AANP FNP PREP |ACTUAL QUESTIONS AND
VERIFIED ANSWERS|BRAND NEW 2026-2027
UPDATE|GRADED A+
Question 1
A patient tells the nurse practitioner that she recently started taking the supplement St.
John's wort after reading about its benefits online. Which of the following medications, if
being actively consumed, must be immediately stopped?
A. Benadryl
B. Famotidine (Pepcid)
C. Metformnin (Glucophage)
D. Sumatriptan (Imitrex)
CORRECT ANSWER
D. Sumatriptan (imitrex)
Sumatriptan (Imitrex) (D) is a medication used to treat migraines and belongs to a drug
class known as serotonin agonists. When used in conjunction with St. John's wort, it may
increase the risk of serotonin syndrome, a potentially life-threatening condition.
Question 2
Which of the following is not a symptom of both major depressive disorder and post-
traumatic stress disorder?
A. Difficulty concentrating
B. Hypervigilance
C. Insomnia
D. Irritabilty
1
,CORRECT ANSWER
B. Hypervigilance
In addition to difficulty concentrating, insomnia, and irritability, major depressive
disorder (MDD) may also include symptoms of depressed mood, anhedonia, weight loss
or gain, and low energy. However, hypervigilance (B) is not a symptom associated with
this diagnosis.
Question 3
A patient with type 1 diabetes presents for a follow-up visit. He has been stable on his
medication regimen but is worried because he is between jobs and will be without health
insurance coverage for a few months. He asks if there are less expensive insulin options to
get him through this time. Which of the following would be good options for this patient,
given his circumstance?
Incorrect
A.
Insulin aspart 70/30
B.
Insulin detemir
C.
Insulin isophane
D.
Insulin degludec
CORRECT ANSWER
Insulin Isophane
2
, The least expensive insulin type listed in this question is insulin isophane (C) (neutral
protamine Hagedorn insulin). There are also often pharmacy-specific coupons that can be
used on insulin, so helping patients apply for and navigate these programs can be
instrumental in managing their diabetes. Another inexpensive option is regular
insulin.Insulin analogs (glargine, detemir, degludec, lispro, and aspart) are significantly
more expensive than human insulin (isophane, regular). Insulins modified by
manufacturers, especially when sold as brand-name medications, tend to be more
expensive due to this modification. While analogs offer alternate lengths of action and
convenience, there is no well-documented clinical evidence that patient outcomes are
improved with differing brands. Therefore, maintaining a patient's blood glucose level
through outcome-focused treatment is more valuable than a process-focused plan based
on medication.
Question 4
A 40-year-old woman with type 2 diabetes presents to the clinic with concerns of spiking
blood sugar between lunch and dinner. She states she is on a rapid-acting insulin sliding
scale and long-acting insulin. Which change should be implemented to help prevent or
curb this glycemic spike?
A.
Add a dose of mealtime insulin aspart (Novolog) at lunch
B.
Add insulin detemir (Levemir) at night
C.
Increase her insulin glargine (Lantus)
D.
Prescribe a dose of neutral protamine Hagedorn insulin with dinner
CORRECT ANSWER
3
, A. Add a dose of mealtime insulin aspart (Novolog) at lunch
Insulin aspart (Novolog) (A) is a rapid acting insulin that is commonly dosed with meals
and as a sliding scale regimen based on a patient's glucose prior to eating (preprandial).
It is the appropriate insulin to add as a mealtime dose when patients experience blood
glucose spikes between meals because of its short-acting properties. Peak time action of
insulin aspart is 2 hours with initial effect within the first 30 minutes, making it an ideal
choice to control expected postprandial glycemic spikes
Question 5
Which of the following conditions is associated with an increased risk for conductive
hearing loss?
A.
Acoustic neuroma
B.
Ménière disease
C.
Otitis media
D.
Presbycusis
CORRECT ANSWER
C. Otitis media
Causes of conductive hearing loss are otitis media (C), otitis externa, foreign objects in
the ear canal, impacted ear wax, tumors, congenital anomalies, discontinuity of middle
4
VERIFIED ANSWERS|BRAND NEW 2026-2027
UPDATE|GRADED A+
Question 1
A patient tells the nurse practitioner that she recently started taking the supplement St.
John's wort after reading about its benefits online. Which of the following medications, if
being actively consumed, must be immediately stopped?
A. Benadryl
B. Famotidine (Pepcid)
C. Metformnin (Glucophage)
D. Sumatriptan (Imitrex)
CORRECT ANSWER
D. Sumatriptan (imitrex)
Sumatriptan (Imitrex) (D) is a medication used to treat migraines and belongs to a drug
class known as serotonin agonists. When used in conjunction with St. John's wort, it may
increase the risk of serotonin syndrome, a potentially life-threatening condition.
Question 2
Which of the following is not a symptom of both major depressive disorder and post-
traumatic stress disorder?
A. Difficulty concentrating
B. Hypervigilance
C. Insomnia
D. Irritabilty
1
,CORRECT ANSWER
B. Hypervigilance
In addition to difficulty concentrating, insomnia, and irritability, major depressive
disorder (MDD) may also include symptoms of depressed mood, anhedonia, weight loss
or gain, and low energy. However, hypervigilance (B) is not a symptom associated with
this diagnosis.
Question 3
A patient with type 1 diabetes presents for a follow-up visit. He has been stable on his
medication regimen but is worried because he is between jobs and will be without health
insurance coverage for a few months. He asks if there are less expensive insulin options to
get him through this time. Which of the following would be good options for this patient,
given his circumstance?
Incorrect
A.
Insulin aspart 70/30
B.
Insulin detemir
C.
Insulin isophane
D.
Insulin degludec
CORRECT ANSWER
Insulin Isophane
2
, The least expensive insulin type listed in this question is insulin isophane (C) (neutral
protamine Hagedorn insulin). There are also often pharmacy-specific coupons that can be
used on insulin, so helping patients apply for and navigate these programs can be
instrumental in managing their diabetes. Another inexpensive option is regular
insulin.Insulin analogs (glargine, detemir, degludec, lispro, and aspart) are significantly
more expensive than human insulin (isophane, regular). Insulins modified by
manufacturers, especially when sold as brand-name medications, tend to be more
expensive due to this modification. While analogs offer alternate lengths of action and
convenience, there is no well-documented clinical evidence that patient outcomes are
improved with differing brands. Therefore, maintaining a patient's blood glucose level
through outcome-focused treatment is more valuable than a process-focused plan based
on medication.
Question 4
A 40-year-old woman with type 2 diabetes presents to the clinic with concerns of spiking
blood sugar between lunch and dinner. She states she is on a rapid-acting insulin sliding
scale and long-acting insulin. Which change should be implemented to help prevent or
curb this glycemic spike?
A.
Add a dose of mealtime insulin aspart (Novolog) at lunch
B.
Add insulin detemir (Levemir) at night
C.
Increase her insulin glargine (Lantus)
D.
Prescribe a dose of neutral protamine Hagedorn insulin with dinner
CORRECT ANSWER
3
, A. Add a dose of mealtime insulin aspart (Novolog) at lunch
Insulin aspart (Novolog) (A) is a rapid acting insulin that is commonly dosed with meals
and as a sliding scale regimen based on a patient's glucose prior to eating (preprandial).
It is the appropriate insulin to add as a mealtime dose when patients experience blood
glucose spikes between meals because of its short-acting properties. Peak time action of
insulin aspart is 2 hours with initial effect within the first 30 minutes, making it an ideal
choice to control expected postprandial glycemic spikes
Question 5
Which of the following conditions is associated with an increased risk for conductive
hearing loss?
A.
Acoustic neuroma
B.
Ménière disease
C.
Otitis media
D.
Presbycusis
CORRECT ANSWER
C. Otitis media
Causes of conductive hearing loss are otitis media (C), otitis externa, foreign objects in
the ear canal, impacted ear wax, tumors, congenital anomalies, discontinuity of middle
4
