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Epidemiology Exam - Clostridia: Tetanus and Botulism Overview With complete solution–Expert Verified | Latest Questions 2025

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Epidemiology Exam - Clostridia: Tetanus and Botulism Overview With complete solution–Expert Verified | Latest Questions 2025

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Epidemiology Exam - Clostridia: Tetanus and Botulism
Overview With complete solution–Expert Verified | Latest
Questions 2025


Clostridium tetani - Causes tetanus via tetanospasmin exotoxin.


Clostridium botulinum - Produces botulinum toxin causing flaccid paralysis.


Clostridium perfringens - Causes gas gangrene and food poisoning.


Tetanus toxin - Protease cleaving SNARE proteins in neurotransmission.


Botulinum toxin - Inhibits ACh release at neuromuscular junction.


Tetanospasmin - Exotoxin causing spastic paralysis and muscle spasms.


Spastic paralysis - Muscle stiffness and spasms due to toxin.


Trismus - Lockjaw symptom of tetanus infection.


Risus sardonicus - Facial expression of raised eyebrows and grin.


Opisthotonos - Spasms of spinal extensors causing arching.


GABA - Inhibitory neurotransmitter blocked by tetanospasmin.

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