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,3. The nurseis teachinga patient whowill bedischarged homewithaprescription foranenteric
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-coated tablet. Which statement by the patient
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indicates understanding of the teaching? i@ i@ i@ i@



a. Imaycrush thetablet and put it inapplesaucetoimproveabsorption.
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b. I should consumeacidic foodsto enhanceabsorption ofthis medication.
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c. Ishould expect adelay in onset ofthedrugs effects aftertaking thetablet.
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d. I should takethismedication withhigh-
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fat foodsto improveits action. ANS: C
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E nteric-
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coated tablets resist disintegration in the acidic environment of the stomach and disintegrate whe
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n t heyreach the small intestine. There is usuallysome delay in onset of actionsafter taking these
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med icat ions. Enteric-
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coated tablets should not becrushed orchewed, which would alterthetimeand locationofabsorpti on
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. Acidic foods will not enhance theabsorption of the medication. The patient should not to eat hi
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gh-fat food before ingesting an enteric-coated tablet, because high-
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fat foodsdecreasethe absorption rate.
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DIF:COGNITIVELEVEL: Applying (Application) REF: dm 3 TOP pf i@ pf i@ i@ i@ i@



: NURSING PROCESS: Nursing Intervention
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MSC:NCLEX:Physiological Integrity:Pharmacological and Parenteral Therapies i@ i@ vi @ vj




4. A patient whois newlydiagnosed with type1 diabetes mellitus asks whyinsulin mustbe give n
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by subcutaneous injection instead of bymouth. Thenursewillexplain that this isbecause
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a. absorptionis diminished bythefirst-pass effects i n theliver.
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b. absorption is fasterwhen insulinisgiven subcutaneously.
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c. digestiveenzymesinthegastrointestinaltract prevent absorption. i@ i@



d. theoralformislesspredictablewithmoreadverse effects. pf pf i@ i@



A NS: C
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Insulin, growth hormones, and otherprotein-
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based drugs aredestroyed in the smallintestine by digestive enzymes and must be given parenterall
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y. Becauseinsulinisdestroyed by digestiveenzymes,it wouldnotmakeittotheliverformetabolis m
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w ithafirst-
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pass effect.Subcutaneous tissuehas fewerblood vessels, soabsorption isslowerin such tissue. Ins ul
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i n is given subcutaneously because it is desirable to have it absorb slowly.
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DIF:COGNITIVELEVEL:Understanding(Comprehension)REF:dm3 TOP: NU i@ i@ i@



RSING PROCESS: Nursing Intervention: Patient Teaching
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, MSC:NCLEX:Physiological Integrity:Pharmacological and Parenteral Therapies
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