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"NR 508 Final Exam Review: Advanced Pharmacology Practice Questions and Answers"

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This document is a comprehensive review resource for the NR 508 Advanced Pharmacology course, commonly part of Nurse Practitioner (NP) programs. It contains a large set of multiple-choice questions (MCQs) with clearly indicated correct answers, focused on preparing students for the final exam in pharmacology.

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Uploaded on
July 4, 2025
Number of pages
105
Written in
2024/2025
Type
Exam (elaborations)
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Questions & answers

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NR 508 Final Review Questions

________ should be monitored when vitamin B12 therapy is started.
1. Serum calcium 2. Serum potassium 3. Ferritin 4. C-reactive
protein - Serum potassium . As drugs near the end of their patent,
pharmaceutical companies may apply for the drug to change to
over-the-counter status in order to: 1. Get a new patent for the
over-the-counter form of the drug 2. Lower the costs because most
prescription benefit plans do not cover generics 3. Market the drug
to a whole new population, as they are able to market to patients
instead of just providers 4. Continue to make large profits from
their blockbuster brand-name drug - Continue to make large
profits from their blockbuster brand-name drug . Behaviors
predictive of addiction to controlled substances include: 1. Stealing
or borrowing another patient's drugs 2. Requiring increasing doses
of opiates for pain associated with malignancy 3. Receiving refills of
a Schedule II prescription on a regular basis 4. Requesting that only
their own primary care provider prescribe for them - Stealing or
borrowing another patient's drugs . Clinical dosing of Bethanechol:
1. Begins at the highest effective dose to obtain a rapid response 2.
Starts at 5 mg to 10 mg PO and is repeated every hour until a
satisfactory clinical response is achieved 3. Requires dosing only
once daily 4. Is the same for both the oral and parenteral route -
Starts at 5 mg to 10 mg PO and is repeated every hour until a
satisfactory clinical response is achieved . Isoniazid (INH) may
induce a deficiency of which vitamin? 1. B6 2. C 3. D 4. E - B6 .
Newborns are at risk for early vitamin K deficiency bleeding and
the American Academy of Pediatrics recommends that all
newborns receive: 1. IM vitamin K (phytonadione) within 24 hours
of birth 2. Oral vitamin K supplementation in the first 3 weeks of

,life 3. Formula containing vitamin K or breast milk 4. Oral vitamin
K in the first 24 hours after birth - IM vitamin K (phytonadione)
within 24 hours of birth . Nicotine replacement therapy (NRT): 1.
Is widely distributed in the body only when the gum products are
used 2. Does not cross the placenta and so is safe for pregnant
women 3. Delays healing of esophagitis and peptic ulcers 4. Has no
drug interactions when a transdermal patch is used - Delays
healing of esophagitis and peptic ulcers . Patients who need to
remain alert are taught to avoid which drug due to its
antimuscarinic effects? 1. Levothyroxine 2. Prilosec 3. Dulcolax 4.
Diphenhydramine - Diphenhydramine . Patients with psychiatric
illnesses have adherence rates to their drug regimen between 35%
and 60%. To improve adherence in this population, prescribe drugs:
1. With a longer half-life so that missed doses produce a longer
taper on the drug curve 2. In oral formulations that are more
easily taken 3. That do not require frequent monitoring 4.
Combined with patient education about the need to adhere even
when symptoms are absent - With a longer half-life so that missed
doses produce a longer taper on the drug curve . Phase IV clinical
trials in the United States are also known as: 1. Human
bioavailability trials 2. Postmarketing research 3. Human safety
and efficacy studies 4. The last stage of animal trials before the
human trials begin - Postmarketing research . Phenytoin requires
that a trough level be drawn. Peak and trough levels are done: 1.
When the drug has a wide therapeutic range 2. When the drug will
be administered for a short time only 3. When there is a high
correlation between the dose and saturation of receptor sites 4. To
determine if a drug is in the therapeutic range - To determine if a
drug is in the therapeutic range . Providers have a responsibility for
determining the best plan of care, but patients also have
responsibilities. Patients the provider can be assured will carry
through on these responsibilities include those who: 1. Are well-

,educated and affluent 2. Have chronic conditions 3. Self-monitor
drug effects on their symptoms 4. None of the above guarantee
adherence - None of the above guarantee adherence . Selma, who
is overweight, recently started taking topiramate for seizures and
at her follow-up visit you note she has lost 3 kg. The appropriate
action would be: 1. Tell her to increase her caloric intake to
counter the effects of the topiramate. 2. Consult with a neurologist,
as this is not a common adverse effect of topiramate. 3. Decrease
her dose of topiramate. 4. Reassure her that this is a normal side
effect of topiramate and continue to monitor her weight. -
Reassure her that this is a normal side effect of topiramate and
continue to monitor her weight. . To reduce potential adverse
effects, patients taking a peripherally acting alpha1 antagonist
should do all of the following EXCEPT: 1. Take the dose at bedtime
2. Sit up slowly and dangle their feet before standing 3. Monitor
their blood pressure and skip a dose if the pressure is less than
120/80 4. Weigh daily and report weight gain of greater than 2
pounds in one day - Monitor their blood pressure and skip a dose if
the pressure is less than 120/80 . When a medication is added to a
regimen for a synergistic effect, the combined effect of the drugs is:
1. The sum of the effects of each drug individually 2. Greater than
the sum of the effects of each drug individually 3. Less than the
effect of each drug individually 4. Not predictable, as it varies with
each individual - 2. Greater than the sum of the effects of each
drug individually A 19-year-old female is a nasal Staph aureus
carrier and is placed on 5 days of rifampin for treatment. Her only
other medication is combined oral contraceptives. What education
should she receive regarding her medications? 1. Separate the oral
ingestion of the rifampin and oral contraceptive by at least an hour.
2. Both medications are best tolerated if taken on an empty
stomach. 3. She should use a back-up method of birth control such
as condoms for the rest of the current pill pack. 4. If she gets

, nauseated with the medications she should call the office for an
antiemetic prescription. - She should use a back-up method of
birth control such as condoms for the rest of the current pill pack.
A 19-year-old male was started on risperidone. Monitoring for
risperidone includes observing for common side effects, including: 1.
Bradykinesia, akathisia, and agitation 2. Excessive weight gain 3.
Hypertension 4. Potentially fatal agranulocytosis - Bradykinesia,
akathisia, and agitation A 22-year-old woman receives a
prescription for oral contraceptives. Education for this patient
includes: 1. Counseling regarding decreasing or not smoking while
taking oral contraceptives 2. Advising a monthly pregnancy test for
the first 3 months she is taking the contraceptive 3. Advising that
she may miss two pills in a row and not be concerned about
pregnancy 4. Recommending that her next follow-up visit is in 1
year for a refill and annual exam - Counseling regarding decreasing
or not smoking while taking oral contraceptives A 24-year-old
male received multiple fractures in a motor vehicle accident that
required significant amounts of opioid medication to treat his pain.
He is at risk for a _____ adverse drug reaction when he no longer
requires the opioids. 1. Rapid 2. First-dose 3. Late 4. Delayed -
Late A 56-year-old woman is complaining of vaginal dryness and
dyspareunia. To treat her symptoms with the lowest adverse effects
she should be prescribed: 1. Low-dose oral estrogen 2. A low-dose
estrogen/progesterone combination 3. A vaginal estradiol ring 4.
Vaginal progesterone cream - A vaginal estradiol ring A 66-year-
old male was prescribed phenelzine (Nardil) while in an acute
psychiatric unit for recalcitrant depression. The NP managing his
primary health care needs to understand the following regarding
phenelzine and other monoamine oxidase inhibitors (MAOIs): 1. He
should not be prescribed any serotonergic drug such as sumatriptan
(Imitrex) 2. MAOIs interact with many common foods, including
yogurt, sour cream, and soy sauce 3. Symptoms of hypertensive
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