Name: Adewale Eletu P3
Assessor name: Michael Hickey
In this assignment, I will be producton and detecton of radiopharmaceutcalss
RADIOPHARMACEUTICALS
Radiopharmaceutcals are a group of pharmaceutcal drugs that have radioisotopes, which can be
used as diagnostc and therapeutc agentss Radiopharmaceutcals emit radiaton themselves, which
is diferent from contrast media; absorb or alter extternal electromagnetsm or ultrasounds Most
radiopharmaceutcals are combinaton of a radioactve molecule, a radionuclide, that permits
extternal detecton and a biologically actve molecule or drug that acts as a carrier and determines
localizaton and bio distributons
Productoon of Radiohaaraacࡸutcals
Radiopharmaceutcals contain small amounts of radioisotopes that can be produced by irradiatng a
specifc target inside a nuclear research reactor or partcle accelerators, such as cyclotronss hhe
cyclotron is essentally a vacuum chamber in which, by means of a magnetc feld parallel to itself –
which is responsible for defectng ions – and a system that generates an electric feld elementary
partcles can be accelerated to very high energiess hhese partcles will then interact with targets
where nuclear reactons take place that lead to obtaining radioactve isotopes and partcle beams
with the use in medicines Once produced, the radioisotopes are tagged on to certain molecules
based on biological characteristcs, which results in radiopharmaceutcalss
Ahhlicatoon of Radiohaaraacࡸutcals
Radiopharmaceutcals can be used for either diagnostc or therapeutc purposes depending on its
specifc radiaton propertess hhe characteristc of radioactve decay is what makes radioisotopes
useful in their medical applicatons; however, diferent applicatons will take advantage of
radioactve emissions in diferent wayss In this report, I will be discussing the diagnostc and
therapeutc use of radiopharmaceutcalss
Diagonostc ahhlicatoons
In diagnostc imaging, the radiopharmaceutcal is composed of a radioisotope bond to an organic
molecules hhe organic molecule conveys the radioisotope to specifc organs, tssues or cellss
hhe radioisotope is selected for its propertess Radioisotopes emitting penetratng gamma rays are
used for diagnostc imaging where the radiaton has to escape the body before being detected by a
specifc device (SPPECh/PEh cameras).s hypically, the radiaton emited by isotope used for imaging
vanishes completely afer day through radioactve decay and normal body extcretons hhe most
common isotopes for imaging are hc-99m, I- 23, I- 3 , F- 8, etcs
Tࡸcaonࡸtuam99a: hhe most widely used radioisotope in medicine is technetum-99ms hechnetum-
99m is metastable nuclear isomer of technetum-99 and has almost ideal characteristcs for a nuclear
medicine scans hechnetum-99m is used as a radioactve tracer and can be detected in the body by
medical equipment (Sgamma cameras).s It is well suited to the role, because it emits readily
detectable gamma rays with a photon energy of 40 keV and its half-life for gamma emission is 6
hourss Its half-life is long enough to extamine metabolic processes yet short enough to collect data
rapidly and minimise the radiaton dose to the patents hhe same characteristcs make the isotope
suitable only for diagnostc but never therapeutc uses
Assessor name: Michael Hickey
In this assignment, I will be producton and detecton of radiopharmaceutcalss
RADIOPHARMACEUTICALS
Radiopharmaceutcals are a group of pharmaceutcal drugs that have radioisotopes, which can be
used as diagnostc and therapeutc agentss Radiopharmaceutcals emit radiaton themselves, which
is diferent from contrast media; absorb or alter extternal electromagnetsm or ultrasounds Most
radiopharmaceutcals are combinaton of a radioactve molecule, a radionuclide, that permits
extternal detecton and a biologically actve molecule or drug that acts as a carrier and determines
localizaton and bio distributons
Productoon of Radiohaaraacࡸutcals
Radiopharmaceutcals contain small amounts of radioisotopes that can be produced by irradiatng a
specifc target inside a nuclear research reactor or partcle accelerators, such as cyclotronss hhe
cyclotron is essentally a vacuum chamber in which, by means of a magnetc feld parallel to itself –
which is responsible for defectng ions – and a system that generates an electric feld elementary
partcles can be accelerated to very high energiess hhese partcles will then interact with targets
where nuclear reactons take place that lead to obtaining radioactve isotopes and partcle beams
with the use in medicines Once produced, the radioisotopes are tagged on to certain molecules
based on biological characteristcs, which results in radiopharmaceutcalss
Ahhlicatoon of Radiohaaraacࡸutcals
Radiopharmaceutcals can be used for either diagnostc or therapeutc purposes depending on its
specifc radiaton propertess hhe characteristc of radioactve decay is what makes radioisotopes
useful in their medical applicatons; however, diferent applicatons will take advantage of
radioactve emissions in diferent wayss In this report, I will be discussing the diagnostc and
therapeutc use of radiopharmaceutcalss
Diagonostc ahhlicatoons
In diagnostc imaging, the radiopharmaceutcal is composed of a radioisotope bond to an organic
molecules hhe organic molecule conveys the radioisotope to specifc organs, tssues or cellss
hhe radioisotope is selected for its propertess Radioisotopes emitting penetratng gamma rays are
used for diagnostc imaging where the radiaton has to escape the body before being detected by a
specifc device (SPPECh/PEh cameras).s hypically, the radiaton emited by isotope used for imaging
vanishes completely afer day through radioactve decay and normal body extcretons hhe most
common isotopes for imaging are hc-99m, I- 23, I- 3 , F- 8, etcs
Tࡸcaonࡸtuam99a: hhe most widely used radioisotope in medicine is technetum-99ms hechnetum-
99m is metastable nuclear isomer of technetum-99 and has almost ideal characteristcs for a nuclear
medicine scans hechnetum-99m is used as a radioactve tracer and can be detected in the body by
medical equipment (Sgamma cameras).s It is well suited to the role, because it emits readily
detectable gamma rays with a photon energy of 40 keV and its half-life for gamma emission is 6
hourss Its half-life is long enough to extamine metabolic processes yet short enough to collect data
rapidly and minimise the radiaton dose to the patents hhe same characteristcs make the isotope
suitable only for diagnostc but never therapeutc uses
