Chapter 4 2025
A client asks a nurse how medications are distributed within the body. What among the below would be the
nurse's response?
- "The blood-brain barrier inhibits rapid crossing of all medications."
- "Body organs with high levels of blood flow are more difficult organs to which to deliver
drugs."
- "Medications that are lipid-soluble are more completely distributed."
- "Drug-protein complexes must form prior to crossing capillary membranes." - ans"Medications that are lipid-
soluble are more completely distributed."
A client asks a nurse why a large dose of a drug was administered first followed by a lower dose of the same
drug later. What is the nurse's best response?
- Prevent a toxic concentration of the drug
- Achieve a therapeutic dose more quickly
- Decrease the side effects of this drug
- Increase the absorption rate of this drug - ansAchieve a therapeutic dose more quickly
A client asks a nurse why he experiences a metallic taste after taking certain medications. The nurse explains
that some medications are secreted by glandular activity. The nurse would identify which substances as
examples of this excretion?
Note: Credit will be given only if all correct choices and no incorrect choices are selected. Select all that apply.
Saliva
Sweat
Breast milk
Urine
Feces - ansSaliva
Sweat
, Breast milk
A client comes to the emergency department following an overdose of aspirin, which is an acidic drug. The
nurse should anticipate administering which of the following?
- Intravenous fluids to flush the kidneys
- Ammonium chloride to increase metabolism in the liver
- Sodium bicarbonate to alter the client's serum pH
- Intravenous proteins to bind the aspirin - ansSodium bicarbonate to alter the client's serum pH
A client is admitted to the hospital in chronic renal failure and several drugs are prescribed. What best
describes the nurse's assessment of this client?
- The client's liver may compensate for renal failure so the drugs may be effective.
- The client may have drug toxicity from all the drugs.
- The client may have drug toxicity only if the drugs are excreted by the kidneys.
- The client may have decreased effectiveness of the drugs. - ansThe client may have drug toxicity from all the
drugs.
A client is receiving a drug that is excreted in the bile. What will the best nursing assessment of the effect of
this drug on the patient include?
- The effect of the drug will be a prolonged action.
- The effect of the drug will be increased side effects.
- The effect of the drug will be decreased side effects.
- The effect of the drug will be decreased. - ansThe effect of the drug will be a prolonged action.
A client is receiving lithium (Eskalith) and asks the nurse why their blood has to be drawn so often. What is the
best response by the nurse?
- "To detect side effects before they become a problem."
- "To be sure the medication is working properly."
- "To determine if your body is responding as it should."
A client asks a nurse how medications are distributed within the body. What among the below would be the
nurse's response?
- "The blood-brain barrier inhibits rapid crossing of all medications."
- "Body organs with high levels of blood flow are more difficult organs to which to deliver
drugs."
- "Medications that are lipid-soluble are more completely distributed."
- "Drug-protein complexes must form prior to crossing capillary membranes." - ans"Medications that are lipid-
soluble are more completely distributed."
A client asks a nurse why a large dose of a drug was administered first followed by a lower dose of the same
drug later. What is the nurse's best response?
- Prevent a toxic concentration of the drug
- Achieve a therapeutic dose more quickly
- Decrease the side effects of this drug
- Increase the absorption rate of this drug - ansAchieve a therapeutic dose more quickly
A client asks a nurse why he experiences a metallic taste after taking certain medications. The nurse explains
that some medications are secreted by glandular activity. The nurse would identify which substances as
examples of this excretion?
Note: Credit will be given only if all correct choices and no incorrect choices are selected. Select all that apply.
Saliva
Sweat
Breast milk
Urine
Feces - ansSaliva
Sweat
, Breast milk
A client comes to the emergency department following an overdose of aspirin, which is an acidic drug. The
nurse should anticipate administering which of the following?
- Intravenous fluids to flush the kidneys
- Ammonium chloride to increase metabolism in the liver
- Sodium bicarbonate to alter the client's serum pH
- Intravenous proteins to bind the aspirin - ansSodium bicarbonate to alter the client's serum pH
A client is admitted to the hospital in chronic renal failure and several drugs are prescribed. What best
describes the nurse's assessment of this client?
- The client's liver may compensate for renal failure so the drugs may be effective.
- The client may have drug toxicity from all the drugs.
- The client may have drug toxicity only if the drugs are excreted by the kidneys.
- The client may have decreased effectiveness of the drugs. - ansThe client may have drug toxicity from all the
drugs.
A client is receiving a drug that is excreted in the bile. What will the best nursing assessment of the effect of
this drug on the patient include?
- The effect of the drug will be a prolonged action.
- The effect of the drug will be increased side effects.
- The effect of the drug will be decreased side effects.
- The effect of the drug will be decreased. - ansThe effect of the drug will be a prolonged action.
A client is receiving lithium (Eskalith) and asks the nurse why their blood has to be drawn so often. What is the
best response by the nurse?
- "To detect side effects before they become a problem."
- "To be sure the medication is working properly."
- "To determine if your body is responding as it should."
