – Final Study Guide
Exam Format: Cumulative
Question Type: Multiple Choice
Number of Questions: 100
Time Allotted: 120 minutes
Testing Timeframe: The final exam will only be available
starting on Wednesday Week 8 at 12:01 am MT until
Saturday Week 8 at 11:59 pm MT.
1. Exam CoverageContent Areas:
• Week 5: Gastrointestinal and Neurobiological
Pathologies
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• Week 6: Endocrine Pathologies
• Week 7: CNS Sensory and Motor Pathologies
• Week 8: Brain and Dermatological Pathologies
2. Key Concepts to Study
Gastrointestinal pathologies:
Pathophysiology of GERD
Gastroesophageal reflux disease (GERD) occurs when the
lower esophageal sphincter (LES) becomes weakened or
relaxes inappropriately, allowing gastric acid to reflux
into the esophagus. Chronic exposure to acid causes
mucosal inflammation, irritation, and possible erosion.
Signs and Symptoms of GERD
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Common symptoms include heartburn, regurgitation,
chest pain, dysphagia, chronic cough, and hoarseness,
particularly after meals or when lying down.
Pharmacologic Management of GERD
Treatment includes proton pump inhibitors (PPIs) such as
omeprazole, H2 receptor antagonists like famotidine, and
antacids for symptomatic relief. Prokinetic agents may be
used in selected cases.
Risk Factors for Esophageal Stricture
Chronic GERD, prolonged acid exposure, esophageal
injury, radiation therapy, or ingestion of caustic
substances can lead to fibrosis and narrowing of the
esophagus.
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