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Summary AQA ALEVEL BIOLOGICAL NOTES ON HUMORAL REPSONSE

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ALEVEL NOTES ON THE IMMUNITY TOPIC- HUMORAL RESPONSE ADJUSTED TO THE AQA SPECIFICATION AND MADE FROM MARKSCHEMES

Institution
AQA

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Humoral Response
=
-

In the cell-mediated 1 cellular
response ,
the mitotic division of specific T cells form a clone

of the relevant T cells to build their numbers
up .




-
Some of these T cells produce factors that stimulate B cells to divide .




It these B that involved the of humoral
is cells in next phase the immune immunity
>

a re
response : .




,Stages
*.÷÷
of B lymphocyte Response

-5¥

1 The surface of B
antigens an
invading pathogen are taken up by a
complementary cell .




2 The the
pathogen is endocytosed ,
and antigen presented on the plasma membrane .




3 binds to the the B cell colonial selection) ( process
Helper T cells presented antigen ,
activating
at previous )
page .




4 The B cell of
is now activated to divide
by mitosis to
give a clone
plasma cells .




( clonal expansion )


5 antibodies
The cloned plasma cells produce and secrete .
The
antibody is then attached
and them
to
antigens on the pathogen destroys .




B infections
6 cells also develop into
memory
cells . These can respond to future
by the


dividing rapidly developing that produce antibodies
same
pathogen by and into plasma cells .




attach to
on
5
>
antigens and

processedpresentation ft
pathogen
destroy
it

invading antigen
a

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pathogen §
a
, Bad,
rt It
if




} rt
%v antibody
separated
'


I
' 4


cell

plasma

or
antigen
+ § 6
y
I
f IF circulate in blood and





n
,
0 0
tissue fluid in readiness

antibody •

-
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i




lymphocyte
a
cells
I into plasma
B
1 developing
^ ,
that produce
antibodies
(
secondary response)


activated helper
( from
cell-mediated memory
cell
T-cell I
response

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Written in
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