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Summary Topic 4 - genetic information - AQA A-level biology notes

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June 7, 2024
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Summary

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DNA Genes and chromosomes

prokaryotic eukaryoticDNA



eukaryotic Dna is LONG LINEAR Associated w Histones


prokaryotic Dna is shorter circular not associated w proteins

prokaryotic Dna has nointrons
prokaryotic Dna also contained in plasmids


mitochondria chloroplast put is same as prokaryotic



In a eukaryotic cell


DNA associatedhistones fold toform a chromosome

Homologouspair 2 chromosomes with the same genes at the same loci but mayhave
differentalleles of samegene Imaternal I paternal

Gene a lengthof DNA that codes for theaminoacidsequence of a polypeptide
functionalRNA rRNA ERNA


Alleles Differentversions of the samegene

Locus position of gene on chromosome



Between genes there can be noncodingmultiplerepeats


Donotcodeforpolypeptide
theyaremultiplerepeatsofbases eg AtatatatAt

,Insidegene someparts code for polypeptide some dont


exons sequence ofbaseswithin a genethat code forAAsequence ofpolypeptide
introns sequence of bases withina gene that donotcode forAAsequence of polypeptide


intranscription premrnasplicedtoremoveintrons
prokaryoticDnahasno introns




Thegeneticcode

triplet 3baseson DNA
codefor I AminoAcid

codon 3bases on mRNA
complementaryto a DNAtriplet
codes for I aminoacid


anticodon 3 tRNAbases complementarytocodon



Universal in all organisms the sametripletcodesfor same aminoacid


Non overlapping each base is onlypartof I tripletandonlyread once

Degenerate There can be more than one tripletcode for an Amino Acid

, DNA Protein Synthesis

genome thecomplete set of genes in a cell

proteome the fullrange of proteins a cell is able to produce



MRNA d
RNAsugarribose DNAdeoxyribose


RNAhasuracilinsteadof thymine

t
Ribose RNAsinglestranded DNAdoublestranded


RNAis a shootermoleculethanDNA



ERNA
singleRNAmolecule with Hbondsbetween complementary bases folding itinto a cloverleaf shape
hasAAbindingsite
has sequence of 3 bases calledanticodon

Differences w me
ERNAshorter
qq.ggg.gg

tRNAcloverleafshaped mRNAstraightmolecule



GO ERNAhasHbonds mRNAdoesnot


tRNAhasanticodon mrnahascodons
vow
anticodon


tRNAhas AminoAcidbindingsite mrnadoesn't
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