self-limiting -
Viral
no treatmentrequired, just
Hepatitis supportive.
HAV SEROLOGY
·
Vaccine available for all types exceptHEV.
Chronic Hepatitis B, C, D only.
· =
Acute Hepatitis Symptoms: asymptomatic
·
-
-
Hepatic cause of Jaundice.
organomegaly
-
Liver Failure.
-
Fever, vomiting. Risk Factors: contaminated
A
- -
nausea,
-
IV
Drug use food/water
Route of spread:Faeco-oral (contact, food, blood) Homo. Travel
-
· -
men
high prevelance in Asia, Africa. S. America.
·
in these countries, children are infected
early and are
asymptomatic.
if immunised,
not
mainly travelers, IV
drug users, and homo. men become infected (RFs).
chronic infection resolves and person is immunised.
·
no
-
Incubation period 2-6 weeks.
·
Investigations:HAV-Igm tive
currently infected, HAV-19Gtive resolved/immunised,
·
- -
present in stool once incubated/symptomatic, raised transaminases.
B Route of spread:blood. Most resolve, but -18% become chronic carriers.
· ·
Incubation period 1-6 months.
·
Investigations: AbsAg tive
during incubation active infection.
· -
-
-
HbsAg tive 6 months carrier status.-
Anti-HBC
Antibody tive pastinfection.
-
-
-
Anti-HBs
Antibody tive -
vaccinated.
Route of spread:blood.
C
·
most become chronic carriers,
·
and develop Liver Cirrhosis/Cancer.
HB SEROLOGY
Investigations:Anti-HDV Antibody tive pastinfection.
·
-
Spread:blood.
D. Route of
·
Only HBV Chronic carriers can
develop HDV.
Investigations:Anti-HDV Antibody tive,
·
and by extention HBsAg Hive.
E
-
·
Route of spread:Facco-oral (mostly contaminated water, uncooked pork). HEV SEROLOGY
high prevelance Asia, Africa.
in
·
4 Genotypes:Developing countries HEV1/2. Developed countries HEV 3/4.
·
=
=
Incubation period 2-6 weeks.
·
Investigations:HEV-Igm tive
currently infected, HEV-19Gttive resolved/ immunised,
·
- -
present in stool once incubated/symptomatic, raised transaminases.
·
no chronic infection -
resolves and person is immunised, except immunosuppressed individuals.
Only immunisation vaccine.
without
·
one