NBME 17NBME CBSE REAL EXAM 200 QUESTIONS AND ANSWERS LATES
2025 COMPLETE EXAM
Study online at https://quizlet.com/_hh6z54
1. 70yo M dies in a motor vehicle collision. Was undergo- Tubular adenoma or vil-
ing evaluation for occult blood in the stool. Photo of lous polyp. GI blood loss
transverse colon shown. Dx? suggests a risk for malig-
nancy
2. 38yo M truck driver with 1-week hx of watery, itchy Loratadine--> less sedat-
eyes and a runny nose. Physical shows inflamed nasal ing antihistamine
mucosa. No congestion in lower lung. Pharmacother-
apy?
3. 16yo girl with 3-day hx of fever, nonproductive cough, IgM (mono and my-
and fatigue. T 38.3, P 88/min, BP 102-70. PE shows coplasma)
pale conjunctivae. CXR shows bilateral interstitial infil-
trates. Blood spontaenously agglutinates while await-
ing transport to the laboratory. Antibody isotypes
causing agglutination?
4. 24yo M with small tender blisters on his penis 3 days HSV-2
after unprotected sex. Photograph shown. Causal
agent?
5. 42yo F with 3-year hx of an intermittent facial rash, in- Rosacea
cluding the forehead, eyelids, nose, and cheeks. Rash
seems to be getting worse since she moved from
New York to Florida last year. Spicy foods precipitate
a flushing reaction that seems to exacerbate the rash.
PE shows erythema over the nose and cheeks, with
scattered telangiectasias and a few papules. Dx?
6. 53yo M returned from Africa, has fever, headache, Malaria
and abdominal discomfort. Received appropriate vac-
, NBME 17NBME CBSE REAL EXAM 200 QUESTIONS AND ANSWERS LATES
2025 COMPLETE EXAM
Study online at https://quizlet.com/_hh6z54
cinations prior to the trip. T 39.4C. A wright-stained
peripheral smear shown (ring forms in RBCs). Dx?
7. 68yo F with T2DM and hypertension that has been ACE I (Lisinopril)
poorly controlled despite hydrochlorothiazide treat-
ment. BP 150/96, Labs show serum glucose concen-
tration of 130 and proteinuria. In addition to current
Rx, which is most appropriate pharmacotherapy?
8. 66yo M with stage IV colon cancer with 3-day hx of Loperamide
severe diarrhea after receiving chemotherapy with
flourouracil, leucovorin, and irinotecan. Prescribed
opioid antidiarrheal agent with no CNS effects. Which
med?
9. 35yo M in ED with 2-hour hx of sever fatigue and V. Cholerae--> activates AC
dizziness. Had profuse, watery diarrhea for 8 hours
despite a lack of oral intake. Recently returned from
a medical relief trip to a remove village in Honduras.
T 36.7 C, P 122/min, BP 90/50. PE shows dry skin
and decreased capillary refill. Stool for occult blood is
negative; stool is gray and turbid. Gram stain shows
gram-negative, comma-shaped bacteria; no erythro-
cytes of leukocytes. MOA of toxin?
10. 59yo F with gradual onset of lack of muscle control Cerebellum
in her left arm and leg. Sx 1 mo ago after dx with
metastatic breast cancer. PE shows ataxia of left up-
per and lower extremities. Muscle strength, DTR, sen-
sation, proprioception normal. Metastatic tumor in
which location?
, NBME 17NBME CBSE REAL EXAM 200 QUESTIONS AND ANSWERS LATES
2025 COMPLETE EXAM
Study online at https://quizlet.com/_hh6z54
11. Newborn delivered at 38 weeks' gestation weighs Congenital CMV infection
1800 g. PE shows petechial rash, microcephaly, and
hepatosplenomegaly. Serologic test for CMV: IgG + in
mother, + in newborn; IGM - in mother, + in newborn.
Explanation?
12. Female newborn is delivered at 38 weeks' gestation. 15-40; neutral tube closes
Apgar 8 and 8 at 1/5 min. PE shows a bulging, flu- at about 4 weeks
od0filled mass approximately 5 cm in diameter in
the midline over the lumbosacral region. No sponta-
neous movements of the lower extremities. Abnor-
mality most likely occurred because of abnormal de-
velopment during which periods of postconception (in
days)?
13. 64yo M in ED 3 hours after SOB with exertion and ex- Torsades de pointes
treme fatigue. Has ischemic heart disease. P 125/min,
BP 105/60. ECG shows atrial fibrillation. Intravenous
ibutilide is administered. Ten minutes later, ECG shows
normal sinus rhythm. Risk for which drug effect in the
next 6 hours?
14. 65yo F with 20-year hx of osteoarthritis of the hands L3 to L4
now has pain radiating down the distal anterior thigh,
knee, medial leg, and food. Bony outgrowth of ver-
tebrae compressing one of the spinal nerves is sus-
pected. Nerve root in which intervertebral foramina is
effected?
15. 38yo M with 3-year hx of T2DM. Taking an oral antihy- Contemplation
perglycemic agent, he has tried diet and exercise. BMI
32. PE normal. Hb A1c is 10%. Physician recommends
, NBME 17NBME CBSE REAL EXAM 200 QUESTIONS AND ANSWERS LATES
2025 COMPLETE EXAM
Study online at https://quizlet.com/_hh6z54
initiation of insulin injections. Responds, "I know that
insulin would help control my blood sugar. But a lot of
people in my family have diabetes, and insulin made
them really sick at times. Patient is at which stage of
change?
16. 24yo M with 2-day history of an itchy rash on his arms T-lymphocytes (type IV
and legs. Returned from a camping trip in the woods HS)
5 days ago. PE shows edematous, erythematous rash
with linear vesicles. Cause is activation of which cell
types?
17. 70yo M from china with poorly differentiated mono- EBV
clonal carcinoma of the nasopharynx. DNA probes of
neoplastic cells are most likely to detect genome of
which virus?
18. 24yo M with hx of IVDA could not be aroused. Friend = 200 (0.3) =60
reports that the patient injected himself with a drug 3 half-lives = 120, 240, 480
6 hours ago. Labs show drug concentration of 0.3.
Assuming first-order one-compartment kinetics, has
a half-life of 2 hours, and a volume of distribution of
200 L in this patient. What is quantity of drug (in mg)
injected?
19. Compound is taken up by bacterial cells. No energy is Carrier-mediated diffu-
necessary for uptake, and the compound is not con- sion
centrated in the cell. Which describes this mechanism
of transport?
20. Newborn has male genital ducts but female external Scrotum
genitalia. Cytogenetic analysis shows a 46,XY kary-
2025 COMPLETE EXAM
Study online at https://quizlet.com/_hh6z54
1. 70yo M dies in a motor vehicle collision. Was undergo- Tubular adenoma or vil-
ing evaluation for occult blood in the stool. Photo of lous polyp. GI blood loss
transverse colon shown. Dx? suggests a risk for malig-
nancy
2. 38yo M truck driver with 1-week hx of watery, itchy Loratadine--> less sedat-
eyes and a runny nose. Physical shows inflamed nasal ing antihistamine
mucosa. No congestion in lower lung. Pharmacother-
apy?
3. 16yo girl with 3-day hx of fever, nonproductive cough, IgM (mono and my-
and fatigue. T 38.3, P 88/min, BP 102-70. PE shows coplasma)
pale conjunctivae. CXR shows bilateral interstitial infil-
trates. Blood spontaenously agglutinates while await-
ing transport to the laboratory. Antibody isotypes
causing agglutination?
4. 24yo M with small tender blisters on his penis 3 days HSV-2
after unprotected sex. Photograph shown. Causal
agent?
5. 42yo F with 3-year hx of an intermittent facial rash, in- Rosacea
cluding the forehead, eyelids, nose, and cheeks. Rash
seems to be getting worse since she moved from
New York to Florida last year. Spicy foods precipitate
a flushing reaction that seems to exacerbate the rash.
PE shows erythema over the nose and cheeks, with
scattered telangiectasias and a few papules. Dx?
6. 53yo M returned from Africa, has fever, headache, Malaria
and abdominal discomfort. Received appropriate vac-
, NBME 17NBME CBSE REAL EXAM 200 QUESTIONS AND ANSWERS LATES
2025 COMPLETE EXAM
Study online at https://quizlet.com/_hh6z54
cinations prior to the trip. T 39.4C. A wright-stained
peripheral smear shown (ring forms in RBCs). Dx?
7. 68yo F with T2DM and hypertension that has been ACE I (Lisinopril)
poorly controlled despite hydrochlorothiazide treat-
ment. BP 150/96, Labs show serum glucose concen-
tration of 130 and proteinuria. In addition to current
Rx, which is most appropriate pharmacotherapy?
8. 66yo M with stage IV colon cancer with 3-day hx of Loperamide
severe diarrhea after receiving chemotherapy with
flourouracil, leucovorin, and irinotecan. Prescribed
opioid antidiarrheal agent with no CNS effects. Which
med?
9. 35yo M in ED with 2-hour hx of sever fatigue and V. Cholerae--> activates AC
dizziness. Had profuse, watery diarrhea for 8 hours
despite a lack of oral intake. Recently returned from
a medical relief trip to a remove village in Honduras.
T 36.7 C, P 122/min, BP 90/50. PE shows dry skin
and decreased capillary refill. Stool for occult blood is
negative; stool is gray and turbid. Gram stain shows
gram-negative, comma-shaped bacteria; no erythro-
cytes of leukocytes. MOA of toxin?
10. 59yo F with gradual onset of lack of muscle control Cerebellum
in her left arm and leg. Sx 1 mo ago after dx with
metastatic breast cancer. PE shows ataxia of left up-
per and lower extremities. Muscle strength, DTR, sen-
sation, proprioception normal. Metastatic tumor in
which location?
, NBME 17NBME CBSE REAL EXAM 200 QUESTIONS AND ANSWERS LATES
2025 COMPLETE EXAM
Study online at https://quizlet.com/_hh6z54
11. Newborn delivered at 38 weeks' gestation weighs Congenital CMV infection
1800 g. PE shows petechial rash, microcephaly, and
hepatosplenomegaly. Serologic test for CMV: IgG + in
mother, + in newborn; IGM - in mother, + in newborn.
Explanation?
12. Female newborn is delivered at 38 weeks' gestation. 15-40; neutral tube closes
Apgar 8 and 8 at 1/5 min. PE shows a bulging, flu- at about 4 weeks
od0filled mass approximately 5 cm in diameter in
the midline over the lumbosacral region. No sponta-
neous movements of the lower extremities. Abnor-
mality most likely occurred because of abnormal de-
velopment during which periods of postconception (in
days)?
13. 64yo M in ED 3 hours after SOB with exertion and ex- Torsades de pointes
treme fatigue. Has ischemic heart disease. P 125/min,
BP 105/60. ECG shows atrial fibrillation. Intravenous
ibutilide is administered. Ten minutes later, ECG shows
normal sinus rhythm. Risk for which drug effect in the
next 6 hours?
14. 65yo F with 20-year hx of osteoarthritis of the hands L3 to L4
now has pain radiating down the distal anterior thigh,
knee, medial leg, and food. Bony outgrowth of ver-
tebrae compressing one of the spinal nerves is sus-
pected. Nerve root in which intervertebral foramina is
effected?
15. 38yo M with 3-year hx of T2DM. Taking an oral antihy- Contemplation
perglycemic agent, he has tried diet and exercise. BMI
32. PE normal. Hb A1c is 10%. Physician recommends
, NBME 17NBME CBSE REAL EXAM 200 QUESTIONS AND ANSWERS LATES
2025 COMPLETE EXAM
Study online at https://quizlet.com/_hh6z54
initiation of insulin injections. Responds, "I know that
insulin would help control my blood sugar. But a lot of
people in my family have diabetes, and insulin made
them really sick at times. Patient is at which stage of
change?
16. 24yo M with 2-day history of an itchy rash on his arms T-lymphocytes (type IV
and legs. Returned from a camping trip in the woods HS)
5 days ago. PE shows edematous, erythematous rash
with linear vesicles. Cause is activation of which cell
types?
17. 70yo M from china with poorly differentiated mono- EBV
clonal carcinoma of the nasopharynx. DNA probes of
neoplastic cells are most likely to detect genome of
which virus?
18. 24yo M with hx of IVDA could not be aroused. Friend = 200 (0.3) =60
reports that the patient injected himself with a drug 3 half-lives = 120, 240, 480
6 hours ago. Labs show drug concentration of 0.3.
Assuming first-order one-compartment kinetics, has
a half-life of 2 hours, and a volume of distribution of
200 L in this patient. What is quantity of drug (in mg)
injected?
19. Compound is taken up by bacterial cells. No energy is Carrier-mediated diffu-
necessary for uptake, and the compound is not con- sion
centrated in the cell. Which describes this mechanism
of transport?
20. Newborn has male genital ducts but female external Scrotum
genitalia. Cytogenetic analysis shows a 46,XY kary-
