TEST BANK q
Introduction to Genetic Analysis
q q q
Anthony qJ.F. qGriffiths, qJohn qDoebley, qCatherine qPeichel, qand qDavid qA. qWassarman
12th Edition
q
,Table of Contents
q q
Chapter q01 qThe qGenetics qRevolution 1
Chapter q02 qSingle qGene qInheritance 6
Chapter q03 qIndependent qAssortment qof qGenes 26
Chapter q04 qMapping qEukaryote qChromosomes qby qRecombination 43
Chapter q05 qGene qInteraction 63
Chapter q06 qThe qGenetics qof qBacteria qand qTheir qViruses 84
Chapter q07 qDNA qStructure qand qReplication 104
Chapter q08 qRNA qTranscription qProcessing qand qDecay 117
Chapter q09 qProteins qand qTheir qSynthesis 130
Chapter q10 qGene qIsolation qand qManipulation 141
Chapter q11 qRegulation qof qGene qExpression qin qBacteria qand qTheir qViruses 160
Chapter q12 qRegulation qof qGene qExpression qin qEukaryotes 175
Chapter q13 qThe qGenetic qControl qof qDevelopment 184
Chapter q14 qGenomes qand qGenomics 192
Chapter q15 qDNA qDamage qRepair qand qRecombination 197
Chapter q16 qThe qDynamic qGenome qTransposable qElements 216
Chapter q17 qLarge qScale qChromosomal qChanges 225
Chapter q18 qPopulation qGenetics 243
Chapter q19 qThe qInheritance qof qComplex qTraits 258
Chapter q20 qEvolution qof qGenes qand qTraits 270
, Test qBank q- qIntroduction qto qGenetic qAnalysis, q12th qEdition q(Griffiths, q2021)
Chapter q01: qThe qGenetics qRevolution
1. The qearly q1900s qwas qan qimportant qperiod qfor qgenetics qdue qto qwhich qof qthe qfollowing qmajor qevents?
a. the qrediscovery qof qGregor qMendel's qscientific qfindings
b. Watson qand qCrick qsolving qthe qstructure qof qDNA
c. Walter qSutton qand qTheodore qBoveri qhypothesizing qthat qchromosomes qare qthe qhereditary qelements
d. the qrediscovery qof qGregor qMendel's qscientific qfindings qand qWalter qSutton qand qTheodore
qBoveri qhypothesizing qthat qchromosomes qare qthe qhereditary qelements
e. All qof qthe qanswer qoptions qare qcorrect.
ANSWER: q e
2. A qsample qof qnormal qdouble-stranded qDNA qwas qfound qto qhave qa qguanine qcontent qof q18%. qWhat qis qthe
qexpected qproportion qof qadenine?
a. 9%
b. 32%
c. 36%
d. 68%
e. 82%
ANSWER: q b
3. In qone qstrand qof qDNA, qthe qnucleotide qsequence qis q5'-ATGC-3'. qThe qcomplementary qsequence qin qthe
qother qstrand qmust qbe
a. 3'-ATGC-5'.
b. 3'-TACG-5'.
c. 5'-ATCG-3'.
d. 5'-CGTA-3'.
e. 5'-TACG-3'.
ANSWER: q b
4. How qmany qdifferent qDNA qmolecules qthat qare qeight-nucleotide-pairs qlong qare qtheoretically qpossible?
a. 24
b. 32
c. 64
d. 256
e. 65,536
ANSWER: q e
5. Which qof qthe qfollowing qis/are qTRUE qabout qgenes?
a. Genes qare qlocated qon qchromosomes.
b. Genes qcome qin qvariants qknown qas qalleles.
c. Genes qusually qencode qprotein qproducts.
d. All qof qthe qanswer qoptions qare qcorrect.
e. None qof qthe qanswer qoptions qis qcorrect.
ANSWER: q d
1 | qP qa qg qe
, Test qBank q- qIntroduction qto qGenetic qAnalysis, q12th qEdition q(Griffiths, q2021)
6. Wild qcats q(Felis qsilvestris) qand qcommon qmice q(Mus qmusculus) qare qdiploid. qIn qwild qcats, q2n q= q38,
qwhile qin qcommon qmice, q2n q= q40. qBased qon qthis qinformation, qwe qcan qconclude qthat qwild-cat qcells qhave
a. less qDNA qthan qcommon-mouse qcells.
b. smaller qgenomes qthan qcommon-mouse qcells.
c. fewer qDNA qmolecules qthan qcommon-mouse qcells.
d. fewer qgenes qthan qcommon-mouse qcells.
e. fewer qsets qof qchromosomes qthan qcommon-mouse qcells.
ANSWER: q c
7. Which qof qthe qfollowing qis qa qcomponent qof qDNA?
a. alanine
b. arginine
c. cysteine
d. guanine
e. tyrosine
ANSWER: q d
8. Which qof qthe qfollowing qis/are qTRUE qof qthe qDNA qstructure qsolved qby qWatson qand qCrick?
a. It qis qa qdouble-helical qstructure.
b. Sugar–phosphate qbackbone qis qalways qtoward qthe qoutside qof qthe qDNA.
c. There qare qtwo qhydrogen qbonds qbetween qA qand qT qand qthree qhydrogen qbonds qbetween qC qand qG.
d. There qare qfour qtypes qof qnitrogenous qbases.
e. All qof qthe qanswer qoptions qare qcorrect.
ANSWER: q e
9. Which qof qthe qfollowing qis qa qCORRECT qrepresentation qof qthe qcentral qdogma?
a. RNA q→ qDNA q→ qprotein
b. protein q→ qDNA q→ qRNA
c. DNA q→ qRNA q→ qprotein
d. DNA q→ qprotein q→ qDNA
e. None qof qthe qanswer qoptions qis qcorrect.
ANSWER: q c
10. You qhave qcome qacross qa qdog q(named qCindy) qthat qdoes qnot qhave qa qtail. qInterestingly, qall qthe qpuppies
qproduced qby qthis qdog qdon't qhave qa qtail. qIf qthe qlack qof qtail qis qcaused qby qa qgenetic qmutation, qwhere qhas qthis
qmutation qmost qlikely qtaken qplace?
a. in qCindy's qgametes
b. in qthe qcells qthat qshould qnormally qhave qgiven qrise qto qCindy's qtail
c. in qthe qcells qthat qshould qnormally qhave qgiven qrise qto qCindy's qand qher qpuppies' qtails
d. in qall qof qCindy's qcells q(including qher qgametes)
e. in qa qgamete qof qone qof qCindy's qparents
ANSWER: q a
11. Which qof qthe qfollowing qfeatures qmakes qa qspecies qsuitable qas qa qmodel qorganism?
2 | qP qa qg qe
Introduction to Genetic Analysis
q q q
Anthony qJ.F. qGriffiths, qJohn qDoebley, qCatherine qPeichel, qand qDavid qA. qWassarman
12th Edition
q
,Table of Contents
q q
Chapter q01 qThe qGenetics qRevolution 1
Chapter q02 qSingle qGene qInheritance 6
Chapter q03 qIndependent qAssortment qof qGenes 26
Chapter q04 qMapping qEukaryote qChromosomes qby qRecombination 43
Chapter q05 qGene qInteraction 63
Chapter q06 qThe qGenetics qof qBacteria qand qTheir qViruses 84
Chapter q07 qDNA qStructure qand qReplication 104
Chapter q08 qRNA qTranscription qProcessing qand qDecay 117
Chapter q09 qProteins qand qTheir qSynthesis 130
Chapter q10 qGene qIsolation qand qManipulation 141
Chapter q11 qRegulation qof qGene qExpression qin qBacteria qand qTheir qViruses 160
Chapter q12 qRegulation qof qGene qExpression qin qEukaryotes 175
Chapter q13 qThe qGenetic qControl qof qDevelopment 184
Chapter q14 qGenomes qand qGenomics 192
Chapter q15 qDNA qDamage qRepair qand qRecombination 197
Chapter q16 qThe qDynamic qGenome qTransposable qElements 216
Chapter q17 qLarge qScale qChromosomal qChanges 225
Chapter q18 qPopulation qGenetics 243
Chapter q19 qThe qInheritance qof qComplex qTraits 258
Chapter q20 qEvolution qof qGenes qand qTraits 270
, Test qBank q- qIntroduction qto qGenetic qAnalysis, q12th qEdition q(Griffiths, q2021)
Chapter q01: qThe qGenetics qRevolution
1. The qearly q1900s qwas qan qimportant qperiod qfor qgenetics qdue qto qwhich qof qthe qfollowing qmajor qevents?
a. the qrediscovery qof qGregor qMendel's qscientific qfindings
b. Watson qand qCrick qsolving qthe qstructure qof qDNA
c. Walter qSutton qand qTheodore qBoveri qhypothesizing qthat qchromosomes qare qthe qhereditary qelements
d. the qrediscovery qof qGregor qMendel's qscientific qfindings qand qWalter qSutton qand qTheodore
qBoveri qhypothesizing qthat qchromosomes qare qthe qhereditary qelements
e. All qof qthe qanswer qoptions qare qcorrect.
ANSWER: q e
2. A qsample qof qnormal qdouble-stranded qDNA qwas qfound qto qhave qa qguanine qcontent qof q18%. qWhat qis qthe
qexpected qproportion qof qadenine?
a. 9%
b. 32%
c. 36%
d. 68%
e. 82%
ANSWER: q b
3. In qone qstrand qof qDNA, qthe qnucleotide qsequence qis q5'-ATGC-3'. qThe qcomplementary qsequence qin qthe
qother qstrand qmust qbe
a. 3'-ATGC-5'.
b. 3'-TACG-5'.
c. 5'-ATCG-3'.
d. 5'-CGTA-3'.
e. 5'-TACG-3'.
ANSWER: q b
4. How qmany qdifferent qDNA qmolecules qthat qare qeight-nucleotide-pairs qlong qare qtheoretically qpossible?
a. 24
b. 32
c. 64
d. 256
e. 65,536
ANSWER: q e
5. Which qof qthe qfollowing qis/are qTRUE qabout qgenes?
a. Genes qare qlocated qon qchromosomes.
b. Genes qcome qin qvariants qknown qas qalleles.
c. Genes qusually qencode qprotein qproducts.
d. All qof qthe qanswer qoptions qare qcorrect.
e. None qof qthe qanswer qoptions qis qcorrect.
ANSWER: q d
1 | qP qa qg qe
, Test qBank q- qIntroduction qto qGenetic qAnalysis, q12th qEdition q(Griffiths, q2021)
6. Wild qcats q(Felis qsilvestris) qand qcommon qmice q(Mus qmusculus) qare qdiploid. qIn qwild qcats, q2n q= q38,
qwhile qin qcommon qmice, q2n q= q40. qBased qon qthis qinformation, qwe qcan qconclude qthat qwild-cat qcells qhave
a. less qDNA qthan qcommon-mouse qcells.
b. smaller qgenomes qthan qcommon-mouse qcells.
c. fewer qDNA qmolecules qthan qcommon-mouse qcells.
d. fewer qgenes qthan qcommon-mouse qcells.
e. fewer qsets qof qchromosomes qthan qcommon-mouse qcells.
ANSWER: q c
7. Which qof qthe qfollowing qis qa qcomponent qof qDNA?
a. alanine
b. arginine
c. cysteine
d. guanine
e. tyrosine
ANSWER: q d
8. Which qof qthe qfollowing qis/are qTRUE qof qthe qDNA qstructure qsolved qby qWatson qand qCrick?
a. It qis qa qdouble-helical qstructure.
b. Sugar–phosphate qbackbone qis qalways qtoward qthe qoutside qof qthe qDNA.
c. There qare qtwo qhydrogen qbonds qbetween qA qand qT qand qthree qhydrogen qbonds qbetween qC qand qG.
d. There qare qfour qtypes qof qnitrogenous qbases.
e. All qof qthe qanswer qoptions qare qcorrect.
ANSWER: q e
9. Which qof qthe qfollowing qis qa qCORRECT qrepresentation qof qthe qcentral qdogma?
a. RNA q→ qDNA q→ qprotein
b. protein q→ qDNA q→ qRNA
c. DNA q→ qRNA q→ qprotein
d. DNA q→ qprotein q→ qDNA
e. None qof qthe qanswer qoptions qis qcorrect.
ANSWER: q c
10. You qhave qcome qacross qa qdog q(named qCindy) qthat qdoes qnot qhave qa qtail. qInterestingly, qall qthe qpuppies
qproduced qby qthis qdog qdon't qhave qa qtail. qIf qthe qlack qof qtail qis qcaused qby qa qgenetic qmutation, qwhere qhas qthis
qmutation qmost qlikely qtaken qplace?
a. in qCindy's qgametes
b. in qthe qcells qthat qshould qnormally qhave qgiven qrise qto qCindy's qtail
c. in qthe qcells qthat qshould qnormally qhave qgiven qrise qto qCindy's qand qher qpuppies' qtails
d. in qall qof qCindy's qcells q(including qher qgametes)
e. in qa qgamete qof qone qof qCindy's qparents
ANSWER: q a
11. Which qof qthe qfollowing qfeatures qmakes qa qspecies qsuitable qas qa qmodel qorganism?
2 | qP qa qg qe
