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What is the Treatment for Gonorrhea?
a. Rocephin (Ceftriaxone) 250mg IM and Azithromycin 1 gm po x1 or doxy 100mg BID
x7 days
b. Azithromycin 1 gm po x1 only
,c. Doxycycline 100mg BID x7 days only
d. Penicillin G 2.4 million units IM
✔️ Correct Answer: A
Rationale:
Gonorrhea is treated with dual therapy: Ceftriaxone 250mg IM (for gonococcal
coverage) plus Azithromycin 1g PO or Doxycycline 100mg BID for 7 days (for concurrent
chlamydia coverage). This dual therapy is recommended due to increasing antibiotic
resistance. Options B, C, and D are incomplete or incorrect regimens.
What is the Treatment for Chlamydia?
a. Azithromycin 1 gm po x1 or doxy 100 mg BID x 7 days or Amoxicillin 500 mg po TID x
7 days
b. Ceftriaxone 250mg IM only
c. Penicillin VK 500mg QID x10 days
d. Metronidazole 500mg BID x7 days
✔️ Correct Answer: A
Rationale:
Chlamydia is treated with Azithromycin 1g PO single dose, Doxycycline 100mg BID for 7
days, or Amoxicillin 500mg TID for 7 days (for pregnant women). Test for cure should be
done 3 weeks after completion of treatment. Doxycycline is contraindicated in
pregnancy.
,What is the Treatment for Bacterial Vaginosis?
a. Flagyl BID x 7 days
b. Metronidazole 2g PO single dose
c. Clindamycin cream vaginal x7 days
d. Doxycycline 100mg BID x7 days
✔️ Correct Answer: A
Rationale:
Bacterial vaginosis is treated with Metronidazole 500mg BID for 7 days (Flagyl).
Alternative regimens include Metronidazole 2g PO single dose or Clindamycin cream 5g
vaginally for 7 days. Option A is the standard recommended regimen.
What is the vaginitis treatment?
a. Diflucan 100mg x1
b. Metronidazole 500mg BID x7 days
c. Clotrimazole cream x7 days
d. Doxycycline 100mg BID x7 days
✔️ Correct Answer: A
Rationale:
Vaginitis (specifically vulvovaginal candidiasis) is treated with Fluconazole (Diflucan)
, 150mg PO single dose. Option A (100mg x1) is close but the standard dose is 150mg.
However, the key point is that Diflucan is the treatment of choice for yeast vaginitis.
What is the diagnosis and treatment for Rocky Mountain Spotted Fever?
a. PCR assay with Rickettsia antigen; tx: doxycycline
b. Serology for Borrelia burgdorferi; tx: amoxicillin
c. Skin biopsy; tx: cephalexin
d. Blood culture; tx: azithromycin
✔️ Correct Answer: A
Rationale:
Rocky Mountain Spotted Fever (RMSF) is diagnosed by PCR assay detecting Rickettsia
rickettsii antigen. Treatment is Doxycycline, which should be initiated empirically based
on clinical suspicion without waiting for confirmatory testing, as RMSF can be fatal if
treatment is delayed. Option A is correct.
What is the diagnosis and treatment for Lyme disease (erythema migrans)?
a. Dx: B. burgdorferi via ELISA then confirm with Western blot; TX: doxycycline or
amoxicillin if less than 7 years
b. Dx: PCR for Rickettsia; TX: doxycycline