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NCLEX Medical-Surgical Nursing 500 Practice Questions — 30-Question Sample 2026/2027

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Review medical-surgical nursing concepts with 30 original NCLEX-style questions from a larger 500-question practice collection. Designed for candidates seeking additional adult health nursing practice and clinical reasoning preparation.

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PAPER N26: NCLEX MEDICAL-
SURGICAL 500 (SAMPLE 30)



Title: NCLEX Medical-Surgical 500: Sample
30 of 500 with Rationales




Keywords: Medical-surgical nursing, med-surg,
NCLEX med-surg, nursing practice questions,
nursing test bank, NCLEX prep

,Questions

1. A nurse is caring for a client with pneumonia. Which

finding indicates improvement? A) Increased sputum

production B) Decreased oxygen saturation C) Decreased

fever and improved breath sounds D) Increased respiratory

rate


Explanation: Improvement is indicated by decreased fever,

reduced sputum production, and improved breath sounds.


2. A client with COPD is receiving oxygen. Which method is

most appropriate? A) Non-rebreather mask B) Venturi

mask C) Partial rebreather mask D) Simple face mask


Explanation: The Venturi mask delivers a precise concentration

of oxygen, making it the safest option for COPD clients.

, 3. A nurse is caring for a client with a new colostomy. Which

finding indicates a complication? A) Stoma is pink and

moist B) Stoma is dark red and dry C) Small amount of

bleeding from the stoma D) Stoma is slightly swollen


Explanation: A dark red, dry stoma indicates ischemia and poor

circulation. A healthy stoma should be pink, moist, and slightly

swollen.


4. A client with heart failure is prescribed furosemide. Which

finding indicates effectiveness? A) Weight gain of 2

pounds B) Decreased shortness of breath C) Increased

edema D) Crackles in the lung bases


Explanation: Decreased shortness of breath indicates reduced

fluid overload and improvement in heart failure symptoms.

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