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Exam (elaborations)

Bms Test 1

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Exam of 19 pages for the course Prevention and Rehab at Prevention and Rehab (BMS TEST 1)

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BMS TEST 1
Anion gap normal range
12-16 mEq/L


Anion gap
Sodium + potassium / bicarb + chloride




Large anion gap indicates
Renal failure and lactic acidosis


Osmol gap normal
0


Osmol gap
Measured - calculated


Osmol gap equation
2 x Na + glucose/18 + BUN/3


Osmol gap greater than 3 indicates
Alcohol presence


Large Vd
Vd greater than 5


Large Vd distributed
In tissues

,Drugs with large Vd
Antidepressants, antipsychotic, anti-malarials, opioids, Verapmil


Small Vd is
Vd less than 1


Small Vd is distributed
In blood & ECF


Small Vd drugs
Salicylate, acetaminophen, ethanol, lithium, phenytoin


Methanol and ethylene glycol antidote
Ethanol, fomepizole


Benzo antidote
Flumanezil


Acetaminophen toxicity in adults
7g


Acetaminophen max adult dose
4g


Acetaminophen symptoms
Asymptomatic, mild GI upset, liver failure, kidney injury

, Acetaminophen antidote
N-acetylcysteine


N-acetylcysteine
Acts as glutathione
Binds to toxic metabolite


Cyanide antidote
Cyanokit and kit of nitrate & sodium thiosulfate


Cyanide MOA
Bind to cytochrome oxidase
Inhibits O2 binding


Cyanide symptoms
SOB, agitation seizures coma


Snake venom antidote
Crofab/anti venom


Snake venom symptoms
Vomiting, metallic taste in mouth, shock, pain, swelling, fang marks


Neuronopathy
Death of neuron


Drugs that cause neuronopathy
CO, EtOH, Pb, methyl mercury, carbon tetra, ROS

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