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What causes the body to increase the excretion of a drug through the renal system?

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Test Bank Pharmacotherapeutics for Advanced Practice Nurse Prescribers 6th Edition Questions and approved answers What causes the body to increase the excretion of a drug through the renal system? (Answer)- Unbinding a nonvolatile drug from plasma proteins. What is "steady state"? (Answer)- When the amount of the drug in the body remains constant When two pain medications are given together to treat pain, what kind of drug-to-drug interaction occurs? (Answer)- Additive Actions taken to reduce drug—drug interaction problems include all of the following EXCEPT: 1) Reducing the dosage of one of the drugs 2) Scheduling their administration at different times 3) Prescribing a third drug to counteract the adverse reaction of the combination 4) Reducing the dosage of both drugs (Answer)- Prescribing a third drug to counteract the adverse reaction of the combination What is the period of time called that it takes for a drug too decreased by 50% in the body? (Answer)- Half Life

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Pharmacotherapeutics for Advanced Practice Nurse Prescribers




Test Bank
Pharmacotherapeutics for Advanced Practice Nurse Prescribers
6th Edition
Questions and approved answers




@ pg. 1

, Pharmacotherapeutics for Advanced Practice Nurse Prescribers




What causes the body to increase the excretion of a drug through the renal system?
(Answer)- ✔✔✔Unbinding a nonvolatile drug from plasma proteins.


What is "steady state"?
(Answer)- ✔✔✔When the amount of the drug in the body remains constant


When two pain medications are given together to treat pain, what kind of drug-to-
drug interaction occurs?
(Answer)- ✔✔✔Additive


Actions taken to reduce drug—drug interaction problems include all of the
following EXCEPT:
1) Reducing the dosage of one of the drugs
2) Scheduling their administration at different times
3) Prescribing a third drug to counteract the adverse reaction of the combination
4) Reducing the dosage of both drugs
(Answer)- ✔✔✔Prescribing a third drug to counteract the adverse reaction of the
combination




What is the period of time called that it takes for a drug too decreased by 50% in
the body?
(Answer)- ✔✔✔Half Life


Drug antagonism is best defined as an effect of a drug that:

@ pg. 2

, Pharmacotherapeutics for Advanced Practice Nurse Prescribers


1. Leads to major physiological and psychological dependence
2. Is modified by the concurrent administration of another drug
3. Cannot be metabolized before another dose is administered
4. Leads to a decreased physiological response when combined with another drug
(Answer)- ✔✔✔Is modified by the concurrent administration of another drug


What happens when a drug antagonist is given regularly?
(Answer)- ✔✔✔Down regulated the number of specific receptors


What should be included in the education fo those who are prescribed oral enteric
coated tables (Answer)- ✔✔✔To achieve best effect, take the tablet with at least
8 oz of fluids


What is the main reason for not crushing a sustained-released capsule?
(Answer)- ✔✔✔It can cause toxicity


What medication in the follow is mostly absorbed in the intestines rather than the
stomach?


1) Sodium bicarb
2) Ascorbic acid
3) Salicylic acid
4) Glucose
(Answer)- ✔✔✔Sodium Bicarb


Which of the following variables is a factor in drug absorption?


@ pg. 3

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