Pearson Reviews & Rationales: Pharmacology | Clinical Judgment Edition
CLINICAL JUDGMENT PHARMACOLOGY
Pearson Reviews & Rationales: Pharmacology
4th Edition
1,200 Chapter-Aligned NCLEX-Style Questions
Answers + Detailed Rationales + SATA + Medication Safety + Clinical Judgment
Page 1
, Pearson Reviews & Rationales: Pharmacology | Clinical Judgment Edition
How This Exam Bank Is Built
Chapter-by-chapter design.
Question variety. The bank deliberately rotates clinical situations, monitoring questions, patient teaching,
adverse-effect recognition, contraindications, interactions, expected outcomes, administration decisions,
calculations, and select-all-that-apply items so stems do not repeatedly begin the same way.
Clinical-use caution. This is an exam-preparation resource, not a prescribing reference. Drug labeling and
protocols change; clinical users should verify current labeling, institutional policy, and patient-specific
orders.
Chapter / Section Question Map
# Chapter / Section Questions
1 Basic Principles and Safety in 1-75
Pharmacology
2 Herbal Agents 76-150
3 Neurological and 151-225
Musculoskeletal System
Medications
4 Psychiatric Medications 226-300
5 Respiratory System Medications 301-375
6 Cardiac Medications 376-450
7 Blood Modifying Agents 451-525
8 Renal System Medications 526-600
9 Gastrointestinal System 601-675
Medications
10 Immune System Medications 676-750
11 Anti-Infective Medications 751-825
12 Antineoplastic Medications 826-900
13 Endocrine System Medications 901-975
14 Reproductive System 976-1050
Medications
15 Integumentary System 1051-1125
Medications
Page 2
, Pearson Reviews & Rationales: Pharmacology | Clinical Judgment Edition
16 Visual and Auditory Medications 1126-1200
Page 3
, Pearson Reviews & Rationales: Pharmacology | Clinical Judgment Edition
1. Basic Principles and Safety in Pharmacology
1. The nurse compares today’s assessment with baseline findings for a patient on metoclopramide.
Which change is the strongest safety signal?
A. improved gastric emptying or reduced nausea without movement disorder
B. tardive dyskinesia or neuroleptic malignant syndrome
C. minor local discomfort at an injection site
D. temporary mild fatigue
Correct Answer: B | Rationale: A major safety concern with metoclopramide is tardive dyskinesia or
neuroleptic malignant syndrome. This finding warrants prompt assessment because it can represent a
serious medication-related complication. A is not selected because "improved gastric emptying or reduced
nausea without movement disorder" does not match the key serious consideration in this scenario. B is
correct because it matches the medication-specific serious principle being tested. C is not selected because
"minor local discomfort at an injection site" does not match the key serious consideration in this scenario.
D is not selected because "temporary mild fatigue" does not match the key serious consideration in this
scenario.
2. Which home-care instruction best reduces a known risk of lactulose?
A. avoid alcohol and do not stop long-term therapy abruptly
B. report tinnitus, hearing loss, dizziness, or reduced urine output
C. stop and contact the prescriber promptly for fever or sore throat
D. for encephalopathy, dosing is titrated to prescribed stool goal
Correct Answer: D | Rationale: A key self-management instruction for lactulose is to for
encephalopathy, dosing is titrated to prescribed stool goal. The teaching links the drug’s principal risks with
a practical action the patient can take. A is not selected because "avoid alcohol and do not stop long-term
therapy abruptly" does not match the key teach consideration in this scenario. B is not selected because
"report tinnitus, hearing loss, dizziness, or reduced urine output" does not match the key teach
consideration in this scenario. C is not selected because "stop and contact the prescriber promptly for fever
or sore throat" does not match the key teach consideration in this scenario. D is correct because it matches
the medication-specific teach principle being tested.
3. The nurse evaluates the response to loperamide. Which finding is the clearest evidence of benefit?
A. tumor response without severe cystitis or myelosuppression
B. relief of acid-related symptoms and ulcer healing
C. normal thyroid function and improved hypothyroid symptoms
D. reduced stool frequency without ileus
Page 4
CLINICAL JUDGMENT PHARMACOLOGY
Pearson Reviews & Rationales: Pharmacology
4th Edition
1,200 Chapter-Aligned NCLEX-Style Questions
Answers + Detailed Rationales + SATA + Medication Safety + Clinical Judgment
Page 1
, Pearson Reviews & Rationales: Pharmacology | Clinical Judgment Edition
How This Exam Bank Is Built
Chapter-by-chapter design.
Question variety. The bank deliberately rotates clinical situations, monitoring questions, patient teaching,
adverse-effect recognition, contraindications, interactions, expected outcomes, administration decisions,
calculations, and select-all-that-apply items so stems do not repeatedly begin the same way.
Clinical-use caution. This is an exam-preparation resource, not a prescribing reference. Drug labeling and
protocols change; clinical users should verify current labeling, institutional policy, and patient-specific
orders.
Chapter / Section Question Map
# Chapter / Section Questions
1 Basic Principles and Safety in 1-75
Pharmacology
2 Herbal Agents 76-150
3 Neurological and 151-225
Musculoskeletal System
Medications
4 Psychiatric Medications 226-300
5 Respiratory System Medications 301-375
6 Cardiac Medications 376-450
7 Blood Modifying Agents 451-525
8 Renal System Medications 526-600
9 Gastrointestinal System 601-675
Medications
10 Immune System Medications 676-750
11 Anti-Infective Medications 751-825
12 Antineoplastic Medications 826-900
13 Endocrine System Medications 901-975
14 Reproductive System 976-1050
Medications
15 Integumentary System 1051-1125
Medications
Page 2
, Pearson Reviews & Rationales: Pharmacology | Clinical Judgment Edition
16 Visual and Auditory Medications 1126-1200
Page 3
, Pearson Reviews & Rationales: Pharmacology | Clinical Judgment Edition
1. Basic Principles and Safety in Pharmacology
1. The nurse compares today’s assessment with baseline findings for a patient on metoclopramide.
Which change is the strongest safety signal?
A. improved gastric emptying or reduced nausea without movement disorder
B. tardive dyskinesia or neuroleptic malignant syndrome
C. minor local discomfort at an injection site
D. temporary mild fatigue
Correct Answer: B | Rationale: A major safety concern with metoclopramide is tardive dyskinesia or
neuroleptic malignant syndrome. This finding warrants prompt assessment because it can represent a
serious medication-related complication. A is not selected because "improved gastric emptying or reduced
nausea without movement disorder" does not match the key serious consideration in this scenario. B is
correct because it matches the medication-specific serious principle being tested. C is not selected because
"minor local discomfort at an injection site" does not match the key serious consideration in this scenario.
D is not selected because "temporary mild fatigue" does not match the key serious consideration in this
scenario.
2. Which home-care instruction best reduces a known risk of lactulose?
A. avoid alcohol and do not stop long-term therapy abruptly
B. report tinnitus, hearing loss, dizziness, or reduced urine output
C. stop and contact the prescriber promptly for fever or sore throat
D. for encephalopathy, dosing is titrated to prescribed stool goal
Correct Answer: D | Rationale: A key self-management instruction for lactulose is to for
encephalopathy, dosing is titrated to prescribed stool goal. The teaching links the drug’s principal risks with
a practical action the patient can take. A is not selected because "avoid alcohol and do not stop long-term
therapy abruptly" does not match the key teach consideration in this scenario. B is not selected because
"report tinnitus, hearing loss, dizziness, or reduced urine output" does not match the key teach
consideration in this scenario. C is not selected because "stop and contact the prescriber promptly for fever
or sore throat" does not match the key teach consideration in this scenario. D is correct because it matches
the medication-specific teach principle being tested.
3. The nurse evaluates the response to loperamide. Which finding is the clearest evidence of benefit?
A. tumor response without severe cystitis or myelosuppression
B. relief of acid-related symptoms and ulcer healing
C. normal thyroid function and improved hypothyroid symptoms
D. reduced stool frequency without ileus
Page 4
