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Summary GCSE Biology Notes: DNA and Genetics Aqa.

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GCSE Biology Notes: DNA and Genetics Ace your GCSE Biology exams with these clear, concise notes on DNA and Genetics. Key topics include: DNA structure, chromosomes, genes, and protein synthesis Genetic mutations, reproduction (sexual and asexual), mitosis & meiosis Diagrams and examples for better understanding Exam-focused summaries to help you revise efficiently Perfect for quick revision or mastering complex concepts. Get exam-ready with these easy-to-follow, comprehensive notes!

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Biology es




stands
fordeoxyribonucleicacid isthechemicalthatmakesupallgeneticmaterialinacell also

containscodedinformationwhichareinstructions
fororgansims tomakethemwork DNA isfoundinlongstructures
calledchromosomes Chromosomes
normallycomeinpairs


Titan
sayof containslayers
nucleus
arm ofDNA
Genes

Geneisasmallsection DNAEach codes
of
gene fortellsthecellstomake aparticlarsequenceofaminoacidswhich
form a specificprotien Only20aminoacidsare usedtomakeupthousandsofdifferentprotiensGenestellcellswh
Ordertoputtheaminoacidstogether DNAalsodetermineswhatprotiensthecellproduces determineswhattype cell
of

Genomes

Genomemeansthe
entiresetofgeneticmaterialin anorganismScientistshaveworkedoutthecompletehumangenome

hisisimportantbecause
identifygenesthatarelinkedtodiseases
allowsscientiststo

which linkedtoinheriteddiseasesthelptounderstandthembetter helptodeveloptreatments
nowing genes are
Canalsolookatgenomestotracemigration certainpopulations peoplearoundtheworldworkoutwhennewpopulat
of of
Splitoffastherearetinydifferencesingenomewhenpeoplemovedaway

Structure
of
tisapolymerandhasadoublehelixstructuretismadeupofnucleotides achnucleotidesconsistsofasugaraphosphate
andabase_baseEitherATCorG joinstoeachsugarteachbaselinkstoabaseontheoppositestrandinthehelixA
andCpairswithG complementarybasepairingThe
alwayspairswithT order basesinagenedecidesthe
of order amino
of
acidsinaprotie

achaminoacidiscoded
forbyasequenceofthreebases theaminoacidsarejoinedtomakevariousprotiensThereareparts
ofDNAthatdon'tcodeforprotiensThesecan switchgenesonofftocontrolifa geneisusedtomakea protien

, Trotiens
Phospate aremadeinthecellcytoplasmon ribosomes 0make

thecodeintheDNASothecellneedstog
protiensribosomesuse

nucleotide thecodefromtheDNAtotheRibosomes hisisdone
using
a moleculecalledMRNA whichismade code
bycopyingthe fro
INA hem isamessengerbetweentheDNAandthe
Ribosome hecorrectaminoacidsarethenbroughttothe
Ribosomesinthecorrectorder
bycarriermolecules

Trotein unctions

chemicalreactions in
nzymes actasbiologicalcatalyststospeedup body
ormones Usedto aroundthebody
carrymessages
Structural Proteins are
physicallystronge gcollagen strengthensconnectivetissues




u a ions
mutationis a randomchangein anorganism'sDNA can
beinherited
mutationschangethesequence
oftheDNAbasesin a genewhichproducesa geneticvariantthissometimes
protienthatit
eadstochangesinthe codes
forMostmutationsdonthaveaneffectontheprotienhow
somedohaveanaffectandmeansthemutationwillcode
foranalteredprotien changeitsshapewhich
Whichaffectits
abilitytofunction hiscouldmaketheprotienslosetheirstrength or iftheyareenzymeschang
itsactivesite

utations
ypes of
insertions iswhereanewbaseisinsertedintotheDNAbasesequencewhereitshouldn'tbeSinceeachbaseseque

foraspecificaminoacid Ininsertioncanchangetheaminoacidstheycodefor canchangemorethan 1
Codes

aminoacidastheyhaveaknockon effect ontheotherbases inthesequence

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