LEARNING MATERIALS
Subject: Biology / Human Physiology / Medicine
Unit 1: Introduction to Cell Biology / Cell Biology for Medicine
Topic 1: Introduction to Cell Biology / Cell Biology for Medicine
Level: 3
Essential reading:
The essential textbook for this topic is Tortora, G.J., and Grabowski,
S.R., 2002. Principles of Anatomy and Physiology. 10th ed. London:
John Wiley & Sons. ISBN no: 9780471224723
Recommended reading:
Recommended reading for this topic is listed in the back pages of
these learning materials.
Further resources:
Further resources to deepen your learning on specific aspects of this
topic are listed throughout these learning materials.
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, Subject: Biology / Human Physiology / Medicine
Unit 1: Introduction to Cell Biology / Cell Biology for Medicine
Topic 1: Introduction to Cell Biology / Cell Biology for Medicine
Level: 3
LEARNING MATERIALS
Contents
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Introduction .............................................................................................3
1. Microscopes .....................................................................................5
1.1 Light microscopes .......................................................................................5
1.2 Electron microscopes ..................................................................................6
2. Cell structure....................................................................................7
2.1 Prokaryotic cells ..........................................................................................7
2.1.1 Nucleoid.........................................................................................8
2.1.2 Plasmids ........................................................................................8
2.1.3 Ribosomes ....................................................................................8
2.1.4 Pili and flagellum ...........................................................................9
2.2 Eukaryotic cells: Animals ............................................................................9
2.2.1 Nucleus........................................................................................10
2.2.2 Endoplasmic reticulum ................................................................10
2.2.3 Golgi apparatus ...........................................................................11
2.2.4 Mitochondria ................................................................................11
2.2.5 Cytoskeleton................................................................................12
2.3 Eukaryotic cells: Plants .............................................................................13
2.3.1 Central vacuole ...........................................................................13
2.3.2 Cell wall .......................................................................................13
2.3.3 Chloroplasts ................................................................................14
2.4 Specialised eukaryotic cells ......................................................................14
2.4.1 Red blood cells ............................................................................14
2.4.2 Spermatozoa ...............................................................................14
3. Membrane structure and function .................................................. 16
3.1 Fluid mosaic model ...................................................................................16
3.1.1 The phospholipid bilayer .............................................................17
3.1.2 Proteins .......................................................................................17
3.1.3 Carbohydrates .............................................................................18
3.1.4 Cholesterol ..................................................................................18
3.2 Passive transport.......................................................................................18
3.2.1 Simple diffusion ...........................................................................18
3.2.2 Osmosis.......................................................................................19
3.2.3 Facilitated diffusion .....................................................................19
© DistanceLearningCentre.com, 2022
, Subject: Biology / Human Physiology / Medicine
Unit 1: Introduction to Cell Biology / Cell Biology for Medicine
Topic 1: Introduction to Cell Biology / Cell Biology for Medicine
Level: 3
LEARNING MATERIALS
3.3 Active transport..........................................................................................20
3.4 Bulk transport ............................................................................................21
3.4.1 Endocytosis .................................................................................21
3.4.2 Exocytosis ...................................................................................21
4. Cell division ................................................................................... 23
4.1 Mitosis........................................................................................................23
4.1.1 Prophase .....................................................................................24
4.1.2 Prometaphase .............................................................................25
4.1.3 Metaphase...................................................................................25
4.1.4 Anaphase ....................................................................................25
4.1.5 Telophase....................................................................................25
4.1.6 Cytokinesis ..................................................................................25
4.2 Meiosis.......................................................................................................26
4.2.1 Crossing over ..............................................................................26
4.2.2 Independent assortment .............................................................27
5. Necrosis and apoptosis ................................................................. 29
5.1 Necrosis .....................................................................................................29
5.2 Apoptosis ...................................................................................................29
Appendix ................................................................................................ 31
Recommended reading .......................................................................... 34
Resources .............................................................................................. 34
Sources and credits ............................................................................... 34
Image credits ......................................................................................................34
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