mico
(UNG CANCEr
No
screening programme in UK, Specific Red Flags:
·
can be screened with CT.
but
Haemoptysis
-
Very bad prognosis, 90% 5-year mortality Unexplained Cough
·
-
-
Hoarse voice due to
Investigation: laryngeal
·
n. compression.
-Cervical/supraclaricular
·
First line is XR: -
consolidation lymphadenopathy.
-Pulmonary Nodules Thrombocytosis (platelets)
-
secondary Effusion/collapse
-
·
Gold Standard is CT+ PET scan. Risk Factors:
Bronchoscopy/Biopsy smoking
· -
-
occupation:esp. Asbestos
·
Classification: -
Radiation
-
FH
Non-small cell lung Cancer (NSCLC):
·
includes:Adenocarcinoma, Squamous, large cell.
Mostcommon -80%
·
small cell lung cancer:
Features:in heavier smokers, centrally located, early metastasis.
·
have
most metastasised atpresentation.
Worse than NSCLC.
prognosis
·
Arise from endocrine cells, secrete ACTH/ADH causing Cushing's Syndrome
·
so can
-
I
and /or Hyponatraemia/SIADH
Pleural Mesothelioma:
·
tumour in mesothelium of pleura.
·
Only cause is previous asbestos exposure.
·
treatment:
a
·
NSCLC Treatment:
Surgery be used for
·
can
surgical excition/lobectomy:used for curative intent. micro-metastas is.
For TNM be combined with
stages 1-3.
· ·
can
adjuvant chemo/radiotherapy
Radical Radiation: for curative intent. prolonged survival
radiotherapy for or
used if too frail for
patient surgery. palliation.
·
Palliative Chemo/Radiotherapy:used to relieve symptoms only.
Immunotherapy:monoclonal antibodies targetting EGF Receptor on some NSCLC.
(UNG CANCEr
No
screening programme in UK, Specific Red Flags:
·
can be screened with CT.
but
Haemoptysis
-
Very bad prognosis, 90% 5-year mortality Unexplained Cough
·
-
-
Hoarse voice due to
Investigation: laryngeal
·
n. compression.
-Cervical/supraclaricular
·
First line is XR: -
consolidation lymphadenopathy.
-Pulmonary Nodules Thrombocytosis (platelets)
-
secondary Effusion/collapse
-
·
Gold Standard is CT+ PET scan. Risk Factors:
Bronchoscopy/Biopsy smoking
· -
-
occupation:esp. Asbestos
·
Classification: -
Radiation
-
FH
Non-small cell lung Cancer (NSCLC):
·
includes:Adenocarcinoma, Squamous, large cell.
Mostcommon -80%
·
small cell lung cancer:
Features:in heavier smokers, centrally located, early metastasis.
·
have
most metastasised atpresentation.
Worse than NSCLC.
prognosis
·
Arise from endocrine cells, secrete ACTH/ADH causing Cushing's Syndrome
·
so can
-
I
and /or Hyponatraemia/SIADH
Pleural Mesothelioma:
·
tumour in mesothelium of pleura.
·
Only cause is previous asbestos exposure.
·
treatment:
a
·
NSCLC Treatment:
Surgery be used for
·
can
surgical excition/lobectomy:used for curative intent. micro-metastas is.
For TNM be combined with
stages 1-3.
· ·
can
adjuvant chemo/radiotherapy
Radical Radiation: for curative intent. prolonged survival
radiotherapy for or
used if too frail for
patient surgery. palliation.
·
Palliative Chemo/Radiotherapy:used to relieve symptoms only.
Immunotherapy:monoclonal antibodies targetting EGF Receptor on some NSCLC.
